29 completed, 14 unknown, 4 terminated, 3 not yet recruiting. 40 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 40 | Completed 22, Unknown 11, Terminated 3, Recruiting 2, Not yet recruiting 1, Withdrawn 1 |
Follow Noninvasive Ventilation: new trials by email Literature Review of Noninvasive Ventilation trials Research Report on Noninvasive Ventilation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HERMES: Quality and Safety of Advanced Respiratory Support During Patient Transport Advanced Respiratory Support During Patient Transport - Acute Respiratory Failure, Respiratory Insufficiency | Not yet recruiting | Medipol University | 565 | 2026-12-31 | 2026-09-04 | |
| RESET-COPD Cohort: Real-Time Monitoring and Early Warning in COPD Patients Receiving Home NPPV Not applicable- observational study - Pulmonary Disease, Chronic Obstructive (COPD), Chronic Respiratory Failure With Hypercapnia | Recruiting | Beijing Chao Yang Hospital | 250 | 2026-09-29 | 2026-10-19 | |
| High PEEP in Noninvasive Ventilation Patients With Pneumonia or ARDS The level of PEEP during noninvasive ventilation - Noninvasive Ventilation, Pneumonia | Not applicable | Recruiting | Chongqing Medical University | 706 | 2026-01-04 | 2026-01-07 |
| Synchrony-Optimized Non-Invasive Ventilation Education Program and ICU Patients SYNC-NIV - Ventilator Associated Events, Asynchrony, Patient-Ventilator | Not applicable | Not yet recruiting | Shahid Beheshti University of Medical Sciences | 92 | 2025-12-19 | 2025-12-24 |
| Comparison of the Silverman-Andersen Score and the Downes Score Respiratory Distress Neonatal, Noninvasive Ventilation | Not yet recruiting | Muğla Sıtkı Koçman University | 220 | 2025-09-15 | 2025-09-19 | |
| Epidemiology of Non- Invasive Mechanical Ventilation in Argentina: a Multicenter Observational Study Respiration, Artificial, Noninvasive Ventilation | Enrolling by invitation | Argentinian Intensive Care Society | 246 | 2025-05-01 | 2025-05-31 | |
| Effects of Face Mask Continuous Positive Airway Pressure Vs. Noninvasive Ventilation Vs. High-flow Nasal Oxygen on Intubation-free Survival in Acute Hypoxemic Respiratory Failure: the TRIPOD Randomized Clinical Trial Continuous Positive Airway Pressure, High-flow nasal oxygen, Non-invasive ventilation - Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy | Not applicable | Recruiting | Southeast University, China | 1300 | 2025-01-23 | 2025-02-26 |
| The Effect of Mask Design on Transcutaneous Carbon Dioxide in Healthy Volunteers: A Pilot Clinical Investigation Non-invasive ventilation (NIV) - Healthy Volunteers, Noninvasive Ventilation | Not applicable | Completed | Fisher and Paykel Healthcare | 10 | 2024-11-18 | 2025-04-24 |
| A Safety Assessment of the iZephyr Hood for NIV in COVID-19 Patients iZephyr hood - Aerosol Disease, Covid19 | Not applicable | Unknown | Imperial College Healthcare NHS Trust | 30 | 2024-06-01 | 2024-03-13 |
| Nutrition Under Noninvasive Ventilation Noninvasive Ventilation, Nutrition Therapy | Completed | Università degli Studi del Piemonte Orientale Amedeo Avogadro | 112 | 2024-03-01 | 2024-12-13 | |
| Point-of-Care Lung Ultrasound for Prognosis in Critically Ill Infants With Acute Lower Respiratory Tract Infection Bronchiolitis, Noninvasive Ventilation | Unknown | Vittore Buzzi Children's Hospital | 100 | 2024-01-01 | 2024-05-22 | |
| Custom Non-invasive Ventilation Masks in Children Custom mask, Current commercial mask - Noninvasive Ventilation, Child, Only | Not applicable | Completed | University of Alberta | 16 | 2023-12-15 | 2026-09-09 |
| Prehospital Non-invasive Ventilation for Acute Exacerbation of Chronic Obstructive Pulmonary Disease Non-invasive ventilation - COPD Exacerbation, COPD Exacerbation Acute | Not applicable | Unknown | Central Denmark Region | 140 | 2023-12-08 | 2024-01-18 |
| Impact of Noninvasive With Expiratory Washout on Respiratory Rate of Patients With Acute Hypercapnic Respiratory Failure Vela Investigational Mask, Nivairo Standard Mask - Noninvasive Ventilation | Not applicable | Unknown | Fisher and Paykel Healthcare | 20 | 2023-11-01 | 2023-07-27 |
| Effect of Web-Based Adaptation and Insomnia Severity in Individuals Using Noninvasive Ventilators at Home Web-based education - Noninvasive Ventilation, COPD | Not applicable | Completed | KTO Karatay University | 80 | 2023-10-15 | 2026-09-02 |
| HERMES: International Survey and Portable External Power Evaluation During Respiratory Support Transport Portable External Power Supply - Patient Transport, Respiratory Failure | Completed | Medipol University | 246 | 2023-02-20 | 2026-09-09 | |
| NHFOV Vs NIPPV Post-extubation in Preterm Neonates noninvasive high frequency oscillation ventilation, noninvasive positive pressure ventilation - Noninvasive Ventilation | Not applicable | Completed | Kafrelsheikh University | 80 | 2023-01-20 | 2024-10-24 |
| Efficacy and Safety of High-Flow Nasal Cannula Versus Noninvasive Ventilation for Pulmonary Arterial Hypertension-Associated Acute Respiratory Failure HFNC treatment, NIV treatment - Pulmonary Arterial Hypertension, Acute Respiratory Failure | Unknown | The First People's Hospital of Neijiang | 90 | 2023-01-01 | 2024-09-03 | |
| Prospective Development and Validation of an Objective Classification for Difficult Facemask Ventilation: the MASCAN Score Airway Management, Mask Ventilation | Active not recruiting | Universitätsklinikum Hamburg-Eppendorf | 423 | 2022-11-07 | 2025-12-10 | |
| Low Versus High PEEP in Noninvasive Ventilation for Hypoxemic Respiratory Failure Different level of PEEP - Noninvasive Ventilation | Not applicable | Completed | Chongqing Medical University | 380 | 2022-01-11 | 2025-01-24 |
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Respiratory Insufficiency (12) · Pulmonary Disease, Chronic Obstructive (8) · Respiratory Aspiration (4) · Dyspnea (3) · COVID-19 (2) · Hypoxia (2) · Neuromuscular Diseases (2) · Obesity (2) · Acute Lung Injury (1) · Airway Remodeling (1) · Amyotrophic Lateral Sclerosis (1) · Anxiety Disorders (1) · Bronchiolitis (1) · Critical Illness (1) · Depression (1)
Respiratory Tract Diseases (32) · Respiration Disorders (21) · Pathological Conditions, Signs and Symptoms (20) · Lung Diseases (16) · Pathologic Processes (13) · Disease Attributes (9) · Lung Diseases, Obstructive (9) · Signs and Symptoms (9) · Chronic Disease (8) · Signs and Symptoms, Respiratory (7) · Infections (4) · Nutritional and Metabolic Diseases (4) · Respiratory Tract Infections (4) · Behavior (3) · Body Weight (3)
Noninvasive Ventilation (8) · Clinical Protocols (2) · Cannula (1) · Continuous Positive Airway Pressure (1) · Interactive Ventilatory Support (1) · Masks (1) · Methods (1) · Remote Consultation (1) · Standard of Care (1)
Chongqing Medical University (3) · Fisher and Paykel Healthcare (2) · Medipol University (2) · University Medical Center Groningen (2) · University of Alberta (2) · Anita Vukovic (1) · Argentinian Intensive Care Society (1) · Attikon Hospital (1) · Baskent University (1) · Beijing Chao Yang Hospital (1) · Beijing YouAn Hospital (1) · Central Denmark Region (1) · Centre d'Investigation Clinique et Technologique 805 (1) · Chinese University of Hong Kong (1) · Convergent Engineering, Inc. (1)
China (8) · United States (7) · Turkey (Türkiye) (6) · Italy (5) · Spain (5) · Canada (3) · Egypt (3) · France (3) · Germany (3) · Netherlands (3) · Qatar (3) · Hong Kong (2) · Argentina (1) · Chile (1) · Colombia (1)
Anna Grigoriadou, MSc (1) · Antonio Esquinas (1) · Antonio M Esquinas (1) · Anucha Thatrimontrichai, M.D. (1) · Begum Ergan (1) · Boris Mraovic, MD (1) · Carlo Agostoni, MD (1) · Cristina Embid, MD (1) · Cristina Ramos-Navarro (1) · Doina Precup, PhD (1)
PMID 11179136, PMID 12212984, PMID 14738245, PMID 16155782, PMID 17126543, PMID 1756837, PMID 17652681, PMID 18512045, PMID 19213769, PMID 19935062, PMID 20059598, PMID 20388753, PMID 20408932, PMID 20819144, PMID 21861914, PMID 22171400, PMID 22420583, PMID 23255684, PMID 23359457, PMID 2376246, PMID 24157199, PMID 24238745, PMID 24482704, PMID 24598245, PMID 24759325, PMID 24912564, PMID 25066329, PMID 25318667, PMID 25524958, PMID 25559697, PMID 26235150, PMID 26418151, PMID 26746384, PMID 27560387, PMID 27698560, PMID 28528348, PMID 28721033, PMID 28839495, PMID 28851800, PMID 29430443, PMID 29531743, PMID 29879495, PMID 29945735, PMID 29962738, PMID 30545968, PMID 30924897, PMID 31236018, PMID 32086337, PMID 32156788, PMID 32281941
2025 (1), R43HL147788 (1)