10 unknown, 9 completed, 3 recruiting, 2 not yet recruiting. 17 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 17 | Unknown 8, Completed 5, Not yet recruiting 2, Active not recruiting 1, Terminated 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Non-invasive Ventilation: new trials by email Literature Review of Non-invasive Ventilation trials Research Report on Non-invasive Ventilation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| VENTILATION DURING SPACEFLIGHT (PHASE 2) non-invasive oxygenation strategies - Non-invasive Ventilation | Not applicable | Not yet recruiting | Centre Hospitalier Régional Metz-Thionville | 12 | 2026-10-06 | 2026-09-25 |
| A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS) Non-invasive ventilation - Amyotrophic Lateral Sclerosis (ALS), Chronic Respiratory Failure | Phase 2 | Recruiting | University of Pennsylvania | 48 | 2026-06-11 | 2026-06-26 |
| An International Survey on the Use of NIV Outside the ICU Non-invasive Ventilation, Intensive Care (ICU) | Completed | Dr. Ram Manohar Lohia Hospital | 600 | 2025-09-02 | 2026-10-22 | |
| Non-invasive Ventilation and Dexmedetomidine in Critically Ill Adults Dexmedetomidine, Placebo Control - Non-Invasive Ventilation | Phase 3 | Recruiting | St. Joseph's Healthcare Hamilton | 846 | 2025-07-29 | 2025-09-10 |
| Effects of Vibrating Mesh Nebulisation in Patients With COPD During Non-invasive Ventilation (VMN-NIV) Vibrating mesh nebulisation, Jet nebuliser - COPD (Chronic Obstructive Pulmonary Disease), Non-invasive Ventilation | Not applicable | Active not recruiting | Guy's and St Thomas' NHS Foundation Trust | 12 | 2025-04-08 | 2026-07-10 |
| The Inflate Study; Defining the Soft Palate in the Upper Airway Flow Pathway non-invasive ventilation - Focus of the Study is the Anatomy of the Soft Palate, Non-invasive Ventilation | Not applicable | Not yet recruiting | Fisher and Paykel Healthcare | 50 | 2025-03-25 | 2025-03-05 |
| Improving Chronic Nocturnal Noninvasive Ventilation: a Multimodality Approach Non-invasive ventilation - Chronic Respiratory Failure, Non-invasive Ventilation | Recruiting | University Medical Center Groningen | 100 | 2024-12-01 | 2026-07-02 | |
| Optimization of Positive End Expiratory Pressure by Use of Pulmonary Ultrasound for Patients With Blunt Chest Trauma Treated by Non-Invasive Ventilation (Opti-PEP). Lung Ultrasound for PEEP setting, Non invasive ventilation session, Arterial blood gas - Thoracic Injuries, Non-invasive Ventilation | Not applicable | Terminated | University Hospital, Montpellier | 19 | 2023-12-19 | 2026-06-01 |
| Assessment Of Different Indices in Prediction of Noninvasive Ventilation Failure in Patients With Acute Respiratory Failure non invasive ventilation - Non-invasive Ventilation | Unknown | Assiut University | 70 | 2023-06-01 | 2023-05-09 | |
| Clinical Impact of Patient-ventilator Asynchrony Transcutaneous Capnography - Chronic Respiratory Failure, Non-invasive Ventilation | Completed | Nantes University Hospital | 35 | 2023-06-01 | 2025-03-04 | |
| The Difference Between Non-invasive High-frequency Oscillatory Ventilation and Non-invasive Continuous Airway Pressure Ventilation in COVID-19 With Acute Hypoxemia Non-invasive high-frequency oscillatory ventilation, Non-invasive continuous positive airway pressure ventilation - COVID-19 Pneumonia, Non-invasive Ventilation | Not applicable | Unknown | Guangzhou Institute of Respiratory Disease | 20 | 2023-02-10 | 2023-01-31 |
| Effect of Noninvasive High Frequency Oscillatory Ventilation on Improving CO2 Clearance in COPD Patients Non-invasive high-frequency oscillatory, Noninvasive Bilevel Positive Pressure Ventilation - COPD Exacerbation, Non-invasive Ventilation | Not applicable | Unknown | Guangzhou Institute of Respiratory Disease | 12 | 2023-02-10 | 2023-02-10 |
| Exploration of Non-invasive High-frequency Oscillations in Human-machine Asynchrony in Healthy Subjects Non-invasive high-frequency oscillatory ventilation, Noninvasive Bilevel Positive Pressure Ventilation - Non-invasive Ventilation, Healthy Subjects | Not applicable | Unknown | Guangzhou Institute of Respiratory Disease | 10 | 2022-07-15 | 2022-07-07 |
| Effect of Noninvasive High Frequency Oscillatory Ventilation on Improving Carbon Dioxide Clearance in AECOPD Patients Non-invasive high-frequency oscillatory ventilation, Noninvasive Bilevel Positive Pressure Ventilation - COPD, Non-invasive Ventilation | Not applicable | Unknown | Guangzhou Institute of Respiratory Disease | 10 | 2022-06-30 | 2022-06-28 |
| The Influence of Non-invasive Ventilation on Metabolism in Healthy Volunteers non-invasive ventilation - Energy Expenditure, Non-invasive Ventilation | Not applicable | Completed | Universitair Ziekenhuis Brussel | 5 | 2020-01-01 | 2020-08-03 |
| Patient-ventilator Asychrony During Non-invasive Ventilation When COPD Patients Doing Exercise COP, Non-invasive Ventilation | Unknown | Guangzhou Medical University | 10 | 2019-11-01 | 2021-02-23 | |
| Open Lung Strategy During Non-Invasive Respiratory Support of Very Preterm Infants in the Delivery Room openCPAP, standardCPAP - Respiratory Distress Syndrome in Premature Infant, Non-invasive Ventilation | Not applicable | Completed | Dokuz Eylul University | 145 | 2019-07-01 | 2023-05-10 |
| Tissue Doppler Ultrasound During Spontaneous Breathing and Non-invasive Ventilation in the Post-extubation Period. Post-extubation TDI - Acute Respiratory Failure, Non-invasive Ventilation | Not applicable | Unknown | Azienda Ospedaliero Universitaria Maggiore della Carita | 20 | 2019-04-01 | 2019-07-23 |
| Asynchronies in NIV With External Gas external gas during NIV - Non-invasive Ventilation | Completed | Corporacion Parc Tauli | 7 | 2018-04-01 | 2021-05-13 | |
| Comparison of Patient Work of Breathing and Tidal Volumes With High Flow Nasal Cannula Oxygen Therapy and NIV (Non-Invasive Ventilation) After Extubation in the ICU. High-Flow Nasal Oxygen / Non-invasive ventilation / Standard oxygen - ICU, Extubation | Not applicable | Unknown | Poitiers University Hospital | 25 | 2018-03-06 | 2019-07-31 |
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Pulmonary Disease, Chronic Obstructive (5) · Patient-Ventilator Asynchrony (2) · Amyotrophic Lateral Sclerosis (1) · Apnea (1) · Bronchiolitis (1) · Cognitive Dysfunction (1) · Emergencies (1) · Lung Diseases (1) · Lung Injury (1) · Neuromuscular Diseases (1) · Respiratory Distress Syndrome (1) · Respiratory Insufficiency (1) · Thoracic Injuries (1)
Respiratory Tract Diseases (12) · Pathological Conditions, Signs and Symptoms (9) · Lung Diseases (7) · Disease Attributes (6) · Lung Diseases, Obstructive (6) · Pathologic Processes (6) · Chronic Disease (5) · Respiration Disorders (5) · Signs and Symptoms (3) · Signs and Symptoms, Respiratory (3) · Respiratory Insufficiency (2) · Wounds and Injuries (2) · Bronchial Diseases (1) · Bronchitis (1) · Central Nervous System Diseases (1)
Noninvasive Ventilation (8) · Blood Gas Analysis (1) · Continuous Positive Airway Pressure (1) · Dexmedetomidine (1) · Magnetic Resonance Spectroscopy (1) · methyl hydroxyethyl cellulose (1)
Guangzhou Institute of Respiratory Disease (4) · Ali Yurtseven (1) · Assiut University (1) · Azienda Ospedaliero Universitaria Maggiore della Carita (1) · Centre Hospitalier Régional Metz-Thionville (1) · Centre Hospitalier Universitaire Vaudois (1) · Corporacion Parc Tauli (1) · Dokuz Eylul University (1) · Dr. Ram Manohar Lohia Hospital (1) · Fisher and Paykel Healthcare (1) · Guangzhou Medical University (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Icadom (1) · Nantes University Hospital (1) · Poitiers University Hospital (1)
France (5) · China (3) · Switzerland (2) · Turkey (Türkiye) (2) · Belgium (1) · Canada (1) · Germany (1) · India (1) · Italy (1) · Netherlands (1) · New Zealand (1) · Spain (1) · United Kingdom (1) · United States (1)
Alban Lovis (1) · Alys Clark (1) · Antonio M Esquinas, MD, PhD, FCCP, FNIV, FBCV (1) · Catherine I Beigelman-Aubry, MD (1) · Cristina Lalmolda, RT PhD (1) · Eui-Sik Suh, MBBS MChem(Oxon) PhD FRCP (1) · Funda Tuzun, Assoc.Prof. (1) · Hasan Ozkan, Prof. (1) · Jason T Ackrivo, MD, MSCE (1) · Jianyi Niu, M.D. (1) · Joop Jonckheer, MD (1) · Kimberley Lewis, MD (1)