49 completed, 6 terminated, 4 recruiting, 3 active not recruiting. 25 Not applicable, 12 Phase 2, 11 Phase 3, 7 Phase 4, 3 Phase 1.
Follow Neonatal Abstinence Syndrome: new trials by email Literature Review of Neonatal Abstinence Syndrome trials Research Report on Neonatal Abstinence Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Recorded Parent/Caregiver Voice for Infants With Neonatal Opioid Withdrawal Syndrome Recorded Parent/Caregiver Voice Playback - Neonatal Opioid Withdrawal Syndrome, Prenatal Opioid Exposure | Not applicable | Not yet recruiting | University of Manitoba | 20 | 2026-11-01 | 2026-10-08 |
| Effective Caregiving for Neonatal Abstinence Syndrome: Testing an Instructional Mobile Technology Platform for High-Risk Pregnant Women Mobile-based NAS Caregiving Tool - Neonatal Abstinence Syndrome, Opioid-use Disorder | Not applicable | Active not recruiting | Washington State University | 30 | 2024-07-25 | 2026-10-29 |
| An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care (SUPPORT) An implementation model for co-located Medications for Opioid Use Disorder (MOUD) prescription in the NICU - Opioid Use Disorder, Neonatal Abstinence Syndrome | Not applicable | Recruiting | University of Pennsylvania | 50 | 2024-07-01 | 2026-07-06 |
| Study to Collect Data for Neonatal Abstinence Syndrome (NAS) and Evaluate the Automated Data Collection Process NeoMonki - Neonatal Abstinence Syndrome | Enrolling by invitation | Rekovar Inc. | 100 | 2024-03-18 | 2025-09-09 | |
| The Alberta Neonatal Abstinence Syndrome Mother-Baby Care ImprovEmeNT Program Rooming-in care, Baseline standard of care - Neonatal Abstinence Syndrome | Not applicable | Recruiting | University of Alberta | 240 | 2023-10-01 | 2025-09-17 |
| Neurostimulation to Improve NOWS Outcomes Sparrow Fledging Therapy System, Sham Sparrow Fledging Therapy System - Neonatal Opioid Withdrawal Syndrome, Neonatal Abstinence Syndrome | Not applicable | Active not recruiting | Spark Biomedical, Inc. | 52 | 2022-07-27 | 2026-06-02 |
| Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study Buprenorphine Injection, Buprenorphine Sublingual Product - Opioid-Related Disorders, Drug Addiction | Completed | T. John Winhusen, PhD | 71 | 2021-06-14 | 2026-03-16 | |
| Actigraphy and Neonatal Abstinence Syndrome of Hospitalized Newborn in Intensive Care Units Actigraphy, eTact - Neonatal Abstinence Syndrome | Not applicable | Unknown | University Hospital, Caen | 50 | 2021-03-01 | 2021-07-30 |
| A Trial to Determine Weight Gain Benefits of Caloric Supplementation for NAS Infants High-calorie formula - Neonatal Abstinence Syndrome | Not applicable | Completed | Yale University | 39 | 2020-12-04 | 2026-06-30 |
| Averting NAS Among Opioid-Using Young Women Receiving MAT Using Buprenorphine Motivational Interviewing and Educational Training (MIET) - Opioid-use Disorder, Contraception | Not applicable | Unknown | Meharry Medical College | 80 | 2020-11-01 | 2020-11-02 |
| Randomized Control Trial of Buprenorphine vs. Morphine for the Treatment of Neonatal Opioid Withdrawal Syndrome (NOWS) Buprenorphine or Placebo, Morphine or Placebo - Neonatal Opioid Withdrawal Syndrome | Phase 3 | Withdrawn | Women and Infants Hospital of Rhode Island | 2020-10-01 | 2023-06-22 | |
| Clinical Trial to Decrease Length of Stay in Infants With Neonatal Abstinence Syndrome With an Exclusive Human Milk Diet Human Milk, Standard of Care - Neonatal Abstinence Syndrome | Not applicable | Completed | The University of Texas Health Science Center at San Antonio | 19 | 2020-08-31 | 2025-07-08 |
| Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study Buprenorphine Injection, Buprenorphine Sublingual Product - Opioid-Related Disorders, Drug Addiction | Completed | T. John Winhusen, PhD | 97 | 2020-07-21 | 2026-03-16 | |
| Medication Treatment for Opioid Use Disorder in Expectant Mothers Buprenorphine Injection, Buprenorphine Sublingual Product - Opioid-Related Disorders, Drug Addiction | Phase 3 | Completed | T. John Winhusen, PhD | 140 | 2020-07-21 | 2026-06-04 |
| Optimal Morphine Dosing Schedule for Neonatal Abstinence Syndrome Morphine PRN, Morphine scheduled - Neonatal Abstinence Syndrome, Neonatal Opioid Withdrawal | Phase 4 | Completed | Indiana University | 17 | 2020-06-30 | 2022-10-06 |
| tAN to Mitigate Withdrawal Behaviors in Neonates Spark Biomedical Roo Transcutaneous Auricular Neurostimulation (tAN) System - Neonatal Abstinence Syndrome | Not applicable | Completed | Spark Biomedical, Inc. | 8 | 2020-05-30 | 2022-12-28 |
| MicroRNA Biomarkers for Neonatal Opioid Withdrawal Syndrome Buccal swab saliva for further genetic testing - Neonatal Opioid Withdrawal Syndrome, Neonatal Abstinence Syndrome | Recruiting | Milton S. Hershey Medical Center | 50 | 2020-01-15 | 2026-02-10 | |
| Assessing the Effects of Auricular Acupressure on Newborns With NAS Auricular acupressure - Neonatal Abstinence Syndrome | Not applicable | Completed | Virginia Commonwealth University | 12 | 2019-09-04 | 2021-04-13 |
| Feasibility of Auricular Acupressure as an Adjunct Treatment for Neonatal Abstinence Syndrome (NAS) Auricular acupuncture - Neonatal Abstinence Syndrome, Withdrawal | Not applicable | Completed | Vanderbilt University Medical Center | 12 | 2019-08-19 | 2020-03-10 |
| Maternal Opioid Treatment: Human Experimental Research - Data Yield Appropriate Decisions Medically-supervised withdrawal, Opioid agonist treatment, Comprehensive clinical care - Opioid-use Disorder, Opioid Withdrawal | Completed | University of Vermont | 88 | 2019-08-08 | 2024-02-08 |
Showing 20 of 68. Sign in to see all of them.
Opioid-Related Disorders (11) · Substance-Related Disorders (8) · Substance Withdrawal Syndrome (3) · Alcohol-Related Disorders (1) · Alcoholism (1) · Amphetamine-Related Disorders (1) · Bottle Feeding (1) · Chemically-Induced Disorders (1) · Cocaine-Related Disorders (1) · Hypoglycemia (1) · Hypoxia-Ischemia, Brain (1) · Infant, Newborn, Diseases (1) · Inhalant Abuse (1) · Marijuana Abuse (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (68) · Chemically-Induced Disorders (67) · Infant, Newborn, Diseases (67) · Mental Disorders (67) · Substance-Related Disorders (60) · Narcotic-Related Disorders (11) · Behavior (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Nervous System Diseases (2) · Aberrant Motor Behavior in Dementia (1) · Alcohol-Related Disorders (1) · Behavioral Symptoms (1) · Body Weight (1) · Body Weight Changes (1)
Morphine (14) · Buprenorphine (10) · Clonidine (8) · Methadone (7) · Buprenorphine, Naloxone Drug Combination (4) · Phenobarbital (4) · Actigraphy (2) · Acupuncture, Ear (2) · Acupuncture Therapy (1) · Chlorpromazine (1) · Drug Delivery Systems (1) · Fetal Monitoring (1) · Inactivation, Metabolic (1) · Maintenance (1) · Milk, Human (1)
Johns Hopkins University (6) · Thomas Jefferson University (4) · T. John Winhusen, PhD (3) · University Hospital, Caen (3) · Boston Medical Center (2) · Eastern Maine Medical Center (2) · Henrietta Bada (2) · Spark Biomedical, Inc. (2) · University of South Florida (2) · Baystate Medical Center (1) · Boston Children's Hospital (1) · Children's Hospital Medical Center, Cincinnati (1) · Dr. Henry Akinbi (1) · Elisabeth B Salisbury (1) · Elisabeth Salisbury, PhD (1)
United States (59) · France (3) · Canada (2) · United Kingdom (1)
Lauren M Jansson, MD (3) · T. John Winhusen, PhD (3) · Walter K Kraft, MD (3) · Elisabeth B Salisbury, Ph.D. (2) · Hendree E Jones, PhD (2) · Adam J Czynski, DO (1) · Aimee Telsey, MD (1) · Alexander Vinks, PharmD, PhD (1) · Alla Kushnir, MD (1) · Barry Lester, PhD (1) · Carrie Brusseau, PharmD (1) · Chloe Knox (1) · Christos Papadelis, PhD (1) · Cynthia Blanco, MD, MSCI-TS (1) · David R Drover, MD (1)
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