9 completed, 2 unknown, 1 active not recruiting, 1 terminated. 2 Not applicable, 1 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow Necrotizing Fasciitis: new trials by email Literature Review of Necrotizing Fasciitis trials Research Report on Necrotizing Fasciitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AFS Compared to AHC in Treatment of Necrotizing Fasciitis NF Acellular Fish Skin Graft (AFS) with Standard of Care Negative Pressure Wound Therapy (NPWT), Acellular Human Cadaver (AHC) with Standard of care Negative Pressure Wound Therapy (NPWT) - Necrotizing Fasciitis | Phase 4 | Active not recruiting | Kerecis Ltd. | 30 | 2023-08-01 | 2024-12-30 |
| SKin and Soft Tissue Necrotizing INfections in the Intensive Care Unit: a Prospective Multi-national Cohort Study non interventional - Necrotizing Fasciitis, Fournier Gangrene | Unknown | Henri Mondor University Hospital | 1033 | 2021-11-08 | 2021-11-23 | |
| RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft) - Full-thickness Skin Defects, Degloving Injuries | Not applicable | Completed | Avita Medical | 65 | 2020-03-02 | 2024-07-30 |
| Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections AB103 0.5 mg/kg, NaCl 0.9% - Necrotizing Soft Tissue Infections, Necrotizing Fasciitis | Phase 3 | Completed | Atox Bio Ltd | 290 | 2015-12-01 | 2021-10-05 |
| Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled Trial IVIG (Privigen), Saline 0.9% - Necrotizing Soft Tissue Infection, Necrotizing Fasciitis | Phase 2 | Completed | Anders Perner | 100 | 2014-04-01 | 2016-09-30 |
| Severe Soft Tissue Infections: Perspectives of Patients and Significant Others Necrotizing Fasciitis | Unknown | Göteborg University | 30 | 2014-01-01 | 2018-08-14 | |
| Biomarkers in Patients With Flesh-eating Bacterial Infections Necrotizing Soft Tissue Infection, Necrotizing Fasciitis | Completed | Ole Hyldegaard | 169 | 2013-02-01 | 2016-02-17 | |
| Modulation of Biomarkers in Patients With Flesh-eating Bacterial Infections After With Hyperbaric Oxygen Treatment Necrotizing Soft Tissue Infection, Necrotizing Fasciitis | Completed | Ole Hyldegaard | 65 | 2013-02-01 | 2019-06-24 | |
| Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs). Soft Tissue Infections, Necrotizing Fasciitis | Completed | Karolinska Institutet | 409 | 2013-01-01 | 2018-04-23 | |
| Coagulation and Fibrinolysis as Virulence Factors for Invasive Staphylococcus Aureus and Streptococcus Infections Infective Endocarditis, Necrotizing Fasciitis | Completed | Universitaire Ziekenhuizen KU Leuven | 89 | 2012-07-01 | 2023-09-05 | |
| Hyperglycemia in Surgical Infections Strict Glycemic control, Conventional Glycemic Control - Necrotizing Fasciitis | Not applicable | Terminated | The University of Texas Health Science Center, Houston | 5 | 2009-08-01 | 2018-11-21 |
| Klebsiella Pneumoniae Necrotizing Fasciitis: Clinical and Microbiological Features Necrotizing Fasciitis | Completed | National Taiwan University Hospital | 134 | 2009-07-01 | 2012-11-15 | |
| Outcome and Related Factors of Necrotizing Fasciitis of the Limb Necrotizing Fasciitis | Completed | Tehran University of Medical Sciences | 25 | 2007-09-01 | 2009-10-06 |
Fasciitis, Necrotizing (13) · Fournier Gangrene (5) · Gas Gangrene (3) · Soft Tissue Infections (3) · Fasciitis (2) · Infections (2) · Staphylococcal Infections (2) · Bacterial Infections (1) · Cellulitis (1) · Crush Injuries (1) · Degloving Injuries (1) · Disease (1) · Endocarditis (1) · Gangrene (1) · Necrosis (1)
Musculoskeletal Diseases (13) · Fasciitis (11) · Bacterial Infections and Mycoses (6) · Bacterial Infections (5) · Genital Diseases (5) · Genital Diseases, Male (5) · Infections (5) · Male Urogenital Diseases (5) · Urogenital Diseases (5) · Gram-Positive Bacterial Infections (4) · Clostridium Infections (3) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Skin Diseases (2) · Skin Diseases, Infectious (2)
Sodium Chloride (2) · AB103 (1) · Immunoglobulin G (1) · Immunoglobulins, Intravenous (1) · Saline Solution (1)
Ole Hyldegaard (2) · Anders Perner (1) · Atox Bio Ltd (1) · Avita Medical (1) · Göteborg University (1) · Henri Mondor University Hospital (1) · Karolinska Institutet (1) · Kerecis Ltd. (1) · National Taiwan University Hospital (1) · Tehran University of Medical Sciences (1) · The University of Texas Health Science Center, Houston (1) · Universitaire Ziekenhuizen KU Leuven (1)
Denmark (5) · United States (4) · France (2) · Sweden (2) · Belgium (1) · Iran (1) · Norway (1) · Taiwan (1)
Marco Bo Hansen, MD (2) · Ole Hyldegaard, MD, PhD (2) · Anders Perner, Professor (1) · Bounthavy Homsombath, MD (1) · Chi-Tai Fang, MD, PhD (1) · Eileen M Bulger, MD (1) · Lillian S Kao, MD (1) · Nicolas de Prost, MD, PhD (1) · Peter Verhamme, MD,PhD (1) · Ramin Espandar, MD (1) · Wayne M Dankner, MD (1)
PMID 31916575, PMID 25967993, PMID 26880104, PMID 27399982, PMID 28421246, PMID 32082310, PMID 32657946, PMID 34263738, PMID 36427229, PMID 37946314, PMID 38098145, PMID 39810178, PMID 40613866
K23RR020020 (1)