11 completed, 1 enrolling by invitation, 1 not yet recruiting, 1 recruiting. 1 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Fournier Gangrene: new trials by email Literature Review of Fournier Gangrene trials Research Report on Fournier Gangrene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Urinary Bladder Matrix (UBM) Registry Urinary Bladder Matrix (UBM) Products - Tissue Repair, Soft Tissue Reconstruction | Not yet recruiting | Integra LifeSciences Corporation | 300 | 2026-08-31 | 2026-09-04 | |
| Necrotizing Soft Tissue Infections Necrotizing Soft Tissue Infection, Fournier Gangrene | Enrolling by invitation | European Society for Trauma and Emergency Surgery | 480 | 2026-01-01 | 2025-08-06 | |
| The Immunological Differences Between Fournier Gangrene and Perianal Abscess Cytokine levels - Fournier Gangrene, Perianal Abscess | Completed | Istanbul Training and Research Hospital | 49 | 2022-01-01 | 2023-09-11 | |
| SKin and Soft Tissue Necrotizing INfections in the Intensive Care Unit: a Prospective Multi-national Cohort Study non interventional - Necrotizing Fasciitis, Fournier Gangrene | Unknown | Henri Mondor University Hospital | 1033 | 2021-11-08 | 2021-11-23 | |
| Fournier's Gangrene in Patient With Uncontrolled Type 2 Diabetes surgical debridement - Fournier Gangrene | Completed | University of Catania | 1 | 2020-11-04 | 2021-01-05 | |
| FATAL-NSTI Study (Factors Associated With In-hospital mortALity in NSTI). No Intervention: Observational Cohort - Necrotizing Fascitis, Fournier Gangrene | Recruiting | University of Cagliari | 300 | 2020-01-01 | 2026-01-22 | |
| Fournier's Gangrene and the Origin of the Infection as a Prognostic of Morbidity and Mortality, an Analysis of 121 Patients Aggressive debridement - Fournier Gangrene, Fournier's Gangrene of Penis | Completed | Hospital Universitario Dr. Jose E. Gonzalez | 121 | 2017-11-01 | 2018-02-23 | |
| Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections AB103 0.5 mg/kg, NaCl 0.9% - Necrotizing Soft Tissue Infections, Necrotizing Fasciitis | Phase 3 | Completed | Atox Bio Ltd | 290 | 2015-12-01 | 2021-10-05 |
| Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled Trial IVIG (Privigen), Saline 0.9% - Necrotizing Soft Tissue Infection, Necrotizing Fasciitis | Phase 2 | Completed | Anders Perner | 100 | 2014-04-01 | 2016-09-30 |
| Biomarkers in Patients With Flesh-eating Bacterial Infections Necrotizing Soft Tissue Infection, Necrotizing Fasciitis | Completed | Ole Hyldegaard | 169 | 2013-02-01 | 2016-02-17 | |
| Prognosis and Treatment of Necrotizing Soft Tissue Infections: A Prospective Cohort Study Hyperbaric oxygen therapy - Necrotizing Soft Tissue Infection, Necrotizing Fascitis | Completed | Ole Hyldegaard | 260 | 2013-02-01 | 2019-06-24 | |
| Modulation of Biomarkers in Patients With Flesh-eating Bacterial Infections After With Hyperbaric Oxygen Treatment Necrotizing Soft Tissue Infection, Necrotizing Fasciitis | Completed | Ole Hyldegaard | 65 | 2013-02-01 | 2019-06-24 | |
| Management of Fournier Gangrene at Ibn Rochd University Hospital Center Necrotesectomy associated with cleanleness stoma - Fournier Gangrene | Completed | Sylvestre KABURA | 84 | 2010-01-01 | 2021-07-30 | |
| Daptomycin for the Treatment of Severe Necrotizing Soft-Tissue Infections Daptomycin 6mg/kg/day - Fasciitis, Necrotizing, Severe Necrotizing Skin and Soft Tissue Infections | Not applicable | Completed | University of Maryland, Baltimore | 25 | 2005-06-01 | 2022-01-27 |
| Exploratory Study of Raised Serum Lactate as a Marker of Necrotizing Fasciitis Fasciitis, Necrotizing | Completed | National Health Service, United Kingdom | 53 | 2000-09-01 | 2012-12-04 |
Fasciitis, Necrotizing (9) · Soft Tissue Infections (6) · Gas Gangrene (4) · Disease (3) · Fasciitis (3) · Gangrene (3) · Infections (3) · Bacterial Infections (2) · Necrosis (2) · Skin Diseases, Bacterial (2) · Staphylococcal Infections (2) · Wounds and Injuries (2) · Cellulitis (1) · Diabetes Mellitus, Type 2 (1)
Bacterial Infections and Mycoses (15) · Genital Diseases (15) · Genital Diseases, Male (15) · Male Urogenital Diseases (15) · Urogenital Diseases (15) · Bacterial Infections (13) · Infections (12) · Musculoskeletal Diseases (9) · Fasciitis (6) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Clostridium Infections (4) · Gram-Positive Bacterial Infections (4) · Skin Diseases, Infectious (4) · Skin and Connective Tissue Diseases (4)
Sodium Chloride (2) · AB103 (1) · Daptomycin (1) · Hyperbaric Oxygenation (1) · Immunoglobulin G (1) · Immunoglobulins, Intravenous (1) · Saline Solution (1)
Ole Hyldegaard (3) · Anders Perner (1) · Atox Bio Ltd (1) · European Society for Trauma and Emergency Surgery (1) · Henri Mondor University Hospital (1) · Hospital Universitario Dr. Jose E. Gonzalez (1) · Integra LifeSciences Corporation (1) · Istanbul Training and Research Hospital (1) · National Health Service, United Kingdom (1) · Sylvestre KABURA (1) · University of Cagliari (1) · University of Catania (1) · University of Maryland, Baltimore (1)
Denmark (4) · France (2) · Italy (2) · United States (2) · Mexico (1) · Spain (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Ole Hyldegaard, MD, PhD (3) · Marco Bo Hansen, MD (2) · Adolfo Pisanu, MD (1) · Anders Perner, Professor (1) · Eileen M Bulger, MD (1) · Gary A Bass, MD PhD (1) · George Murphy, MRCS (1) · Manjari G Joshi, MD (1) · Nicolas de Prost, MD, PhD (1) · Peter V Polzik, MD (1) · Wayne M Dankner, MD (1)
PMID 25967993, PMID 26880104, PMID 27399982, PMID 28421246, PMID 28982834, PMID 31916575, PMID 32082310, PMID 32657946