16 completed. 16 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Completed 16 |
Follow Necrotizing Enterocolitis: new trials by email Literature Review of Necrotizing Enterocolitis trials Research Report on Necrotizing Enterocolitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Effectiveness Trial for Diagnosis of Necrotizing Enterocolitis Bowel Ultrasound, Abdominal radiograph - Necrotizing Enterocolitis | Not applicable | Completed | Children's Mercy Hospital Kansas City | 169 | 2022-11-01 | 2025-11-21 |
| Cohort of Premature Newborns for Charaterization of the Digestive Microbiota in Ulcerative Necrotizing Enterocolitis in Premature Infants premature newborns developing a NEC, premature newborns without NEC - Necrotizing Enterocolitis, Premature Birth | Not applicable | Completed | University Hospital, Clermont-Ferrand | 297 | 2021-07-02 | 2026-09-10 |
| The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery. SPY imaging, Indocyanine Green - Intestinal Atresia, Necrotizing Enterocolitis | Not applicable | Completed | St. Justine's Hospital | 35 | 2020-03-16 | 2021-03-17 |
| Early Routine vs. Selective Human Milk Fortification in Extremely Preterm Infants Routine vs Selective use of Human Milk Donor Fortifier - Poor Growth in Extremely Preterm Infants, Necrotizing Enterocolitis | Not applicable | Completed | Crouse Hospital | 170 | 2020-02-15 | 2026-04-30 |
| Bovine Colostrum as a Human Milk Fortifier for Preterm Infants Bovine Colostrum, FM85 - Feeding Intolerance, Necrotizing Enterocolitis | Not applicable | Completed | Per Torp Sangild | 139 | 2019-05-01 | 2022-01-28 |
| Bovine Colostrum as a Fortifier Added to Human Milk for Preterm Infants Bovine Colostrum (BC) / intervention group, FM85 / control group - Growth, Necrotizing Enterocolitis | Not applicable | Completed | Per Torp Sangild | 252 | 2017-12-04 | 2022-03-23 |
| Bovine Colostrum for Preterm Newborns Bovine Colostrum, Preterm Formula - Enteral Feeding Intolerance, Necrotizing Enterocolitis | Not applicable | Completed | Per Torp Sangild | 350 | 2017-07-01 | 2022-07-12 |
| MISA to NRDS：a Multicenter Study in China Minimal Invasive surfactant administration - Bronchopulmonary Dysplasia, Patent Ductus Arteriosus | Not applicable | Completed | Peking University Third Hospital | 237 | 2017-07-01 | 2019-09-06 |
| Pilot Study of the Feasibility of Feeding Preterm Infants With Fresh Versus Frozen Mother's Own Breast Milk in the NICU Fresh Milk - Necrotizing Enterocolitis | Not applicable | Completed | Huiqing Sun | 100 | 2016-01-01 | 2018-09-05 |
| PREMAPROB. Probiotics to Prevent Necrotizing Enterocolitis High dose group, Low dose group - Premature Infants, Necrotizing Enterocolitis | Not applicable | Completed | José Antonio Hurtado Suazo | 583 | 2015-01-10 | 2024-07-15 |
| Feeding Bovine Colostrum to Preterm Infants Bovine colostrum - Feeding Intolerance, Extrauterine Growth Retardation | Not applicable | Completed | Per Torp Sangild | 52 | 2014-02-01 | 2019-01-22 |
| Speed of Increasing Milk Feeds Trial Milk feed (breast milk or formula milk) - Premature Birth, Late-onset Invasive Infection | Not applicable | Completed | University of Oxford | 2804 | 2013-06-01 | 2019-03-11 |
| Effects of Oral Probiotic Supplementation on the Clinical Status of Very-low-birth-weight Preterm Neonates. Probiotic, Placebo - Late Onset Neonatal Sepsis, Necrotizing Enterocolitis | Not applicable | Completed | IBSS Biomed S.A. | 182 | 2012-04-01 | 2014-02-27 |
| Collaborative Research Group for Necrotizing Enterocolitis [5,5,5-2H3]leucine (stable isotope labeled leucine) - Prematurity, Necrotizing Enterocolitis | Not applicable | Completed | Washington University School of Medicine | 29 | 2008-05-01 | 2018-04-04 |
| Comparison of Two Surgical Treatments for Necrotizing Enterocolitis in Human Infants laparotomy, primary peritoneal drainage - Necrotizing Enterocolitis | Not applicable | Completed | Yale University | 130 | 1999-07-01 | 2006-07-21 |
| Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants Fortified Pasteurized Donor Human Milk supplement, Preterm Formula supplement - Necrotizing Enterocolitis, Sepsis | Not applicable | Completed | National Center for Research Resources (NCRR) | 300 | 1997-01-01 | 2005-06-24 |
Enterocolitis, Necrotizing (16) · Premature Birth (5) · Neonatal Sepsis (3) · Sepsis (3) · Bronchopulmonary Dysplasia (1) · Communicable Diseases (1) · Ductus Arteriosus, Patent (1) · Enterocolitis (1) · Gastrointestinal Diseases (1) · Gastroschisis (1) · Hirschsprung Disease (1) · Immune System Diseases (1) · Infant, Newborn, Diseases (1) · Intestinal Atresia (1) · Intestinal Obstruction (1)
Digestive System Diseases (16) · Gastroenteritis (16) · Intestinal Diseases (16) · Enterocolitis (15) · Gastrointestinal Diseases (15) · Pathological Conditions, Signs and Symptoms (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Infections (6) · Inflammation (6) · Pathologic Processes (6) · Systemic Inflammatory Response Syndrome (6) · Female Urogenital Diseases and Pregnancy Complications (5) · Obstetric Labor Complications (5) · Obstetric Labor, Premature (5) · Pregnancy Complications (5)
Control Groups (1) · Food (1) · Indocyanine Green (1) · Laparotomy (1) · Milk, Human (1) · Population Groups (1) · Probiotics (1)
Per Torp Sangild (4) · Children's Mercy Hospital Kansas City (1) · Crouse Hospital (1) · Huiqing Sun (1) · IBSS Biomed S.A. (1) · José Antonio Hurtado Suazo (1) · National Center for Research Resources (NCRR) (1) · Peking University Third Hospital (1) · St. Justine's Hospital (1) · University Hospital, Clermont-Ferrand (1) · University of Oxford (1) · Washington University School of Medicine (1) · Yale University (1)
China (5) · United States (5) · Denmark (2) · Canada (1) · France (1) · Ireland (1) · Spain (1) · United Kingdom (1)
Aaron Hamvas, MD (1) · Aleksandra M Cichonska, PhD (1) · Bouraa Bou Aram, MD (1) · Gitte Zachariassen, MD., PhD (1) · Jon Dorling, MBChB DCH MD (1) · Per Sangild, PhD (1) · Per Sangild, Prof (1) · Per T Sangild (1) · Per T. Sangild, PhD (1) · Ping Zhou (1) · R. Lawrence Moss, MD (1) · Richard J. Schanler (1) · Ryszard Lauterbach, Prof., MD (1) · Sherwin Chan, MD, PhD (1)
PMID 16723614, PMID 29019855, PMID 30700726, PMID 31118098, PMID 37437359, PMID 37565393, PMID 38587119, PMID 39581179, PMID 39982063