21 completed, 18 unknown, 11 recruiting, 8 not yet recruiting. 23 Not applicable, 2 Phase 2, 2 Phase 3, 2 Phase 4, 1 Early Phase 1.
Follow Hirschsprung Disease: new trials by email Literature Review of Hirschsprung Disease trials Research Report on Hirschsprung Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Butyrate Enemas on Postoperative Intestinal Motility Disorders in Hirschsprung's Disease Sodium Butyrate, routine management - Hirschsprung's Disease | Phase 3 | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 58 | 2026-11-01 | 2026-09-10 |
| Comparison of a New Non-invasive Device With the Invasive Gold-standard Investigation to Assess Function of the Large Bowel in Children Body Surface Colonic Mapping - Bowel Dysfunction, Dysmotility | Not applicable | Not yet recruiting | Murdoch Childrens Research Institute | 50 | 2026-09-01 | 2026-09-02 |
| Urinary and Sexual Symptoms in Patients With Hirschsprung Disease Type of pull-through procedure performed as part of routine clinical care (Swenson, Duhamel, or Soave). - Hirschsprung Disease | Not yet recruiting | University Hospital, Grenoble | 556 | 2026-08-01 | 2026-08-03 | |
| Pattern And Outcome Of Neonatal Gastrointestinal Emergencies In Assiut University Children Hospital Necrotizing Enterocolitis, Intestinal Atresia | Not yet recruiting | Assiut University | 120 | 2026-05-01 | 2026-04-13 | |
| Surgical Approach for the Treatment of Hirschsprung Disease Using the Swenson Technique (SMILES) transanal or laparoscopy assisted Swenson coloanal pullthrough - Hirschsprung Disease | Not yet recruiting | University Hospital, Angers | 70 | 2026-03-01 | 2026-03-12 | |
| Robot/Laparoscopic-Assisted Transanal Transection Duhamel Versus Modified Soave Pull-Through for TCA Transanal Transection Duhamel operation, Modified Soave Pull-Through - Total Colonic Aganglionosis, Hirschsprung Disease | Not applicable | Not yet recruiting | Zunyi Medical College | 50 | 2026-01-30 | 2026-01-15 |
| Effects of Physiotherapy in Children With Hirschsprung's Disease Physiotherapy - Hirschsprung Disease | Not applicable | Not yet recruiting | Ankara Yildirim Beyazıt University | 20 | 2025-09-30 | 2025-09-05 |
| Long-Term Health Outcomes in Children Born With Hirschsprung's Disease and Anorectal Malformations at the Colorectal Centre of Excellence in Quebec No intervention (observational study) - Anorectal Malformation, Hirschprung's Disease | Enrolling by invitation | McGill University Health Centre/Research Institute of the McGill University Health Centre | 999 | 2025-08-26 | 2026-05-22 | |
| MSOT and MRI for Non-invasive Assessment of Intestinal Transit Time in Children With Chronic Bowel Emptying Disorders MSOT with ICG, MRI - Chronic Constipation, Slow Transit Constipation | Not applicable | Recruiting | Dr. med. Sonja Diez | 20 | 2025-04-15 | 2025-09-03 |
| Babies With Enterocolitis - A Study of Faecal Calprotectin in Hirschsprung Disease (The BEACH Study) Hirschprung's Disease, Hirschsprung Disease | Not yet recruiting | Alder Hey Children's NHS Foundation Trust | 50 | 2024-10-01 | 2024-09-19 | |
| Institutional Registry of Rare Diseases Rare Diseases, Amyloidosis | Recruiting | Hospital Italiano de Buenos Aires | 380 | 2024-07-01 | 2026-01-14 | |
| Hirschsprung's Advances; Working Towards Autologous tIssue therapIes Observational study of tissue specimens - Hirschsprung Disease | Recruiting | Alder Hey Children's NHS Foundation Trust | 300 | 2024-03-05 | 2024-09-19 | |
| Impact of Providing Nursing Support on Parental Stress Related to Preoperative Care of a Newborn with Hirschsprung's Disease Pediatric HAH - Hirschsprung Disease | Not applicable | Recruiting | Assistance Publique Hopitaux De Marseille | 20 | 2023-08-14 | 2024-10-21 |
| The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies Standard of Care, Exclusive Human Milk - Gastrointestinal Complication, Intestinal Obstruction | Not applicable | Recruiting | Seattle Children's Hospital | 116 | 2023-06-09 | 2026-04-30 |
| Risk Factors for Bowel Dysfunction at Preschool and Early Childhood Age in Children With Hirschsprung Disease bowel function score(BFS) questionnaire survey - Bowel Dysfunction, Hirschsprung Disease | Unknown | Weibing Tang | 300 | 2022-08-20 | 2023-08-23 | |
| The Long Term Outcomes After Pull-through of Long Segment Hirschsprung Disease questionnaire survey - Constipation, Incontinence | Unknown | Weibing Tang | 50 | 2022-07-15 | 2022-12-01 | |
| Neokare Safety and Tolerability Assessment in Neonates With GI Problems NeoKare Breast Milk Fortifier - NEC, Gastroschisis | Unknown | University Hospital Southampton NHS Foundation Trust | 50 | 2022-06-09 | 2022-10-28 | |
| Induced Pluripotent Stem Cells for Disease Research Hirschsprung Disease | Completed | University of California, San Francisco | 1 | 2022-04-15 | 2022-10-06 | |
| Long-term Qualitative and Quantitative Outcomes of Children With Hirschsprung's Disease and Anorectal Malformations Pull through - Hirschsprung Disease, Anorectal Malformations | Recruiting | Alder Hey Children's NHS Foundation Trust | 1200 | 2022-01-25 | 2024-01-30 | |
| Full Thickness vs. Rectal Suction Biopsy in the Diagnosis of Hirschsprungs Disease Rectal suction biopsy., Full-thickness rectal biopsy. - Hirschsprung Disease | Not applicable | Unknown | University of Southern Denmark | 300 | 2022-01-01 | 2022-05-17 |
Showing 20 of 61. Sign in to see all of them.
Anorectal Malformations (9) · Constipation (5) · Gastroschisis (5) · Enterocolitis (4) · Intestinal Atresia (4) · Intestinal Obstruction (4) · Enterocolitis, Necrotizing (3) · Hernia, Umbilical (3) · Intestinal Volvulus (3) · Volvulus Of Midgut (3) · Inflammatory Bowel Diseases (2) · Intestinal Diseases (2) · Intestinal Perforation (2) · Meconium Ileus (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (61) · Digestive System Abnormalities (61) · Digestive System Diseases (61) · Gastrointestinal Diseases (61) · Megacolon (61) · Colonic Diseases (60) · Congenital Abnormalities (60) · Intestinal Diseases (59) · Pathological Conditions, Signs and Symptoms (16) · Gastroenteritis (9) · Signs and Symptoms (9) · Pathological Conditions, Anatomical (8) · Musculoskeletal Abnormalities (6) · Musculoskeletal Diseases (6) · Signs and Symptoms, Digestive (6)
Endoscopic Mucosal Resection (2) · Indocyanine Green (2) · Probiotics (2) · Surveys and Questionnaires (2) · Butyric Acid (1) · Conservative Treatment (1) · Ileostomy (1) · Immunohistochemistry (1) · Lactulose (1) · Mineral Oil (1) · Observation (1) · Physical Therapy Modalities (1) · Self Care (1) · Standard of Care (1)
Tongji Hospital (4) · Alder Hey Children's NHS Foundation Trust (3) · Assistance Publique Hopitaux De Marseille (3) · University of Southern Denmark (3) · Weibing Tang (3) · Assiut University (2) · Friedrich-Alexander-Universität Erlangen-Nürnberg (2) · Massachusetts General Hospital (2) · National Children's Hospital, Vietnam (2) · St. Justine's Hospital (2) · University Hospital, Angers (2) · Zunyi Medical College (2) · Al-Azhar University (1) · Ankara Yildirim Beyazıt University (1) · Aswan University Hospital (1)
United States (11) · China (7) · France (7) · Canada (4) · Denmark (4) · United Kingdom (4) · Egypt (3) · Germany (3) · Netherlands (2) · Vietnam (2) · Argentina (1) · Australia (1) · Belgium (1) · Ethiopia (1) · Norway (1)
Quang T Nguyen, M.D. (2) · Adrian Gadano, MD (1) · Adrian Regensburger, PD Dr. med. (1) · Andreana Butter, MD (1) · Aravinda Chakravarti, PhD (1) · Braden Kuo, M.D. (1) · Braden Kuo, MD (1) · Changgui Lu, Dr (1) · Clarissa Foy, NP (1) · Daniel H Teitelbaum, MD (1) · Debra E Weese-Mayer, MD (1) · Eduardo Jorge Premoli, MD (1) · Enrique Freud, MD (1) · Field F Willingham, MD, MPH (1)
PMID 15660319, PMID 20717739, PMID 26611332, PMID 33395367, PMID 34059040, PMID 11953745, PMID 13403593, PMID 14497096, PMID 15829955, PMID 19306335, PMID 20598273, PMID 23331802, PMID 25666438, PMID 25909773, PMID 26386879, PMID 26561246, PMID 27693352, PMID 28169931, PMID 29602547, PMID 30964819, PMID 31481373, PMID 31535199, PMID 31676258, PMID 32063371, PMID 32068552, PMID 33877661, PMID 35622006, PMID 35847080, PMID 35941653, PMID 37398887, PMID 37851500, PMID 37865736, PMID 38195486, PMID 38515199, PMID 39819595, PMID 40634926, PMID 41419466, PMID 42218492, PMID 42467022, PMID 42664155
2018 (1), 2025 (1)