20 completed, 19 unknown, 12 active not recruiting, 7 not yet recruiting. 41 Not applicable, 9 Phase 3, 7 Phase 2, 5 Phase 1, 1 Early Phase 1.
Follow Myopia, Degenerative: new trials by email Literature Review of Myopia, Degenerative trials Research Report on Myopia, Degenerative
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Retinal Clinical Assessment With AI-derived Quantitative Information AI-derived retinal quantitative information-assisted reporting - no Obvious Abnormalities, Diabetic Retinopathy (DR) | Not yet recruiting | Beijing Tongren Hospital | 29 | 2026-04-15 | 2026-04-29 | |
| Efficacy of Different Interventions for Progressive Myopia After Orthokeratology Lens Wear OK Lens Continuation Group, OK Lens + 0.01% Atropine Group, OK Lens with Reduced Optical Zone Group - Progressive Myopia, Pediatric Myopia | Not yet recruiting | Tianjin Medical University Eye Hospital | 3890 | 2026-04-01 | 2026-04-01 | |
| Evaluation of the Safety and Efficacy of the D.D.C Dual-control Technology Spectacle Lenses in Delaying the Progression of Myopia: a Randomized Controlled Trial D.D.C dual-control technology spcetacle lenses, Aspheric single-vision lenses - Myopia, Progressive | Not applicable | Active not recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 316 | 2026-03-23 | 2026-07-28 |
| Multicenter RCT: LED Red Light Dose-Response in Myopia Progression Control Yingtong Vision Rehabilitation Instrument, Hoya DIMS multi-point myopia defocus lens - Myopia, Myopia, Progressive | Not applicable | Not yet recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 364 | 2026-01-01 | 2026-01-09 |
| Myopia Progression With Freeform Myopia Control Spectacles freeform myopia control spectacles, Commercial myopia control spectacle lens (CML) - Myopia, Progressive | Not applicable | Active not recruiting | Shanghai Eye Disease Prevention and Treatment Center | 180 | 2025-05-17 | 2025-12-08 |
| An Interpretable Fundus Diseases Report Generating System Based On Weakly Labelings With fundus diseases, Without fundus diseases - Retinal Diseases, Choroidal Disease | Not yet recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 9999 | 2025-05-01 | 2025-04-09 | |
| Impact of Digital Screen Time in Progression of Myopia in Children Progression of Myopia - Myopia, Progressive | Active not recruiting | Superior University | 79 | 2025-03-17 | 2025-07-09 | |
| Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children. Alleance®, Placebo - Myopia, Myopia, Progressive | Phase 3 | Recruiting | Laboratorios Sophia S.A de C.V. | 123 | 2025-03-15 | 2025-03-21 |
| Atropine Alone vs Atropine Plus Bifocal Spectacles for Myopia Control in Children Atropine Sulfate 0.05% Ophthalmic Solution, Bifocal Spectacles - Myopia, Progressive Myopia | Not applicable | Completed | University of Faisalabad | 210 | 2025-02-17 | 2026-05-29 |
| A Study of SHJ002 Sterile Ophthalmic Solution for Myopia Control SHJ002, Atropine - Myopia, Progressive | Phase 2 | Active not recruiting | Sunhawk Vision Biotech, Inc. | 140 | 2025-01-22 | 2026-01-23 |
| A Unified Index to Predict the Success Probability of Myopia Control orthokeratology lens, multifocal soft contact lens, Single vision spectacles - Myopia, Progressive | Not applicable | Withdrawn | Nova Southeastern University | 2025-01-01 | 2023-09-13 | |
| Safety and Efficacy of Blue Star MAX-5 Lenses in Myopia Control Blue star MAX-5 spectacle lens, Single-vision spectacle lens - Myopia, Progressive | Not applicable | Active not recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 200 | 2024-11-01 | 2026-03-12 |
| Stellest Lens Wear in Adult Progressing Myopes Essilor® Stellest® spectacle lens, Single-vision spectacle lens - Myopia, Progressive | Not applicable | Active not recruiting | University of Ulster | 42 | 2024-10-17 | 2026-02-19 |
| Novel Lenses for Myopia Progression Trial spectacle lens, single vision lens - Myopia, Progressive | Not applicable | Active not recruiting | Shanghai Eye Disease Prevention and Treatment Center | 342 | 2024-08-16 | 2026-04-28 |
| Predictors of Vitrectomy Outcomes in Myopic Foveoschisis pars plana vitrectomy - Myopic Traction Maculopathy | Not applicable | Recruiting | Singapore National Eye Centre | 30 | 2024-06-10 | 2026-08-19 |
| Efficacy and Safety of 0.01%, 0.03%, and 0.05% Atropine Eye Drops in Reducing Myopia Progression Atropine sulphate eye drop 0.01%, Atropine sulphate eye drop 0.03%, Atropine sulphate eye drop 0.05% - Myopia Progression, Atropine | Phase 3 | Completed | Khyber Medical College, Peshawar | 95 | 2024-06-03 | 2026-06-10 |
| To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia frame lens - Myopia, Progressive | Not applicable | Not yet recruiting | Tianjin Eye Hospital | 138 | 2024-05-01 | 2024-05-08 |
| Differences and Wearing Safety and Comfort of New Defocus Incorporated Multiple Segments Spectacle Lenses defocus spectacle lenses - Myopia, Progressive | Not applicable | Enrolling by invitation | Shanghai Eye Disease Prevention and Treatment Center | 252 | 2024-03-01 | 2024-10-01 |
| Efficacy of IVMED-85 on Pediatric Myopia IVMED 85, Placebo - Myopia, Progressive | Phase 1 / Phase 2 | Not yet recruiting | iVeena Delivery Systems, Inc. | 216 | 2024-02-01 | 2023-09-29 |
| Management of Myopia in University Students Using Dual Focus Soft Contact Lenses MiSight contact lenses, Proclear contact lenses - Myopia, Progressive | Not applicable | Enrolling by invitation | University of Bradford | 84 | 2024-01-01 | 2026-06-23 |
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Myopia (26) · Choroidal Neovascularization (7) · Refractive Errors (5) · Diabetic Retinopathy (3) · Eye Diseases (3) · Macular Degeneration (3) · Choroid Diseases (2) · Polypoidal Choroidal Vasculopathy (2) · Retinal Diseases (2) · Retinal Perforations (2) · Vision Disorders (2) · Astigmatism (1) · Epiretinal Membrane (1) · Hypersensitivity (1)
Eye Diseases (66) · Refractive Errors (64) · Myopia (43) · Pathological Conditions, Signs and Symptoms (10) · Uveal Diseases (10) · Metaplasia (9) · Neovascularization, Pathologic (9) · Pathologic Processes (9) · Choroid Diseases (8) · Retinal Diseases (5) · Cardiovascular Diseases (4) · Retinal Degeneration (4) · Vascular Diseases (4) · Diabetes Complications (3) · Diabetes Mellitus (3)
Atropine (5) · Ranibizumab (5) · Ophthalmic Solutions (4) · Bevacizumab (1) · Eyeglasses (1) · Low-Level Light Therapy (1) · Photochemotherapy (1) · aflibercept (1) · fosbretabulin (1)
Shanghai Eye Disease Prevention and Treatment Center (7) · Beijing Airdoc Technology Co., Ltd. (4) · Tianjin Eye Hospital (4) · Zhongshan Ophthalmic Center, Sun Yat-sen University (4) · Menicon Co., Ltd. (3) · Novartis Pharmaceuticals (2) · Aller, Thomas A., OD (1) · Bayer (1) · Beijing Tongren Hospital (1) · Biotech Healthcare Holding Gmbh (1) · Centre Hospitalier Intercommunal Creteil (1) · Chang Gung Memorial Hospital (1) · Cloudbreak Therapeutics, LLC (1) · Erasmus Medical Center (1) · Essilor International (1)
China (24) · United States (9) · Singapore (4) · Taiwan (4) · United Kingdom (4) · Germany (3) · Pakistan (3) · South Korea (3) · Australia (2) · Canada (2) · France (2) · Hong Kong (2) · India (2) · Italy (2) · Japan (2)
Jian Ge (2) · Thomas A Aller, OD (2) · Xiaoqin Chen, MD (2) · Andrew Tan (1) · Andrew Tsai, MD (1) · Anuradha Ganesh, MD (1) · Flavia Chiosi, MD (1) · Gregory Ostrow, MD (1) · Haidong Zou (1) · He Xiangui (1) · Hong Liu, MD, PHD (1) · Jill Woods, BSc, MCOptom (1)
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2009 (1)