9 completed, 4 unknown, 3 withdrawn, 2 terminated. 6 Not applicable, 3 Phase 1, 3 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Terminated 1, Unknown 1 |
| Phase 1 | 3 | Completed 1, Unknown 1, Withdrawn 1 |
| Phase 4 | 3 | Completed 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Myocardial Stunning: new trials by email Literature Review of Myocardial Stunning trials Research Report on Myocardial Stunning
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intradialytic Exercise and Remote Ischaemic Preconditioning: a Cardioprotective Role ? Remote ischaemic preconditioning, Exercise, standard dialysis - Hemodialysis | Not applicable | Completed | University of Avignon | 33 | 2025-02-17 | 2026-04-29 |
| Safety and Feasibility of Hyperkalemic Cardioplegia With Diazoxide in Cardiac Surgery (CPG-DZX) Trial IV Diazoxide - Myocardial Stunning | Phase 1 | Completed | Johns Hopkins University | 30 | 2024-07-08 | 2025-07-14 |
| Safety and Efficacy of IV Diazoxide as an Additive to Hyperkalemic Cardioplegia in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass IV Diazoxide, Placebo - Myocardial Stunning | Phase 1 | Withdrawn | Johns Hopkins University | 2023-09-01 | 2022-09-19 | |
| Novel Imaging Biomarkers for Mechanical Complications in Acute Myocardial Infarction Acute Myocardial Infarction, Hemorrhagic Myocardial Infarction | Completed | Rohan Dharmakumar | 250 | 2022-06-01 | 2026-01-14 | |
| Co-transplantation of Mesenchymal Stem Cell Derived Exosomes and Autologous Mitochondria for Patients Candidate for CABG Surgery mitochondria and MSC-derived exosomes - Myocardial Infarction, Myocardial Ischemia | Phase 1 / Phase 2 | Unknown | Tehran University of Medical Sciences | 20 | 2022-04-20 | 2022-12-30 |
| Is Myocardial Stunning Induced by Continuous Renal Replacement Therapy a Reality in Critically Ill Patients? Continuous renal replacement therapy, Control group - Acute Kidney Injury KDIGO 3, Continuous Renal Replacement Therapy Initiated by the Clinician in Charge Without Emergency | Not applicable | Completed | Hospices Civils de Lyon | 42 | 2022-04-15 | 2026-01-08 |
| Pre- or Per-dialytic Physical Exercise : a Cardioprotective Role? Dialysis without physical exercise, Dialysis with pre-dialytic physical exercise, Dialysis with per-dialytic physical exercise - Chronic Kidney Diseases | Not applicable | Unknown | University Hospital, Montpellier | 32 | 2021-09-24 | 2022-01-04 |
| STunning After Balloon Occlusion Intracoronary balloon inflation - Coronary Artery Disease | Not applicable | Terminated | Vastra Gotaland Region | 6 | 2021-09-06 | 2026-06-02 |
| Stunning in Takotsubo Versus Acute Myocardial Infarction Echocardigraphy (ECHO), Bloodtest - Myocardial Stunning | Recruiting | Vastra Gotaland Region | 125 | 2019-12-12 | 2023-12-12 | |
| Rate of Left Ventricular Systolic Function's Recuperation After Cardiac Surgery With Extracorporeal Circulation. Imacor - Myocardial Stunning, Transesophageal Echocardiography | Withdrawn | University Hospital, Geneva | 2019-12-01 | 2022-06-01 | ||
| Ranolazine a Potential New Therapeutic Application Ranolazine, Placebo - Myocardial Stunning | Phase 4 | Withdrawn | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2019-04-10 | 2021-02-25 | |
| Cardiomyocyte Injury Following Acute Ischemic Stroke Stroke, Ischemic, Cardiac Complication | Unknown | Charite University, Berlin, Germany | 300 | 2019-04-01 | 2024-02-20 | |
| Intracoronary Administration of Levosimendan in Cardiac Surgery Patients levosimendan, Vitamin B 12 - Myocardial Stunning | Phase 4 | Terminated | Tampere University Hospital | 50 | 2018-06-15 | 2019-09-13 |
| The Success of Opening Single CTO Lesions to Improve Myocardial Viability Study (SOS-comedy) stenting or balloon expansion, aspirin, clopidogrel, ticagrelor, atorvastatin, rosuvastatin, betaloc - Hibernation, Myocardial, Complete Occlusion of Coronary Artery | Phase 4 | Completed | The First Affiliated Hospital of Dalian Medical University | 200 | 2015-09-15 | 2019-03-19 |
| Myocardial Stunning During Hemodialysis: Role of Dialyste Calcium Concentration Change the dialysate calcium concentration - Myocardial Stunning, End-stage Renal Disease | Not applicable | Completed | University of Sao Paulo General Hospital | 19 | 2015-07-01 | 2019-03-14 |
| Exercise-induced Changes in Cardiac Function & Morphology Strenuous Endurance exercise - Myocardial Ischemia, Exercise | Not applicable | Completed | Insel Gruppe AG, University Hospital Bern | 11 | 2010-07-01 | 2011-02-15 |
| Serial Echocardiography After Subarachnoid Hemorrhage Subarachnoid Hemorrhage, Myocardial Stunning | Unknown | Amsterdam UMC, location VUmc | 350 | 2005-05-01 | 2008-03-27 | |
| Evaluation of Myocardial Viability by Means of Low-dose Dobutamine Gated SPECT (the DOGS Study) Coronary Arteriosclerosis, Heart Failure, Congestive | Completed | University Hospital, Rouen | 75 | 2003-10-01 | 2013-06-18 | |
| Analysis of Heart Muscle Function Following Exercise in Patients With Heart Disease Healthy | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 80 | 1996-02-01 | 2008-03-04 |
Coronary Artery Disease (4) · Motor Activity (3) · Myocardial Ischemia (3) · Heart Failure (2) · Myocardial Infarction (2) · Acute Coronary Syndrome (1) · Acute Kidney Injury (1) · Cardiovascular Diseases (1) · Heart Rupture, Post-Infarction (1) · Ischemic Stroke (1) · Kidney Failure, Chronic (1) · Myocardial Reperfusion Injury (1) · Renal Insufficiency, Chronic (1) · Stroke (1)
Heart Diseases (19) · Pathological Conditions, Signs and Symptoms (19) · Signs and Symptoms (19) · Cardiovascular Diseases (18) · Vascular Diseases (9) · Pathologic Processes (6) · Myocardial Ischemia (5) · Arterial Occlusive Diseases (4) · Arteriosclerosis (4) · Coronary Disease (4) · Behavior (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Kidney Diseases (3) · Male Urogenital Diseases (3)
Diazoxide (2) · Exercise (2) · Aspirin (1) · Atorvastatin (1) · Clopidogrel (1) · Continuous Renal Replacement Therapy (1) · Control Groups (1) · Dialysis (1) · Genes, Mitochondrial (1) · Metoprolol (1) · Percutaneous Coronary Intervention (1) · Ranolazine (1) · Rosuvastatin Calcium (1) · Simendan (1) · Stents (1)
Johns Hopkins University (2) · Vastra Gotaland Region (2) · Amsterdam UMC, location VUmc (1) · Charite University, Berlin, Germany (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Hospices Civils de Lyon (1) · Insel Gruppe AG, University Hospital Bern (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Rohan Dharmakumar (1) · Tampere University Hospital (1) · Tehran University of Medical Sciences (1) · The First Affiliated Hospital of Dalian Medical University (1) · University Hospital, Geneva (1) · University Hospital, Montpellier (1) · University Hospital, Rouen (1)
France (4) · United States (4) · Sweden (2) · Belgium (1) · Brazil (1) · Finland (1) · Germany (1) · Iran (1) · Netherlands (1) · Switzerland (1)
Jennifer Lawton, MD (2) · Alain Manrique, MD (1) · Arthur A Wilde, MD PhD (1) · Christoph Stettler, MD (1) · Frans C Visser, MD PhD (1) · Gabriel J Rinkel, MD PhD (1) · Gabriella Arlotta, MD (1) · Jan Scheitz, PD Dr. med. (1) · Karim Bendjelid, Prof. (1)
PMID 1159098, PMID 1451239, PMID 14644922, PMID 16002940, PMID 16281932, PMID 17462274, PMID 18004543, PMID 18462344, PMID 19054695, PMID 1991384, PMID 23253265, PMID 23287876, PMID 25714519, PMID 26047772, PMID 26113470, PMID 26254013, PMID 38172601, PMID 38410952, PMID 40111441, PMID 40794519, PMID 42044717, PMID 6754130, PMID 7988209, PMID 8905426, PMID 9315800