3 completed, 3 recruiting, 1 terminated, 1 withdrawn. 8 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 3, Recruiting 3, Terminated 1, Withdrawn 1 |
| Phase 1 | 3 | Recruiting 3 |
Follow Multiple Sclerosis (MS): new trials by email Literature Review of Multiple Sclerosis (MS) trials Research Report on Multiple Sclerosis (MS)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy Clemastine Fumarate, Placebo - Multiple Sclerosis (MS), Multiple Sclerosis, Relapsing-Remitting | Phase 1 / Phase 2 | Recruiting | University of California, San Francisco | 74 | 2023-08-01 | 2026-07-02 |
| Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers 18F-OP-801 - Amyotrophic Lateral Sclerosis (ALS), Parkinson Disease (PD) | Phase 1 / Phase 2 | Recruiting | Ashvattha Therapeutics, Inc. | 65 | 2023-02-02 | 2025-05-02 |
| COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders Moderna mRNA-1273, BNT162b2, Ad26.COV2.S - Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE) | Phase 2 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 258 | 2021-08-13 | 2026-06-10 |
| A Phase I Double Blind Study of Metformin Acting on Endogenous Neural Progenitor Cells in Children and Young Adults With Multiple Sclerosis Metformin, Placebo - Multiple Sclerosis (MS) | Phase 1 / Phase 2 | Recruiting | The Hospital for Sick Children | 20 | 2020-02-24 | 2025-09-23 |
| A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Progressive Forms of Multiple Sclerosis elezanumab, placebo - Multiple Sclerosis (MS) | Phase 2 | Completed | AbbVie | 123 | 2019-02-27 | 2023-12-21 |
| A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Relapsing Forms of Multiple Sclerosis elezanumab, placebo - Multiple Sclerosis (MS) | Phase 2 | Completed | AbbVie | 208 | 2018-12-11 | 2023-12-22 |
| Clinical Efficacy of Autologous Mesenchymal Bone Marrow Stem Cells in Active & Progressive Multiple Sclerosis Mesenchymal stem cells - Multiple Sclerosis (MS) | Phase 2 | Completed | Dimitrios Karussis | 48 | 2015-01-29 | 2019-08-01 |
| Alternative Treatment Paradigm for Natalizumab Trial methylprednisolone - Multiple Sclerosis (MS) | Phase 2 | Withdrawn | University of Texas Southwestern Medical Center | 2013-07-01 | 2016-12-29 |
Multiple Sclerosis (8) · Multiple Sclerosis, Chronic Progressive (2) · Alzheimer Disease (1) · Amyotrophic Lateral Sclerosis (1) · Arthritis, Juvenile (1) · Arthritis, Rheumatoid (1) · Autoimmune Diseases (1) · COVID-19 (1) · Dermatomyositis (1) · Lupus Erythematosus, Systemic (1) · Multiple Sclerosis, Relapsing-Remitting (1) · Parkinson Disease (1) · Pemphigus (1) · Scleroderma, Systemic (1)
Autoimmune Diseases of the Nervous System (8) · Demyelinating Autoimmune Diseases, CNS (8) · Demyelinating Diseases (8) · Immune System Diseases (8) · Nervous System Diseases (8) · Autoimmune Diseases (7) · Chronic Disease (2) · Disease Attributes (2) · Neuromuscular Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Arthritis (1) · Basal Ganglia Diseases (1) · Brain Diseases (1) · Central Nervous System Diseases (1)
elezanumab (2) · 2019-nCoV Vaccine mRNA-1273 (1) · Ad26COVS1 (1) · BNT162 Vaccine (1) · BNT162b5 (1) · COVID-19 Vaccines (1) · Clemastine (1) · Metformin (1) · Methotrexate (1) · Methylprednisolone (1) · Mycophenolic Acid (1) · Sugars (1)
AbbVie (2) · Ashvattha Therapeutics, Inc. (1) · Dimitrios Karussis (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · The Hospital for Sick Children (1) · University of California, San Francisco (1) · University of Texas Southwestern Medical Center (1)
United States (6) · Canada (3) · Israel (1)
Amit Bar-Or, MD, FRCP (1) · Ari J Green, MD, MCR (1) · Dinesh Khanna, MBBS, MSc (1) · E. Ann Yeh, MA, MD, FRCPC, Dip ABPN (1) · Farshad Moradi, MD (1) · Hadas Lemberg, PhD (1) · Judith A. James, MD, PhD (1) · Meggan C. Mackay, MD, MS (1) · Natasha Mckerran Ruth, MD (1) · Olaf Stuve, MD PhD (1) · Stacy Ardoin, MD (1) · Tracey Wright, MD (1) · Virginia Pascual, MD (1)