30 completed, 24 not yet recruiting, 19 unknown, 15 recruiting. 38 Not applicable, 5 Phase 2, 2 Phase 1, 1 Early Phase 1, 1 Phase 3.
Follow Multiple Pulmonary Nodules: new trials by email Literature Review of Multiple Pulmonary Nodules trials Research Report on Multiple Pulmonary Nodules
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multiparametric Lung MRI With Diffusion-Weighted Imaging in Lung-RADS 4 Lesion Characterization Multiparametric chest MRI with diffusion-weighted imaging - Solitary Pulmonary Nodule, Multiple Pulmonary Nodules | Not yet recruiting | University of Florida | 30 | 2027-01-01 | 2026-08-19 | |
| Diagnostic Performance of an AI-Based Multi-Omics Model for Early Lung Cancer Pulmonary Nodules, Early Detection of Cancer | Not yet recruiting | Beijing Chao Yang Hospital | 1050 | 2026-10-21 | 2026-10-20 | |
| AI-Based Personalized Digital Management for High-Risk Pulmonary Nodule Follow-up Personalized Digital Outreach - Pulmonary Nodules | Not applicable | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 4000 | 2026-10-01 | 2026-09-04 |
| Video-guided Versus Conventional Right-sided Double-lumen Tube Placement for Thoracoscopic Surgery Continuous video-guided right-sided double-lumen tube, Conventional right-sided double-lumen tube - Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery | Not applicable | Not yet recruiting | Diansan Su | 566 | 2026-10-01 | 2026-09-30 |
| Radiomics for Distinguishing Benign and Malignant Lung Nodules Solitary Pulmonary Nodule, Lung Neoplasms | Not yet recruiting | Assiut University | 255 | 2026-10-01 | 2026-10-01 | |
| A Multicenter Cohort Study of AI-Based Methods for Pulmonary Nodule Diagnosis and Follow-up Pulmonary Nodules, Lung Neoplasms | Not yet recruiting | Shanghai East Hospital | 16880 | 2026-10-01 | 2026-09-11 | |
| 18G Ultrafine Cryoablation Needle for Coaxial Biopsy and Cryoablation of Pulmonary Nodules 18G Ultrafine Cryoablation Needle - Pulmonary Nodules | Not applicable | Not yet recruiting | Shanghai Chest Hospital | 30 | 2026-09-01 | 2026-09-08 |
| A Randomized Controlled Trial Comparing Percutaneous CT-Guided Biopsy and Shape-Sensing Robotic-Assisted Bronchoscopy Shape-Sensing Robotic-Assisted Bronchoscopy with Cone-Beam CT (ssRAB with CBCT), CT-guided percutaneous lung nodule biopsy - Lung Cancer (Diagnosis), Lung Nodule | Phase 4 | Recruiting | Intuitive Surgical | 550 | 2026-08-28 | 2026-09-25 |
| A Randomized Controlled Trial of 3D Airway Reconstruction for Precise Double-Lumen Bronchial Intubation 3D Airway Reconstruction-Guided Double-Lumen Tube Intubation, Gender and Height-Based Double-Lumen Tube Selection - Pulmonary Nodules | Not applicable | Recruiting | Peking Union Medical College Hospital | 174 | 2026-08-14 | 2026-09-02 |
| Single-Center CyTOF and Viral Imprinting Study in Postoperative Multiple Pulmonary Nodules Multiple Pulmonary Nodules | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 200 | 2026-07-01 | 2026-06-15 | |
| Multicenter Prospective Validation of AI Models for Malignancy Risk Prediction in Pulmonary Nodules Pulmonary Nodules | Not yet recruiting | Guangdong Provincial People's Hospital | 3000 | 2026-07-01 | 2026-07-27 | |
| Peripheral Blood CyTOF and Viral Imprinting in Postoperative Multiple Pulmonary Nodules Multiple Pulmonary Nodules | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 200 | 2026-07-01 | 2026-06-15 | |
| Intraoperative Longitude-Latitude-Depth Localization Versus Preoperative CT-Guided Percutaneous Lung Puncture Localization for 0.8-2 cm Peripheral Pulmonary Nodules Longitude-Latitude-Depth Localization, CT-Guided Percutaneous Lung Puncture Localization - Pulmonary Nodule, Solitary, Peripheral Pulmonary Nodules | Not applicable | Recruiting | Qilu Hospital of Shandong University | 274 | 2026-07-01 | 2026-10-01 |
| Deep Learning Time-Series Prediction of Long-Term Growth Patterns of Pulmonary Ground-Glass Nodules Using Serial CT Serial Thin-Slice Chest CT - Pulmonary Nodules, Lung Neoplasms | Not yet recruiting | Peking University People's Hospital | 4750 | 2026-06-01 | 2026-06-15 | |
| Application of Electromagnetic Navigation System in Pulmonary Nodule Localization Electromagnetic Navigation-Guided Percutaneous Localization of Pulmonary Nodules, CT-Guided Percutaneous Localization of Pulmonary Nodules - Pulmonary Nodules, Early-Stage Lung Cancer | Not applicable | Not yet recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 400 | 2026-05-01 | 2026-05-19 |
| Robotic-Assisted Bronchoscopy-Guided Synchronous Biopsy and Radiofrequency Ablation for Pulmonary Nodules Robotic-assisted bronchoscopy-guided synchronous biopsy and radiofrequency ablation for pulmonary nodules - Pulmonary Nodules | Not applicable | Not yet recruiting | Shanghai Chest Hospital | 76 | 2026-05-01 | 2026-04-28 |
| Cadherin 3(CDH3)-Targeted PET in Lung Malignant Tumors PET/CT scans - Non-Small Cell Lung Cancer, Malignant Neoplasm | Recruiting | Peking University People's Hospital | 80 | 2026-03-18 | 2026-04-02 | |
| Non-intubated Versus Intubated Anesthesia for Thoracoscopic Sublobar Resection Non-intubated Anesthesia, Conventional Intubated General Anesthesia, Laryngeal Mask Airway (LMA) - Pulmonary Nodules, Lung Neoplasms | Not applicable | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 1600 | 2026-03-01 | 2026-02-09 |
| Hybrid Robot-Assisted Percutaneous Ablation and Non-Intubated VATS for Multiple Pulmonary Nodules Hybrid Robot-Assisted Percutaneous Intervention and Non-Intubated Video-Assisted Thoracoscopic Surgery - Multiple Pulmonary Nodules | Not applicable | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 30 | 2026-02-28 | 2026-02-09 |
| Tubeless Strategy for Enhanced Recovery After Sublobar Resection Laryngeal Mask Airway, Thoracic Paravertebral Block with Local Anesthetic, Non-intubated Anesthesia - Pulmonary Nodules, Early Stage Lung Cancer (I and II) | Not applicable | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 138 | 2026-02-01 | 2026-02-13 |
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PMID 28240562, PMID 31725158, PMID 33785209, PMID 35430086, PMID 12761311, PMID 15364752, PMID 16530369, PMID 19808195, PMID 21512092, PMID 21810706, PMID 21869676, PMID 22980667, PMID 23239643, PMID 23385998, PMID 23595643, PMID 23649436, PMID 25282285, PMID 25417130, PMID 26135833, PMID 26214244, PMID 26367186, PMID 26479161, PMID 27108299, PMID 28884222, PMID 29447239, PMID 29877715, PMID 30304509, PMID 30672172, PMID 31285876, PMID 31339018, PMID 31860329, PMID 32450240, PMID 33209621, PMID 33538338, PMID 33547938, PMID 34370981, PMID 35313102, PMID 35399240, PMID 35738412, PMID 36003715, PMID 36087843, PMID 36204866, PMID 36399997, PMID 36640994, PMID 37823052, PMID 37868257, PMID 38176863, PMID 38447771, PMID 38878052, PMID 39036382
N01CN00034 (1), P30CA016672 (1), R21CA216780 (1)