5 completed, 3 terminated, 1 recruiting, 1 withdrawn. 7 Phase 2, 2 Early Phase 1, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 5, Recruiting 1, Terminated 1 |
| Early Phase 1 | 2 | Terminated 1, Withdrawn 1 |
| Phase 1 | 2 | Recruiting 1, Terminated 1 |
Follow 4-(3-fluoropropyl)glutamic acid: new trials by email Literature Review of 4-(3-fluoropropyl)glutamic acid trials Research Report on 4-(3-fluoropropyl)glutamic acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer Biospecimen Collection, Carboplatin, Computed Tomography - Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8 | Phase 1 / Phase 2 | Recruiting | Vanderbilt-Ingram Cancer Center | 25 | 2023-05-09 | 2024-10-17 |
| A Pilot Study of Glutamine PET Imaging of Head and Neck Squamous Cell Carcinoma 18F-FSPG, 11C-Glutamine - Head and Neck Squamous Cell Carcinoma, Head and Neck Cancer | Early Phase 1 | Terminated | M.D. Anderson Cancer Center | 3 | 2022-09-14 | 2025-04-09 |
| Diagnostic Validity of [18F]FSPG PET for the Assessment of Acute Rejection After Heart or Liver Transplantation [18F]FSPG - Graft Rejection, Heart Transplantation | Phase 2 | Completed | Asan Medical Center | 7 | 2020-11-18 | 2023-07-20 |
| 18F-FSPG PET/CT in Diagnosing Early Lung Cancer in Patients With Lung Nodules Computed Tomography, Fludeoxyglucose F-18, Fluorine F 18 L-glutamate Derivative BAY94-9392 - Cigarette Smoker, Current Smoker | Phase 2 | Completed | Andrei Iagaru | 15 | 2019-02-04 | 2025-04-09 |
| Diagnostic Validity of [18F]FSPG PET for the Assessment of Disease Activity in Inflammatory Bowel Disease [18F]FSPG - Inflammatory Bowel Diseases, Ulcerative Colitis | Phase 2 | Completed | Asan Foundation | 20 | 2018-08-14 | 2020-12-14 |
| PET Imaging of Ovarian Carcinoma With 18F-FSPG (S)-4-(3-[18F]Fluoropropyl)-L-glutamic acid (18F-FSPG), Positron Emission Tomography, Laboratory Biomarker Analysis - Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Cancer | Early Phase 1 | Withdrawn | Vanderbilt-Ingram Cancer Center | 2018-06-01 | 2018-06-06 | |
| 18F-FSPG PET/MRI or PET/CT Imaging of Cardiac Sarcoidosis or Inflammation 18F-FSPG - Cardiac Sarcoidosis, Myocardial Inflammation | Phase 2 | Terminated | Stanford University | 45 | 2017-08-02 | 2023-04-07 |
| 18F-FSPG PET/CT for Cancer Patients on Therapy 18F-FSPG, 18F-FDG - B-Cell Neoplasm, Estrogen Receptor Negative | Phase 2 | Completed | Andrei Iagaru | 7 | 2015-07-01 | 2019-01-03 |
| 18F-FSPG PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules Computed Tomography, fluorodeoxyglucose F-18, Fluorine F 18 L-glutamate Derivative BAY94-9392 - Lung Carcinoma, Solitary Pulmonary Nodule | Phase 2 | Completed | Vanderbilt-Ingram Cancer Center | 46 | 2015-06-16 | 2022-10-19 |
| PET Imaging of Intracranial Cancers With 18F-FSPG 18F-FSPG - Brain Cancer | Phase 1 | Terminated | Lantheus Biosciences Ltd. | 26 | 2014-11-01 | 2016-09-02 |
Carcinoma, Non-Small-Cell Lung (2) · Lung Neoplasms (2) · Brain Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Renal Cell (1) · Cigarette Smoking (1) · Colitis, Ulcerative (1) · Crohn Disease (1) · Fallopian Tube Neoplasms (1) · Head and Neck Neoplasms (1) · Inflammatory Bowel Diseases (1) · Lymphoma, B-Cell (1) · Mesothelioma (1) · Multiple Pulmonary Nodules (1) · Myocarditis (1)
Vanderbilt-Ingram Cancer Center (3) · Andrei Iagaru (2) · Asan Foundation (1) · Asan Medical Center (1) · Lantheus Biosciences Ltd. (1) · M.D. Anderson Cancer Center (1) · Stanford University (1)
United States (7) · South Korea (2)
Andrei Iagaru, MD (1) · Andrei M Iagaru, MD (1) · Carina Mari Aparici (1) · Chirayu Shah, MD (1) · Dae Hyuk Moon, MD (1) · Evan Osmundson, MD, PhD (1) · Lesley Flynt, MD (1) · Marta Crispens, MD (1) · Norman Koglin, PhD (1)
P30CA068485 (2), P30CA124435 (1)