43 completed, 11 not yet recruiting, 11 recruiting, 11 unknown. 64 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 4.
Follow Multimorbidity: new trials by email Literature Review of Multimorbidity trials Research Report on Multimorbidity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Physical Activity Modifies Exercise Responsiveness SLIMM - Sit less, interact, move more, PB125 - Multimorbidity | Not applicable | Not yet recruiting | VA Office of Research and Development | 120 | 2027-01-01 | 2026-08-28 |
| Acceptance-based Self-care Intervention for Older Adults With Multimorbidity Acceptance-based activities, Self-care activities - Older Adults (60 - 85 Years Old), Self-care | Not applicable | Not yet recruiting | Chinese University of Hong Kong | 306 | 2027-01-01 | 2026-10-22 |
| The LifeMeds Cohort Multimorbidity, Cancer | Not yet recruiting | Tilburg University | 2000 | 2026-12-01 | 2026-09-29 | |
| CEEEC-II: A 12-Week Physical and Cognitive Enrichment Extension Study in Older Stroke Survivors With Multimorbidity Physical Enrichment, Cognitive Enrichment - Stroke, Hypertension | Not applicable | Not yet recruiting | Duke Kunshan University | 365 | 2026-08-31 | 2026-08-21 |
| Living With Multimorbidity: Care Coordination and Symptom Management Program (COORDINATE) COORDINATE Program, Enhanced Usual Care - Multimorbidity | Not applicable | Enrolling by invitation | Johns Hopkins University | 10 | 2026-07-27 | 2026-07-29 |
| Preoperative Multimorbidity and Functional Recovery After Total Knee Arthroplasty Knee Osteoarthritis, Multimorbidity | Recruiting | Balikesir Ataturk City Hospital | 230 | 2026-06-26 | 2026-10-20 | |
| Navigation for Elderly People With Multiple Morbidity After Hospital Discharge. Navigation for elderly people after hospital discharge., Routine care. - Multimorbidity | Not applicable | Not yet recruiting | Hospital de Clinicas de Porto Alegre | 148 | 2026-06-01 | 2026-04-22 |
| Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity Fisetin, Placebo - Multimorbidity, Healthy | Phase 1 / Phase 2 | Recruiting | Ove Andersen | 60 | 2026-03-24 | 2026-05-19 |
| Older Kidney Patient Optimisation Pretransplant Kidney transplant-specific comprehensive geriatric assessment - Kidney Disease, Kidney Failure | Not applicable | Not yet recruiting | Guy's and St Thomas' NHS Foundation Trust | 50 | 2026-02-02 | 2026-02-19 |
| Factors of Potentially Dangerous Drug Interactions in Patients With Cardiovascular Diseases and Multimorbidity Cardiovascular Diseases, Multimorbidity | Active not recruiting | National Medical Research Center for Therapy and Preventive Medicine | 120 | 2026-01-25 | 2026-06-16 | |
| Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 2 Annual Wellness Visit, Annual Wellness Visits + Geriatric Resources and Assessment for the Care of Elders (AWV + GRACE) - Aging, Preventive Care | Not applicable | Recruiting | Massachusetts General Hospital | 7140 | 2026-01-06 | 2026-10-06 |
| Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity Service Package Group - Multimorbidity, Hypertension | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 358 | 2025-12-01 | 2025-09-03 |
| A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students The intervention group participated in specialized physical education courses. - Multimorbidity, Comorbidity | Not applicable | Not yet recruiting | Xiaoyan Wu | 200 | 2025-11-15 | 2025-11-20 |
| Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization. - Prescribing Decisions, Diabetes | Not applicable | Active not recruiting | University of Pittsburgh | 64 | 2025-11-13 | 2026-09-02 |
| Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT integrated care intervention tailored to the needs of older adults leaving at home with mood disorders and multimorbidity in Leuven - Multimorbidity, Older Adults (65 Years and Older) | Not applicable | Recruiting | KU Leuven | 82 | 2025-10-01 | 2025-12-12 |
| Health Chat for Empowerment-based Lifestyle Planning for Cardiometabolic Multimorbidity HcELP_CMM, Usual Care - Cardiometabolic Diseases, Multimorbidity | Not applicable | Recruiting | The University of Hong Kong | 232 | 2025-09-08 | 2026-05-11 |
| Multimorbidity and Cardiovascular Risk Factors After Renal Transplant Kidney Transplant, Cardiovascular (CV) Risk | Recruiting | University Hospitals of Derby and Burton NHS Foundation Trust | 30 | 2025-09-05 | 2025-10-03 | |
| The Impact of Nurse Practitioner-Led Multidisciplinary Team Intervention on the Implementation of Guideline-Directed Medical Therapy and Clinical Outcomes in Adults With Multimorbidity NP-led MDT, Usual Care - Multimorbidity | Not applicable | Active not recruiting | National Taiwan University Hospital | 178 | 2025-09-02 | 2026-03-19 |
| TimelyCare - A Proactive Primary Care Model: Delivering the Right Care at the Right Time for Individuals at Risk of High Care Consumption Timely Care, - Multimorbidity, Integrated Care | Not applicable | Enrolling by invitation | Linnaeus University | 1200 | 2025-09-01 | 2026-10-27 |
| Community-Empowerment and Environmental Enrichment-based Co-management (CEEEC) Model and Mechanisms for Improving Health of Older Stroke Patients With Multimorbidity Exercise Intervention, Cognitive Intervention - Hypertension, Type 2 Diabetes Mellitus (T2DM) | Not applicable | Active not recruiting | Duke Kunshan University | 600 | 2025-06-20 | 2026-10-21 |
Showing 20 of 90. Sign in to see all of them.
Motor Activity (8) · Hypertension (7) · Cardiovascular Diseases (5) · Diabetes Mellitus (5) · Chronic Disease (4) · Cognitive Dysfunction (4) · Depression (4) · Frailty (4) · Medication Adherence (4) · Stroke (4) · Diabetes Mellitus, Type 2 (3) · Dyslipidemias (3) · Multiple Chronic Conditions (3) · Neoplasms (3) · Renal Insufficiency, Chronic (3)
Behavior (21) · Pathological Conditions, Signs and Symptoms (18) · Pathologic Processes (16) · Disease Attributes (13) · Nutritional and Metabolic Diseases (13) · Endocrine System Diseases (9) · Metabolic Diseases (9) · Cardiovascular Diseases (8) · Chronic Disease (8) · Glucose Metabolism Disorders (8) · Health Behavior (8) · Mental Disorders (8) · Vascular Diseases (8) · Treatment Adherence and Compliance (7) · Neurocognitive Disorders (6)
Multimorbidity (5) · Exercise (3) · Surveys and Questionnaires (3) · Educational Status (2) · Aging (1) · Ambulatory Care Facilities (1) · Control Groups (1) · Drug Interactions (1) · Focus Groups (1) · Health (1) · Lysine Acetyltransferase 5 (1) · Medication Review (1) · Methods (1) · Nutrition Assessment (1) · Palliative Care (1)
VA Office of Research and Development (7) · Peking Union Medical College (4) · Massachusetts General Hospital (3) · Central Jutland Regional Hospital (2) · Duke Kunshan University (2) · Instituto Aragones de Ciencias de la Salud (2) · Johns Hopkins University (2) · National Medical Research Center for Therapy and Preventive Medicine (2) · University Hospital, Brest (2) · University of Cadiz (2) · A.O.U. Città della Salute e della Scienza (1) · Assistance Publique - Hôpitaux de Paris (1) · Azienda Ospedaliero-Universitaria di Parma (1) · Balikesir Ataturk City Hospital (1) · Chinese University of Hong Kong (1)
United States (15) · China (8) · Denmark (7) · Spain (6) · France (4) · Sweden (4) · Switzerland (4) · Canada (3) · Finland (3) · Germany (3) · Portugal (3) · United Kingdom (3) · Belgium (2) · Brazil (2) · Ireland (2)
Simiao Chen, Ph.D. (4) · Daniel Prados-Torres, MD, PhD (2) · Jennifer E. Stevens-Lapsley, PhD (2) · Susan N. Hastings, MD (2) · Alexandra Prados-Torres, MD, PhD (1) · Alexandra Prados-Torres, MD,PhD (1) · Anne Tournadre (1) · Antonia J Cronin, MBBS MA PhD (1) · Benissa E. Salem, PhD, MSN, RN, CNL, PHN (1) · Bernardo Neves, MD (1) · Binu Koirala, PhD (1) · Binu Koirala, PhD, MGS (1)
PMID 11438408, PMID 11866651, PMID 12646602, PMID 12835199, PMID 15381343, PMID 18026804, PMID 18387184, PMID 18504506, PMID 19543809, PMID 20171455, PMID 21383355, PMID 21735403, PMID 22184686, PMID 22790107, PMID 23064272, PMID 24721435, PMID 25437404, PMID 26187183, PMID 27384919, PMID 27483975, PMID 28239781, PMID 28487349, PMID 28710713, PMID 29088989, PMID 29196982, PMID 29273595, PMID 29654038, PMID 29743156, PMID 30191144, PMID 31481568, PMID 31489559, PMID 31742234, PMID 32071189, PMID 32087011, PMID 32149715, PMID 32525811, PMID 32554653, PMID 32579616, PMID 32841366, PMID 32853429, PMID 32946885, PMID 33023497, PMID 33117558, PMID 33793285, PMID 33909607, PMID 34157981, PMID 34495726, PMID 35485287, PMID 35562684, PMID 35629175
2016 (1), 2023 (1), K76AG074878 (1), P30NR018093 (1), R01LM012815 (1)