6 recruiting, 5 completed, 1 active not recruiting, 1 not yet recruiting. 5 Not applicable, 1 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Not yet recruiting 1, Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Migraine Disease: new trials by email Literature Review of Migraine Disease trials Research Report on Migraine Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Migraine Headaches Elimination With Patent Foramen Ovale-Directed Therapy Prasugrel 5mg, Transcatheter Closure of Patent Foramen Ovale - Migraine Disease, Patent Foramen Ovale | Phase 3 | Recruiting | Columbia University | 32 | 2026-10-15 | 2026-10-08 |
| A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department Rimegepant, Zavegepant - Migraine, Migraine Disease | Phase 1 | Recruiting | University of South Florida | 100 | 2026-09-15 | 2026-10-27 |
| Evaluation of the Migraceutics® Phase-Specific Dietary Supplement Regimen on Quality of Life, Work Productivity, and Biomarkers in Adult Migraineurs: The Migraceutics® START Study Foundational dietary supplement, Luteal phase dietary supplement add-on, Migraine phase dietary supplement add-on - Migraine, Migraine Disease | Not applicable | Not yet recruiting | Miracle Wellness LLC | 920 | 2026-07-08 | 2026-06-08 |
| Aerobic Exercise and Its Impact on Sensory, Musculoskeletal, and Psychosocial Aspects in Migraine Supervised Aerobic Exercise plus Pain Neuroscience Education, Physical Activity Recommendations - Migraine, Migraine Disease | Not applicable | Recruiting | University of Sao Paulo | 100 | 2026-03-03 | 2026-04-28 |
| Neuropsychological Profile Characterization in Patients With Migraine: Cognitive Functioning and Psychological Variables Migraine, Migraine Disease | Recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 150 | 2025-09-01 | 2026-02-11 | |
| Effects of Foot Reflexology Massage in Migraine Reflexology Massage - Migraine Disease | Not applicable | Completed | Karabuk University | 22 | 2025-06-01 | 2026-04-15 |
| Effects of Progressive Muscle Relaxation Training Applied in Addition to Aerobic Exercise Training in Individuals With Migraine Diagnosis aerobic exercise and relaxation trainig, aerobic exercise - Migraine, Migraine Disease | Not applicable | Completed | Mardin Artuklu University | 44 | 2025-05-25 | 2026-05-15 |
| Childhood Migraine Treatment Noninvasive Pulsed Radiofrequency vs Flunarizine Radiofrequency, flunarizine - Migraine Disease | Active not recruiting | Damla Yürük | 60 | 2024-10-01 | 2025-01-13 | |
| Long-term Atogepant in Real-world Practice Atogepant 60 mg, Headache diary, Patient-reported outcome measures - Migraine, Headache | Completed | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | 513 | 2024-06-01 | 2026-09-23 | |
| High-Density EEG-MEG-wearable EEG: Comparison of Quantitative Electroencephalographic Indicators as Neurophysiological Markers of Effectiveness of Mindfulness Therapy in Addition to Standard Treatment in Patients With High-frequency Episodic Migraine Mindfulness treatment - Migraine, Migraine Disease | Recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 40 | 2024-04-23 | 2026-09-01 | |
| Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals Caffeine (200 mg), triptans, NSAID (Nonsteroidal anti-inflammatory drugs) - Migraine, Migraine Disease | Phase 4 | Recruiting | Ain Shams University | 120 | 2023-04-26 | 2025-06-15 |
| Diaphragm Relaxation Techniques, Diaphragmatic Breathing Exercises for Migraine Patients Manual therapy, Diaphragmatic relaxation technique, Shoulder ROM exercise - Migraine, Migraine Disease | Not applicable | Completed | Seda Saka | 42 | 2023-01-01 | 2025-08-28 |
| The Migraine and Pain Study GeneBank at Scripps Clinic Registry (MAPS) Migraine Disease | Completed | Scripps Translational Science Institute | 61 | 2009-01-01 | 2015-10-16 |
Migraine Disorders (12) · Headache (4) · Agnosia (1) · Cognitive Dysfunction (1) · Foramen Ovale, Patent (1) · Headache Disorders (1) · Headache Disorders, Primary (1) · Migraine with Aura (1) · Migraine without Aura (1) · Motor Activity (1) · Neck Pain (1) · Prescription Drug Overuse (1) · Sensation Disorders (1)
Brain Diseases (12) · Central Nervous System Diseases (12) · Nervous System Diseases (12) · Headache Disorders (11) · Headache Disorders, Primary (11) · Neurologic Manifestations (4) · Pain (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Mental Disorders (2) · Behavior (1) · Cardiovascular Abnormalities (1) · Cardiovascular Diseases (1) · Chemically-Induced Disorders (1) · Cognition Disorders (1)
Musculoskeletal Manipulations (2) · Acetaminophen (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Caffeine (1) · Exercise (1) · Flunarizine (1) · Patient Reported Outcome Measures (1) · Prasugrel Hydrochloride (1) · Tryptamines (1) · atogepant (1) · rimegepant sulfate (1)
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (2) · Ain Shams University (1) · Columbia University (1) · Damla Yürük (1) · Fundación de Investigación Biomédica - Hospital Universitario de La Princesa (1) · Karabuk University (1) · Mardin Artuklu University (1) · Miracle Wellness LLC (1) · Scripps Translational Science Institute (1) · Seda Saka (1) · University of Sao Paulo (1) · University of South Florida (1)
Turkey (Türkiye) (4) · United States (4) · Italy (2) · Brazil (1) · Egypt (1) · Spain (1)
Ana Beatriz Gago Veiga (1) · Christy M Jackson, M.D. (1) · Danilo A Montisano, MD (1) · Jessica Ailani, MD (1) · Paola Lanteri, MD (1) · Robert J Sommer, MD (1)