300 completed, 85 terminated, 79 unknown, 75 recruiting. 245 Phase 2, 225 Phase 1, 78 Not applicable, 57 Phase 3, 8 Early Phase 1.
Follow Metastatic Cancer: new trials by email Literature Review of Metastatic Cancer trials Research Report on Metastatic Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapy 177Lu-PSMA-I&T - escalating renal absorbed dose, 177Lu-PSMA-I&T - recommended phase 2 regime - Cancer, Prostate Cancer | Phase 1 / Phase 2 | Not yet recruiting | CHU de Quebec-Universite Laval | 500 | 2028-03-01 | 2025-03-30 |
| Real-world Trial of Individualized Precision Oncology Molecularly matched therapy, Standard of care - Metastatic Cancer, Unresectable Carcinoma | Phase 2 | Not yet recruiting | University of California, San Diego | 280 | 2026-12-01 | 2026-09-03 |
| Y-NM600 in Patients Receiving Anti-PD-1 or Anti-PD-L1 for Metastatic Cancer 90Y-NM600 - Metastatic Cancer | Phase 1 | Recruiting | University of Wisconsin, Madison | 60 | 2026-11-01 | 2026-08-19 |
| IL-15 Enhanced NK Cell Therapy for Solid Tumors IL-15 enhanced engineered NK cells, IL-15 Enhanced Engineered NK Cells - Solid Tumors, Metastatic Cancer | Early Phase 1 | Recruiting | Genovn Therapeutics (Suzhou) Co., Ltd. | 12 | 2026-10-08 | 2026-09-30 |
| Evaluating Interventional Radiology for Cancer Pain Management Self-reported questionnaires - Locally Advanced Cancer, Metastatic Cancer | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 125 | 2026-09-01 | 2026-04-14 |
| Trial Comparing LATTICE Radiotherapy vs Moderately Dose-escalated Palliative Radiation for Patients With Metastases. LATTICE Radiotherapy, Standard radiotherapy - Metastases, Metastatic Cancer | Phase 2 | Recruiting | Stanford University | 80 | 2026-08-28 | 2026-09-09 |
| Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases Zanzalintinib, Investigator Choice of Bone Strengthening Agents (BSA), Non-Investigational Radiation Therapy (RT) - Clear Cell Renal Cell Cancer (ccRCC), Clear Cell Renal Carcinoma | Phase 2 | Recruiting | Kelly Fitzgerald, MD | 20 | 2026-06-10 | 2026-07-27 |
| Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy [68Ga]Ga-ABY-025 - Locally Advanced Cancer, Metastatic Cancer | Early Phase 1 | Recruiting | Vanderbilt-Ingram Cancer Center | 30 | 2026-04-16 | 2026-05-08 |
| Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2) Givastomig, Nivolumab, 5Fluorouracil - Solid Tumor, Advanced Cancer | Phase 2 | Recruiting | I-Mab Biopharma US Limited | 180 | 2026-02-11 | 2026-05-14 |
| A Study to Assess the Ability of Stereotactic Radiotherapy to Restore the Efficacy of Immunotherapy in Patients With Metastatic Cancer. Stereotactic Radiotherapy - Metastatic Cancer | Not applicable | Recruiting | Elsan | 35 | 2026-01-27 | 2026-04-23 |
| Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas Balstilimab, Botensilimab, Folfox Protocol - Gastric Cancer, MSI-H | Phase 3 | Recruiting | Centre Leon Berard | 132 | 2025-12-08 | 2026-06-25 |
| STM-06: POLARIS-POlymetastic Lesion Ablative Radiotherapy With Immunotherapy Study Ablative radiation treatment - Advanced Solid Tumor, Metastatic Cancer | Phase 1 | Recruiting | University of Illinois at Chicago | 28 | 2025-12-08 | 2026-03-02 |
| Application of ⁶⁸Ga-FXX489 (NNS309) PET/CT Imaging in Diagnosis of Tumor Diseases. 68Ga-FXX489, Positron Emission Tomography (PET) imaging, Gallium-68 labelled (68Ga-) FAP-2286 - Tumor, Metastatic Cancer | Phase 1 | Recruiting | Yi Tian | 30 | 2025-09-11 | 2026-04-03 |
| CSB-321 Ph 1 in Immunotherapy for the Treatment of Cancer [18F]CSB-321 - Metastatic Cancer, Unresectable Solid Tumor | Phase 1 | Not yet recruiting | Cytosite Biopharma Inc. | 40 | 2025-09-01 | 2025-07-09 |
| Longitudinal Screening for Financial Hardship to Improve Outcomes in Patients With Advanced Cancer Financial Hardship Screening, Enhanced Usual Care - Advanced Cancer, Metastatic Cancer | Not applicable | Recruiting | Alliance Foundation Trials, LLC. | 1000 | 2025-07-01 | 2026-05-12 |
| PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival Expert Review, Blood or tissue samples collection., The Precision Oncology Navigation - Solid Tumor Malignancies, Metastatic Cancer | Not applicable | Recruiting | UNC Lineberger Comprehensive Cancer Center | 500 | 2025-06-27 | 2026-07-14 |
| Transarterial Chemoembolization (TACE) Plus Bevacizumab for Liver Metastases Bevacizumab - Cancer, Metastatic Cancer | Phase 1 / Phase 2 | Active not recruiting | Pardis Noor Medical Imaging and Cancer Center | 40 | 2025-06-01 | 2026-09-16 |
| COBRA: Cancer, Older Adults, Balance and Resistance Activities Cancer, Older adults, Balance and Resistance Activities - Primary Cancer, Metastatic Cancer | Not applicable | Active not recruiting | Memorial Sloan Kettering Cancer Center | 38 | 2025-05-30 | 2026-04-24 |
| SLV-154 Treatment of Advanced Cancers SLV-154 - Advanced Cancer, Advanced Solid Tumor | Phase 1 | Recruiting | Solve Therapeutics | 250 | 2025-05-14 | 2026-09-22 |
| Study of Interactions Between Oncologists and Resuscitators to Optimize Decision Making for Admission of Patients With Metastatic Solid Cancer to the ICU (InterOncoRea) Descriptive analysis - Intensive Care Unit (ICU) Patients, Metastatic Cancer | Active not recruiting | University Hospital, Brest | 139 | 2025-03-01 | 2025-05-29 |
Showing 20 of 621. Sign in to see all of them.
Neoplasm Metastasis (621) · Neoplasms (92) · Colorectal Neoplasms (90) · Brain Neoplasms (76) · Carcinoma, Non-Small-Cell Lung (71) · Colonic Neoplasms (69) · Breast Neoplasms (64) · Lung Neoplasms (59) · Melanoma (55) · Rectal Neoplasms (53) · Prostatic Neoplasms (42) · Ovarian Neoplasms (35) · Pancreatic Neoplasms (33) · Carcinoma, Renal Cell (29) · Carcinoma, Hepatocellular (27)
Pathological Conditions, Signs and Symptoms (621) · Neoplastic Processes (620) · Pathologic Processes (620) · Neoplasms (529) · Neoplasms by Site (397) · Neoplasms by Histologic Type (186) · Digestive System Diseases (162) · Digestive System Neoplasms (161) · Neoplasms, Glandular and Epithelial (137) · Gastrointestinal Diseases (128) · Gastrointestinal Neoplasms (122) · Urogenital Diseases (114) · Urogenital Neoplasms (111) · Skin Diseases (110) · Skin and Connective Tissue Diseases (110)
Fluorouracil (32) · pembrolizumab (32) · Leucovorin (30) · Radiotherapy (29) · Radiosurgery (25) · Oxaliplatin (23) · Irinotecan (20) · Nivolumab (20) · Bevacizumab (19) · Cyclophosphamide (17) · Capecitabine (15) · Radiofrequency Ablation (15) · aldesleukin (14) · Cetuximab (13) · Zoledronic Acid (13)
Memorial Sloan Kettering Cancer Center (20) · Alliance for Clinical Trials in Oncology (18) · National Cancer Institute (NCI) (18) · M.D. Anderson Cancer Center (13) · European Organisation for Research and Treatment of Cancer - EORTC (11) · Duke University (10) · Case Comprehensive Cancer Center (9) · Eli Lilly and Company (9) · Radiation Therapy Oncology Group (9) · Amgen (8) · Northwestern University (8) · SWOG Cancer Research Network (8) · City of Hope Medical Center (7) · National Institutes of Health Clinical Center (CC) (7) · Centre Leon Berard (6)
United States (383) · France (72) · Canada (46) · United Kingdom (43) · China (33) · Italy (30) · Spain (30) · Belgium (29) · Germany (24) · Australia (23) · Netherlands (21) · South Korea (21) · Switzerland (15) · Taiwan (13) · Japan (12)
Steven A Rosenberg, M.D. (8) · Nancy E. Kemeny, MD (5) · Darell D. Bigner, MD, PhD (4) · H. Richard Alexander, MD, FACS (4) · Svetomir Markovic, MD, PhD (4) · David M. Peereboom, MD (3) · David S. Schrump, MD (3) · Jana Portnow, MD (3) · Judith M. Ford, MD, PhD (3) · Lillian Siu, MD, FRCPC (3) · Paul D. Brown, MD (3) · Steven A. Curley, MD (3)
PMID 36897458, PMID 33270906, PMID 38421252, PMID 11913730, PMID 12082455, PMID 12082456, PMID 12356141, PMID 12622453, PMID 12782596, PMID 14572748, PMID 14673042, PMID 15050309, PMID 15158627, PMID 15764775, PMID 15928300, PMID 16009951, PMID 16009952, PMID 16062084, PMID 16230673, PMID 16314619, PMID 16314647, PMID 16505413, PMID 16533779, PMID 16814950, PMID 17401015, PMID 17418968, PMID 17985341, PMID 17987262, PMID 18008108, PMID 18349311, PMID 18358928, PMID 18406884, PMID 18520231, PMID 18588404, PMID 18988231, PMID 19060590, PMID 19200368, PMID 19233901, PMID 19372041, PMID 19554377, PMID 19602035, PMID 19632065, PMID 19706802, PMID 19726226, PMID 19735988, PMID 20041484, PMID 20042969, PMID 20234364, PMID 20533023, PMID 20576718
P30CA043703 (8), 2023 (6), P30CA033572 (6), 2016 (5), P30CA016672 (5), P30CA022453 (5), U10CA031946 (5), U10CA032102 (5), 2015 (4), P30CA060553 (3), 2019 (2), P30CA008748 (2), P30CA015083 (2), P30CA068485 (2), P30CA072720 (2)