2 completed, 2 recruiting, 2 terminated, 1 active not recruiting. 8 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 8 | Completed 2, Recruiting 2, Terminated 2, Active not recruiting 1, Withdrawn 1 |
Follow Metastatic Cancer: new trials by email Literature Review of Metastatic Cancer trials Research Report on Metastatic Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IL-15 Enhanced NK Cell Therapy for Solid Tumors IL-15 enhanced engineered NK cells, IL-15 Enhanced Engineered NK Cells - Solid Tumors, Metastatic Cancer | Early Phase 1 | Recruiting | Genovn Therapeutics (Suzhou) Co., Ltd. | 12 | 2026-10-08 | 2026-09-30 |
| Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy [68Ga]Ga-ABY-025 - Locally Advanced Cancer, Metastatic Cancer | Early Phase 1 | Recruiting | Vanderbilt-Ingram Cancer Center | 30 | 2026-04-16 | 2026-05-08 |
| Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer 18F-Clofarabine - Metastatic Cancer, Carcinoma | Early Phase 1 | Terminated | Roberto Vargas | 5 | 2023-03-06 | 2026-08-07 |
| A Novel Method for Treating Lung Met w/Combo of Electric Fields & Rad Therapy: A Single-Arm Irreversible electroporation (IRE) ablation, Radiation Therapy - Lung Tumor, Metastatic Cancer | Early Phase 1 | Completed | University of California, Irvine | 6 | 2023-01-03 | 2025-05-14 |
| Cholesterol Disruption in Combination With the Standard of Care in Patients With Advanced Pancreatic Adenocarcinoma Cholesterol metabolism disruption - Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer | Early Phase 1 | Active not recruiting | CHU de Quebec-Universite Laval | 3 | 2021-10-04 | 2026-03-19 |
| Personalized Vaccine Generated by Autologous Dendritic Cells Pulsed With Autologous Whole Tumor Cell Lysate Treat Advanced Solid Tumor Patients With High Tumor Mutation Burden personalized DC vaccine - Advanced Cancer, Metastatic Cancer | Early Phase 1 | Withdrawn | Capital Medical University | 2018-09-11 | 2024-02-07 | |
| Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases Pemetrexed - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Early Phase 1 | Completed | Northwestern University | 15 | 2007-01-01 | 2021-09-08 |
| 11C Topotecan PET Imaging computed tomography, positron emission tomography, 11C topotecan - Lung Cancer, Metastatic Cancer | Early Phase 1 | Terminated | Case Comprehensive Cancer Center | 7 | 2004-12-01 | 2012-03-20 |
Neoplasm Metastasis (8) · Neoplasms (3) · Brain Neoplasms (2) · Lung Neoplasms (2) · Adenocarcinoma (1) · Blast Crisis (1) · Breast Neoplasms (1) · Burkitt Lymphoma (1) · Carcinoma (1) · Carcinoma, Ovarian Epithelial (1) · Central Nervous System Neoplasms (1) · Congenital Abnormalities (1) · Esophageal Squamous Cell Carcinoma (1) · Hodgkin Disease (1) · Hyperlipoproteinemia Type II (1)
Neoplastic Processes (8) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Neoplasms (5) · Neoplasms by Site (5) · Neoplasms by Histologic Type (4) · Neoplasms, Glandular and Epithelial (3) · Brain Diseases (2) · Carcinoma (2) · Central Nervous System Diseases (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Digestive System Diseases (2) · Digestive System Neoplasms (2) · Endocrine Gland Neoplasms (2) · Endocrine System Diseases (2)
Atorvastatin (1) · Electroporation (1) · Ezetimibe (1) · Fluorodeoxyglucose F18 (1) · Magnetic Resonance Spectroscopy (1) · Pemetrexed (1) · Radiotherapy (1) · evolocumab (1)
CHU de Quebec-Universite Laval (1) · Capital Medical University (1) · Case Comprehensive Cancer Center (1) · Genovn Therapeutics (Suzhou) Co., Ltd. (1) · Northwestern University (1) · Roberto Vargas (1) · University of California, Irvine (1) · Vanderbilt-Ingram Cancer Center (1)
United States (5) · China (2) · Canada (1)
Anne Gangloff, MD PhD FRCPC (1) · Anne-Marie Carreau, MD FRCPC (1) · Francine Aubin, MD FRCPC (1) · Jeffrey J. Raizer, MD (1) · Jeremy Harris, MD (1) · Nabil G. Seidah, PhD (1) · Olivier Dumas, MD FRCPC (1) · Raymond Muzic, PhD (1) · Roberto Vargas, MD (1) · Vincent Castonguay, MD FRCPC (1)
P30CA043703 (1)