3 unknown, 2 recruiting, 2 terminated, 1 active not recruiting. 10 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 10 | Unknown 3, Recruiting 2, Terminated 2, Active not recruiting 1, Completed 1, Withdrawn 1 |
Follow Lung Injury: new trials by email Literature Review of Lung Injury trials Research Report on Lung Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Single Dose, Dose Escalation Clinical Trial on the Safety, Tolerability and Efficacy of Lyophilized Powder for Inhalation of Recombinant Human Keratinocyte Growth Factor-2 (Rh-KGF-2) in The Treatment of Patients With Acute Respiratory Distress Syndrome Recombinant Human Keratinocyte Growth Factor-2 for Inhalation (Lyophilized Powder) - ARDS (Moderate or Severe), ARDS (Acute Respiratory Distress Syndrome) | Early Phase 1 | Recruiting | Shanghai Zhongshan Hospital | 24 | 2026-05-14 | 2026-06-11 |
| Metformin for Premature Infants With Bronchopulmonary Dysplasia Metformin (open-label) - Bronchopulmonary Dysplasia (BPD) | Early Phase 1 | Recruiting | Medical College of Wisconsin | 40 | 2025-12-19 | 2026-01-26 |
| Using Silica 12CH to Mitigate the Effects and Symptoms of Silicosis in Brazil Silica 12CH - Silicosis | Early Phase 1 | Unknown | HOHM Foundation | 100 | 2024-03-01 | 2024-02-28 |
| FAPI PET for Lung Fibrosis 68Ga-FAPi-46, Computed Tomography, Positron Emission Tomography - Interstitial Lung Disease, Idiopathic Interstitial Pneumonias | Early Phase 1 | Active not recruiting | University of California, Los Angeles | 30 | 2021-11-16 | 2026-08-20 |
| Application of hUC-MSCs in Treating Acute Lung Injury: a Single Center Prospective Clinical Research human derived umbilical cord derived mesenchymal stem cells - Acute Lung Injury | Early Phase 1 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 30 | 2021-06-09 | 2021-07-07 |
| Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders HP 3He, HP 129Xe, PFP - Lung Transplant, Lung Resection | Early Phase 1 | Terminated | Thunder Bay Regional Health Research Institute | 10 | 2020-11-10 | 2024-10-15 |
| L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia L-Citrulline - Infant,Premature, Bronchopulmonary Dysplasia | Early Phase 1 | Terminated | University of Utah | 16 | 2019-07-30 | 2024-06-10 |
| Stem Cells for Bronchopulmonary Dysplasia transplantation of mesenchymal stem cell, no transplantation of mesenchymal stem cell - Bronchopulmonary Dysplasia | Early Phase 1 | Withdrawn | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 2017-11-01 | 2023-05-01 | |
| 68Ga-NOTA-PRGD2 PET/CT in Patients With Lung Injury and Pulmonary Fibrosis 68Ga-NOTA-PRGD2, PET/CT - Pulmonary Fibrosis, Unspecified | Early Phase 1 | Unknown | Peking Union Medical College Hospital | 30 | 2015-05-01 | 2017-04-06 |
| Exploratory Clinical Study of Neutrophil Activation Probe (NAP) for Optical Molecular Imaging in Human Lungs Microdose of NAP - Acute Lung Injury | Early Phase 1 | Completed | University of Edinburgh | 15 | 2014-10-01 | 2019-11-05 |
Acute Lung Injury (3) · Bronchopulmonary Dysplasia (3) · Pulmonary Fibrosis (3) · Hypertension, Pulmonary (2) · Lung Diseases, Interstitial (2) · Premature Birth (2) · Alveolitis, Extrinsic Allergic (1) · Asbestosis (1) · Asthma (1) · Bronchiectasis (1) · Cystic Fibrosis (1) · Emphysema (1) · Idiopathic Interstitial Pneumonias (1) · Lung Neoplasms (1)
Lung Diseases (10) · Respiratory Tract Diseases (10) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Infant, Newborn, Diseases (4) · Fibrosis (3) · Immune System Diseases (3) · Infant, Premature, Diseases (3) · Occupational Diseases (3) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Ventilator-Induced Lung Injury (3) · Cardiovascular Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Hypersensitivity (2)
Citrulline (1) · FAPI-46 (1) · Inhalation (1) · Magnetic Resonance Spectroscopy (1) · Metformin (1) · Positron Emission Tomography Computed Tomography (1) · Sulfur Hexafluoride (1) · gp100 Melanoma Antigen (1) · perflutren (1)
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (1) · HOHM Foundation (1) · Medical College of Wisconsin (1) · Peking Union Medical College Hospital (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Shanghai Zhongshan Hospital (1) · Thunder Bay Regional Health Research Institute (1) · University of California, Los Angeles (1) · University of Edinburgh (1) · University of Utah (1)
China (4) · United States (4) · Canada (1) · United Kingdom (1)
Alastair C Gray, PhD (1) · Candice Fike, MD (1) · Chris Haslett, MD (1) · David Newby, MD (1) · G. Ganesh Konduri, MD, MS (1) · Jeremie Calais, MD (1) · Jing Bi (1) · Kev Dhaliwal, MD (1) · Mitchell S Albert, PhD (1) · Tim Walsh, MD (1) · Yuanlin Song (1) · Zhaohui Zhu, MD (1)
PMID 12371452, PMID 17296674, PMID 24685414, PMID 28195659, PMID 28514023, PMID 33774816, PMID 35584850, PMID 35762891, PMID 35918725, PMID 36316628, PMID 37333204, PMID 37907796, PMID 39362770