614 completed, 62 terminated, 42 recruiting, 39 unknown. 817 Phase 1, 165 Phase 2.
Follow Lung Diseases, Obstructive: new trials by email Literature Review of Lung Diseases, Obstructive trials Research Report on Lung Diseases, Obstructive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| cfMSC Stem Cell Therapy Targeting COPD clonal fetal MSCs - Chronic Obstructive Pulmonary Disease (COPD) | Phase 1 / Phase 2 | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 30 | 2027-06-30 | 2026-08-27 |
| The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPD Inhaled Nitric Oxide, Placebo - Chronic Obstructive Pulmonary Disease | Phase 1 / Phase 2 | Not yet recruiting | University of Alberta | 80 | 2026-12-01 | 2026-07-08 |
| Anakinra Rescue Treatment for Moderate Asthma Attacks (ARTMA) Anakinra 100 Mg/0.67 Ml Inj Syringe, Saline Placebo/0.67 Ml Inj Syringe - Asthma (Diagnosis), Persistent Asthma | Phase 1 | Not yet recruiting | University of North Carolina, Chapel Hill | 60 | 2026-11-01 | 2026-07-15 |
| A Study of RO7830698 in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease RO7830698, Placebo - Chronic Obstructive Pulmonary Disease (COPD), Healthy Participants | Phase 1 / Phase 2 | Recruiting | Hoffmann-La Roche | 104 | 2026-10-20 | 2026-10-20 |
| Evaluation of Safety, Side Effects, and How the Drug, Inhaled CHF10136, Is Absorbed, Modified and Removed From the Body in Healthy Adults and Adults With Asthma CHF10136, CHF10136 matched placebo - Asthma, Healthy Volunteers | Phase 1 | Recruiting | Chiesi Farmaceutici S.p.A. | 120 | 2026-10-02 | 2026-10-13 |
| A Study to Investigate Small Mobile Stem Cells (SMS) in Moderate to Severe Chronic Obstructive Pulmonary Disease Stem cells - Chronic Obstructive Lung Disease | Phase 1 / Phase 2 | Not yet recruiting | SMSbiotech | 125 | 2026-10-01 | 2026-10-13 |
| A Randomized, Double-Blind, Placebo-Controlled Phase Ib Study of Multiple Ascending Doses of EB070 Injection in Adults With Moderate-to-Severe Asthma EB070 - Asthma | Phase 1 | Not yet recruiting | Biotech Pharmaceutical Co., Ltd. | 20 | 2026-09-30 | 2026-10-21 |
| A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in Children 1mg /kg VIC-1911 - GVHD (Acute or Chronic) | Phase 1 | Recruiting | Shanghai Jiao Tong University School of Medicine | 9 | 2026-09-28 | 2026-10-20 |
| Phase 1 PK Study of AERO-007, an Inhaled LABA+LAMA Combination for Nebulization Delivery in COPD Patients AERO-002 (60 mcg), Glycopyrrolate (18 mcg) - COPD (Chronic Obstructive Pulmonary Disease) | Phase 1 | Completed | AeroRx Therapeutics Inc. | 24 | 2026-09-21 | 2026-10-15 |
| Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations Metformin - Chronic Obstructive Pulmonary Disease (COPD) | Phase 1 | Not yet recruiting | Duke University | 45 | 2026-09-01 | 2026-04-29 |
| A Repeat Ascending Dosing Study of the Safety and Clinical Activity of R-3750 in Patients With Mild to Moderate COPD R-3750 - COPD (Chronic Obstructive Pulmonary Disease), COPD Exacerbation | Phase 1 | Not yet recruiting | Rise Therapeutics LLC | 27 | 2026-09-01 | 2026-01-29 |
| A Randomized, Phase Ib, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of SKB575 (HBM7575) in Participants With Asthma SKB575, Placebo - Asthma (Diagnosis) | Phase 1 | Recruiting | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 36 | 2026-08-25 | 2026-09-10 |
| A Study to Evaluate Pharmacokinetics, Safety, and Tolerability of Two GSK3862995B Formulations in Healthy Participants GSK3862995B - Pulmonary Disease, Chronic Obstructive | Phase 1 | Recruiting | GlaxoSmithKline | 24 | 2026-08-18 | 2026-09-01 |
| A Phase 1 Trial of AMG 691 in Healthy Chinese and Japanese Volunteers AMG 691 - Healthy Participants | Phase 1 | Recruiting | Amgen | 28 | 2026-08-07 | 2026-08-27 |
| Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants Belumosudil - Chronic Graft Versus Host Disease | Phase 1 | Not yet recruiting | Sanofi | 58 | 2026-08-06 | 2026-07-24 |
| A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of KIT2014 in Patients With Moderate to Severe COPD KIT2014, Placebo - Chronic Obstructive Pulmonary Disease (COPD) | Phase 1 / Phase 2 | Recruiting | Kither Biotech Srl | 36 | 2026-08-05 | 2026-10-20 |
| A Comparative Study to Investigate the Difference in Blood Levels of Two Different Formulations of GSK5784283 GSK5784283 - Asthma | Phase 1 | Recruiting | GlaxoSmithKline | 24 | 2026-07-17 | 2026-07-29 |
| A Phase I Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HRS-9821 Powder for Inhalation Administered as a Single Dose in Healthy Participants and Multiple Doses in Patients With COPD HRS-9821 Powder for Inhalation, Placebo - COPD | Phase 1 | Recruiting | Guangdong Hengrui Pharmaceutical Co., Ltd | 48 | 2026-07-09 | 2026-07-20 |
| A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function. AHB-137 injection - Chronic Hepatitis B | Phase 1 | Recruiting | Ausper Biopharma Co., Ltd. | 32 | 2026-07-09 | 2026-07-29 |
| A Study to Learn How Different Amounts of the Study Medicine Called PF-08103402 Are Tolerated and Act in the Body in Healthy Adults or Adults With Mild To-moderate Asthma PF-08103402, Placebo, Midazolam - Healthy Volunteer Study, Healthy Adults | Phase 1 | Recruiting | Pfizer | 133 | 2026-06-17 | 2026-10-13 |
Showing 20 of 817. Sign in to see all of them.
Asthma (397) · Pulmonary Disease, Chronic Obstructive (353) · Bronchiolitis Obliterans Syndrome (94) · Hypersensitivity (24) · Emphysema (18) · Lung Diseases (17) · Graft vs Host Disease (16) · Respiratory Aspiration (15) · Inflammation (13) · Rhinitis, Allergic (11) · Cystic Fibrosis (9) · Leukemia (9) · Bronchiolitis (8) · Bronchiolitis Obliterans (8) · Pulmonary Emphysema (8)
Respiratory Tract Diseases (811) · Lung Diseases (800) · Bronchial Diseases (509) · Immune System Diseases (492) · Pathological Conditions, Signs and Symptoms (406) · Respiratory Hypersensitivity (397) · Hypersensitivity, Immediate (396) · Pathologic Processes (389) · Hypersensitivity (375) · Disease Attributes (371) · Chronic Disease (369) · Bronchitis (111) · Bronchiolitis (100) · Organizing Pneumonia (94)
Budesonide (32) · Fluticasone (19) · Formoterol Fumarate (14) · Tiotropium Bromide (14) · Charcoal (13) · Albuterol (11) · Glycopyrrolate (11) · Inhalation (10) · montelukast (10) · Moxifloxacin (9) · Salmeterol Xinafoate (9) · Fluticasone-Salmeterol Drug Combination (8) · GSK573719 (7) · fluticasone furoate (7) · vilanterol (7)
GlaxoSmithKline (141) · AstraZeneca (58) · Chiesi Farmaceutici S.p.A. (29) · Boehringer Ingelheim (14) · Orion Corporation, Orion Pharma (13) · Pfizer (13) · Merck Sharp & Dohme LLC (12) · University of North Carolina, Chapel Hill (12) · Amgen (10) · MedImmune LLC (10) · Novartis (9) · Novartis Pharmaceuticals (9) · Hoffmann-La Roche (8) · Pearl Therapeutics, Inc. (8) · Teva Branded Pharmaceutical Products R&D, Inc. (8)
United States (288) · United Kingdom (171) · Germany (79) · China (66) · Australia (51) · Belgium (20) · Canada (20) · New Zealand (19) · Netherlands (15) · Japan (11) · Finland (10) · France (10) · Poland (10) · Spain (10) · Israel (9)
Michelle Hernandez, MD (5) · Robert Wood, MD (5) · Cecil Charles, PhD (4) · Dave Singh (4)
PMID 24184147, PMID 22793945, PMID 33152467, PMID 16235359, PMID 16565429, PMID 16636091, PMID 16690673, PMID 17132052, PMID 17507545, PMID 18073405, PMID 21975749, PMID 22314182, PMID 22793939, PMID 23074435, PMID 23076942, PMID 23235687, PMID 23256721, PMID 23364286, PMID 2337756, PMID 23992090, PMID 24563632, PMID 24615270, PMID 25450456, PMID 26092545, PMID 26372465, PMID 26372467, PMID 26620151, PMID 29149867, PMID 29550052, PMID 29856004, PMID 30425469, PMID 32071044, PMID 32907575, PMID 36184023, PMID 40185989, PMID 40391696, PMID 41677208, PMID 10048682, PMID 11163535, PMID 11728816, PMID 11815760, PMID 12493340, PMID 12543832, PMID 14757603, PMID 15764724, PMID 16164444, PMID 16186597, PMID 16611654, PMID 17015575, PMID 1731020
2015 (10), 2016 (9), 2014 (6), 2017 (6), 2019 (6), 2023 (6), 2018 (5), 2008 (4), 2009 (4), R01HL135235 (3), P01AT002620 (2), P01AT002647 (2), P01HL158507 (2), U19AI095261 (2), K76AG095138 (1)