983 completed, 149 terminated, 95 recruiting, 91 unknown. 1449 Phase 2, 167 Phase 1, 109 Phase 3.
Follow Lung Diseases, Obstructive: new trials by email Literature Review of Lung Diseases, Obstructive trials Research Report on Lung Diseases, Obstructive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| cfMSC Stem Cell Therapy Targeting COPD clonal fetal MSCs - Chronic Obstructive Pulmonary Disease (COPD) | Phase 1 / Phase 2 | Not yet recruiting | Shenzhen Geno-Immune Medical Institute | 30 | 2027-06-30 | 2026-11-02 |
| Effect of Linvemastat in Patients With Partially Controlled Asthma (syMMPonia) linvemastat, Placebo - Asthma (Diagnosis), Pulmonary Function | Phase 2 | Not yet recruiting | Foresee Pharmaceuticals Co., Ltd. | 135 | 2027-03-01 | 2026-07-20 |
| An Open-Label Extension Study to Evaluate Inhaled Treprostinil SMI in Participants With Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD) treprostinil SMI (treprostinil inhalation spray) - Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease | Phase 2 / Phase 3 | Not yet recruiting | United Therapeutics | 400 | 2027-03-01 | 2026-11-06 |
| Preventing Childhood Asthma Using Prophylactic House Dust Mite Allergen Immunotherapy HDM sublingual Immunotherapy, Placebo - Asthma, Allergy | Phase 2 | Withdrawn | Boston Children's Hospital | 2027-02-01 | 2024-11-26 | |
| Efficacy and Safety of Slow Release Dehydroepiandrosterone (DHEA ) Slow Release DHEA, Placebo - Asthma | Phase 2 | Not yet recruiting | Indiana University | 30 | 2027-01-01 | 2026-02-27 |
| Nebulized Ketamine for Severe Asthma Attacks in Children Ketamine (1 mg/kg), Placebo - Asthma Acute, Exacerbation of Allergic Asthma | Phase 2 | Not yet recruiting | Sultan Qaboos University | 60 | 2027-01-01 | 2026-07-27 |
| The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPD Inhaled Nitric Oxide, Placebo - Chronic Obstructive Pulmonary Disease | Phase 1 / Phase 2 | Not yet recruiting | University of Alberta | 80 | 2026-12-01 | 2026-07-08 |
| A Clinical Trial Comparing TQC3927 Inhaled Powder With Glycopyrronium Bromide and Formoterol Inhaled Aerosol (Biovoping® Lingchang®) for the Treatment of Chronic Obstructive Pulmonary Disease TQC3927 inhalation aerosol, Glyceryl bromide/formoterol inhalation aerosol - Chronic Obstructive Pulmonary Disease | Phase 2 | Suspended | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 90 | 2026-12-01 | 2026-09-03 |
| A Study to Assess the Efficacy and Safety of Co-administration of GSK3862995B With GSK5784283 in Adult Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) GSK3862995B, GSK5784283, Placebo - Pulmonary Disease, Chronic Obstructive | Phase 2 | Not yet recruiting | GlaxoSmithKline | 279 | 2026-11-09 | 2026-11-04 |
| Urolithin A Supplementation During Pulmonary Rehabilitation in Patients With COPD Urolithin A, Placebo - Chronic Obstructive Pulmonary Disease (COPD) | Phase 2 | Not yet recruiting | Bryan A. Ross | 198 | 2026-11-01 | 2026-10-13 |
| Ginger's Therapeutic Potential in Asthma Ginger Extract, Placebo - Asthma | Phase 2 | Not yet recruiting | Emily DiMango, MD | 32 | 2026-11-01 | 2026-08-28 |
| Study of Treprostinil Administered Via Soft Mist Inhaler (SMI) in Participants With Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD) treprostinil SMI (treprostinil inhalation spray), Placebo (placebo inhalation spray) - Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease | Phase 2 | Not yet recruiting | United Therapeutics | 40 | 2026-11-01 | 2026-11-06 |
| A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB) AHB-137, TVAX-008, Placebo - Chronic Hepatitis B | Phase 1 / Phase 2 | Not yet recruiting | Grand Theravac Life Sciences (Hangzhou) Co., Ltd. | 105 | 2026-10-31 | 2026-10-27 |
| A Study of RO7830698 in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease RO7830698, Placebo - Chronic Obstructive Pulmonary Disease (COPD), Healthy Participants | Phase 1 / Phase 2 | Recruiting | Hoffmann-La Roche | 104 | 2026-10-20 | 2026-10-20 |
| A Study to Investigate the Efficacy and Safety of Zelicapavir Compared With Placebo in Adults With RSV Who Are at High Risk for Severe Disease zelicapavir, Placebo - RSV | Phase 2 / Phase 3 | Recruiting | Enanta Pharmaceuticals, Inc | 860 | 2026-10-19 | 2026-11-02 |
| A Study of JNJ-95597528 in Participants With Inadequately Controlled Moderate to Severe Asthma JNJ-95597528, Placebo - Asthma | Phase 2 | Recruiting | Janssen Research & Development, LLC | 440 | 2026-10-05 | 2026-11-03 |
| A Study to Investigate Small Mobile Stem Cells (SMS) in Moderate to Severe Chronic Obstructive Pulmonary Disease Stem cells - Chronic Obstructive Lung Disease | Phase 1 / Phase 2 | Not yet recruiting | SMSbiotech | 125 | 2026-10-01 | 2026-10-13 |
| Phase 2b Efficacy and Safety Study of AERO-007, an Inhaled LABA+LAMA Combination for Nebulization Delivery in COPD Patients AERO-001, AERO-002, AERO-007 - COPD, Chronic Obstructive Pulmonary Disease (COPD) | Phase 2 | Recruiting | AeroRx Therapeutics Inc. | 64 | 2026-10-01 | 2026-10-28 |
| GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD Tirzepatide - COPD, Obesity & Overweight | Phase 2 | Not yet recruiting | The Cleveland Clinic | 30 | 2026-08-28 | 2026-08-05 |
| PRA-216 COPD Safety and Biomarker Study PRA-216, Placebo - Chronic Obstructive Pulmonary Disease (COPD) | Phase 2 | Recruiting | Prana Therapies Inc | 40 | 2026-08-25 | 2026-10-28 |
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Asthma (667) · Pulmonary Disease, Chronic Obstructive (552) · Bronchiolitis Obliterans Syndrome (205) · Emphysema (56) · Lung Diseases (45) · Bronchitis, Chronic (36) · Dyspnea (30) · Hypersensitivity (29) · Graft vs Host Disease (27) · Bronchiolitis (26) · Bronchiolitis Obliterans (22) · Inflammation (22) · Respiratory Aspiration (22) · Respiratory Tract Diseases (22)
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Formoterol Fumarate (61) · Tiotropium Bromide (45) · Fluticasone (39) · montelukast (35) · Albuterol (34) · Salmeterol Xinafoate (24) · Budesonide (22) · indacaterol (21) · Glycopyrrolate (17) · Beclomethasone (16) · Omalizumab (15) · Saline Solution (15) · Cholecalciferol (14) · Fluticasone-Salmeterol Drug Combination (13) · Mometasone Furoate (12)
GlaxoSmithKline (103) · AstraZeneca (72) · Boehringer Ingelheim (58) · Novartis Pharmaceuticals (58) · Chiesi Farmaceutici S.p.A. (41) · Novartis (23) · Pfizer (21) · Merck Sharp & Dohme LLC (16) · Pearl Therapeutics, Inc. (16) · MedImmune LLC (14) · Sanofi (14) · Dey (12) · Genentech, Inc. (12) · Teva Branded Pharmaceutical Products R&D, Inc. (12) · National Institute of Allergy and Infectious Diseases (NIAID) (11)
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