6 active not recruiting, 5 recruiting, 3 completed, 3 enrolling by invitation. 10 Not applicable, 2 Phase 3, 1 Early Phase 1, 1 Phase 1, 1 Phase 2.
Follow Longevity: new trials by email Literature Review of Longevity trials Research Report on Longevity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life Psilocybin (Usona Institute) - Aging, Longevity | Phase 1 | Not yet recruiting | Charles Raison | 50 | 2026-12-01 | 2026-10-13 |
| "ADEN Platform: Pilot Clinical Validation for Chronic Disease Risk Stratification in Colombia" Molecular Target - Preventive Cardiology, Respiration Disorders | Enrolling by invitation | Unidad de Investigación Genética Molecular | 120 | 2026-08-01 | 2026-07-27 | |
| Registry of Outcomes of Dezawa MuseCells® MuseCell Treatment - Osteoarthritis (OA), Longevity | Recruiting | MuseCell Innovations Pte LTD | 5000 | 2026-07-01 | 2026-06-12 | |
| Collagen Peptides and Cellular Aging Collagen peptides, Maltodextrin (Placebo) - Longevity, Healthy Aging | Not applicable | Recruiting | University of Vienna | 125 | 2026-04-22 | 2026-05-05 |
| The Effects of PeptiStrong and Whey on Muscle Function In Older Adults PeptiStrong + whey protein, Whey protein - Healthy Ageing, Protein Supplementation | Not applicable | Active not recruiting | Nuritas Ltd | 81 | 2026-04-06 | 2026-09-28 |
| Food Supplement for Longevity Longevity supplement - Healthy Adult, Longevity | Not applicable | Active not recruiting | Sam Treadway | 18 | 2026-03-06 | 2026-06-22 |
| L-serine and Strength Training in the Elderly Strength training, L-serine supplementation, Control (cornstarch) - Brain Health, Longevity | Not applicable | Recruiting | University of Vienna | 126 | 2026-03-01 | 2026-03-12 |
| A Real-World Evidence Study Evaluating the Effects of the Human Optimization Project Protocol on Methylation Biomarkers and Health-Related Quality of Life in Women Human Optimization Project - Longevity, Women's Health | Not applicable | Active not recruiting | Human Optimization Project | 35 | 2026-03-01 | 2026-04-23 |
| Kaempferol Absorption and Pharmacokinetics Evaluation Kaempferol - No Disease, Mitochondria Health | Not applicable | Recruiting | University of Pittsburgh | 120 | 2025-12-09 | 2026-03-23 |
| Effects of a Multi-Targeted Oral Supplement on Skin, Hair, Sleep, Energy, Cognition, Libido and Epigenetic Biological Clock Age Advanced ID, Placebo Control - Skin Ageing, Healthy Ageing | Not applicable | Active not recruiting | IDI Skincare Limited | 64 | 2025-12-08 | 2026-10-16 |
| Iterative Design Trial to Assess Dietary Supplements and Other Aging-targeted Therapies Spermidine - Aging, Longevity | Not applicable | Enrolling by invitation | Atria Research and Global Health Institute (ARGHI) | 10 | 2025-09-01 | 2025-10-01 |
| Combination Gerotherapeutic Interventions for Healthspan Improvement Rapamycin, Naltrexone, Metformin - Healthspan Improvement, Aging | Phase 3 | Active not recruiting | AgelessRx | 30 | 2025-07-23 | 2026-03-16 |
| Clinical Evaluation on the Longevity of Glass Ceramic Based Single Tooth Restorations Single tooth restoration with IPS e.max - Single Tooth Restoration, Longevity | Completed | Ivoclar Vivadent AG | 56 | 2025-05-23 | 2026-06-09 | |
| Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation Metformin, Rapamycin, Naltrexone - Longevity, GLP-1 | Phase 2 / Phase 3 | Recruiting | AgelessRx | 150 | 2024-12-17 | 2025-07-30 |
| Effectiveness of Microdosed GLP-1 in Improving Health, Quality of Life, and Longevity Measures GLP-1, Placebo - Longevity, Quality of Life | Early Phase 1 | Enrolling by invitation | AgelessRx | 150 | 2024-11-01 | 2025-07-30 |
| Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men 4g of taurine daily, Placebo - Taurine, Aging, Biological | Not applicable | Completed | Technical University of Munich | 90 | 2024-09-25 | 2025-11-21 |
| Multi-Modal Longevity Protocol Including Autologous Cell-Free Conditioned Media Multi-Modal Longevity Protocol - Biological Aging, Healthy Aging | Not applicable | Completed | BlueBird Age Reversal SA | 15 | 2024-08-05 | 2026-01-07 |
| Longevity Families of the Netherlands Longevity, Familial Longevity | Active not recruiting | Leiden University Medical Center | 600 | 2023-09-11 | 2026-08-26 |
Inflammation (2) · Agnosia (1) · Motor Activity (1) · Osteoarthritis (1) · Pain (1) · Respiration Disorders (1) · Sleep Initiation and Maintenance Disorders (1) · Wounds and Injuries (1)
Nervous System Diseases (2) · Neurologic Manifestations (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Arthritis (1) · Behavior (1) · Dyssomnias (1) · Joint Diseases (1) · Mental Disorders (1) · Musculoskeletal Diseases (1) · Neurobehavioral Manifestations (1) · Perceptual Disorders (1) · Respiratory Tract Diseases (1) · Rheumatic Diseases (1)
Metformin (2) · Naltrexone (2) · Sirolimus (2) · Ascorbic Acid (1) · Glucagon-Like Peptide 1 (1) · Glutathione (1) · NAD (1) · Psilocybin (1) · Resistance Training (1) · Spermidine (1) · Starch (1) · Vitamin B 12 (1) · Whey Proteins (1) · kaempferol (1) · maltodextrin (1)
AgelessRx (3) · University of Vienna (2) · Atria Research and Global Health Institute (ARGHI) (1) · BlueBird Age Reversal SA (1) · Charles Raison (1) · Human Optimization Project (1) · IDI Skincare Limited (1) · Ivoclar Vivadent AG (1) · Leiden University Medical Center (1) · MuseCell Innovations Pte LTD (1) · Nuritas Ltd (1) · Sam Treadway (1) · Technical University of Munich (1) · Unidad de Investigación Genética Molecular (1) · University of Pittsburgh (1)
United States (8) · United Kingdom (4) · Austria (2) · Colombia (1) · Germany (1) · Liechtenstein (1) · Mexico (1) · Netherlands (1)
Stefanie Morgan, PhD (2) · Afshin Beheshti, PhD (1) · Esteban Ortega, MD (1) · Graeme Close, Professor (1) · Jenell Decker, MD (1) · Juan M Anaya, MD,PhD, internista reumatologo (1)