12 completed, 4 terminated, 3 recruiting, 2 unknown. 22 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 22 | Completed 12, Terminated 4, Recruiting 3, Unknown 2, Enrolling by invitation 1 |
Follow Long QT Syndrome: new trials by email Literature Review of Long QT Syndrome trials Research Report on Long QT Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Frequency of Hypoglycemia in Children With Beta-blocker Treated Long QT-syndrome Continuous Glucose Monitoring - Long QT Syndrome, Hypoglycemia | Not applicable | Enrolling by invitation | Helsinki University Central Hospital | 40 | 2024-12-09 | 2025-11-18 |
| Breath-holding Spells and Its Management Study Guidelines - Breath-holding Spell | Not applicable | Recruiting | Region Skane | 120 | 2024-12-02 | 2026-05-05 |
| Continuous Versus Intermittent cARdiac Electrical moNitorinG BodyGuardian Mini Plus - Torsades de Pointe Caused by Drug, Long QT Syndrome | Not applicable | Recruiting | Washington University School of Medicine | 60 | 2023-11-21 | 2025-12-30 |
| Comparing Direct vs Indirect Methods for Cascade Screening Direct contact of family members for cascade screening of relevant variants - Long QT Syndrome, Familial Hypercholesterolemia | Not applicable | Recruiting | University of Maryland, Baltimore | 200 | 2023-05-15 | 2026-04-14 |
| QT Changes in Geriatric Patients: a Comparison of Spinal and General Anesthesia QT and QTc interval - Anesthesia, Spinal, Sevoflurane | Not applicable | Completed | Haseki Training and Research Hospital | 58 | 2023-03-29 | 2024-04-19 |
| Beat to Beat A Study in Paediatric, Adolescent and Young Adult Patients Who Are Undergoing or Have Undergone Cancer Therapy to Evaluate the Agreement Between QTc Measured Using 12 Lead Electrocardiogram (ECG) and a Wearable Device ECG ECG application, 12 lead ECG - Neoplasms, Cardiac Arrhythmia | Not applicable | Completed | Murdoch Childrens Research Institute | 45 | 2023-02-07 | 2025-04-01 |
| Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations MRI - Long QT Syndrome, Brugada Syndrome | Not applicable | Completed | University Hospital, Montpellier | 214 | 2021-02-01 | 2026-06-18 |
| Evaluation of the Effects of KCNQ1 Mutation on Insulin Tolerance and Obsessive Compulsive Features in Long QT Romano-Ward Syndrome Patients. Cognitive assessment of obsessive-compulsive and impulsive behaviours, Genomic analysis, Glucoregulation assessment - Romano-Ward Syndrome, Long QT Syndrome | Not applicable | Unknown | Biotrial | 100 | 2021-01-08 | 2021-01-20 |
| Measurement of the Electromechanical Window to Improve the Diagnosis of Congenital Long QT Syndrome ECG coupled to phonocardiography - Long QT Syndrome | Not applicable | Completed | University Hospital, Bordeaux | 224 | 2020-08-28 | 2025-06-17 |
| Long QT Syndrome and Sleep Apnea Continuous Positive Airway Pressure (CPAP) - Long QT Syndrome, Sleep Apnea | Not applicable | Completed | The Cleveland Clinic | 9 | 2019-03-13 | 2020-07-02 |
| KCNQ1 Cascade Screening Simplified Cascade Screening - Long QT Syndrome | Not applicable | Terminated | University of Maryland, Baltimore | 131 | 2019-03-07 | 2023-06-27 |
| The Effect of Energy Drink on Cardiovascular Variables: A Randomized Controlled Trial Energy drink, Placebo drink - Cardiovascular Diseases | Not applicable | Completed | University of the Pacific | 20 | 2019-02-23 | 2019-09-25 |
| Low Cost QTc Meter for Long QT Syndrome Screening in Primary Care QTc Meter - Long QT Syndrome | Not applicable | Terminated | Mayo Clinic | 33 | 2019-02-07 | 2023-07-25 |
| The Physiological Effects of Human Ether-a-go-go-Related Gene (hERG)Blockade on Metabolism Moxifloxacin, Placebo - Long QT Syndrome, Hypoglycemia | Not applicable | Completed | Signe Torekov | 44 | 2019-01-28 | 2022-04-14 |
| Exploring Mechanisms and Morphology of QT Interval Prolongation Beta Blockers, Spironolactone - Long Qt Syndrome 1-2, Sudden Cardiac Death | Not applicable | Completed | Herlev and Gentofte Hospital | 28 | 2017-06-27 | 2019-02-21 |
| Effect of Grapefruit on QT Interval in Healthy Volunteers and Patients With Congenital Long QT Syndrome Moxifloxacin, Grapefruit group - Long QT Syndrome | Not applicable | Completed | Tel-Aviv Sourasky Medical Center | 25 | 2016-12-01 | 2019-05-24 |
| Abnormal QT-Response to the Sudden Tachycardia Provoked by Standing in Individuals With Drug-induced Long QT Syndrome tilt table - Long QT Syndrome | Not applicable | Completed | Tel-Aviv Sourasky Medical Center | 5 | 2016-01-01 | 2018-02-15 |
| Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies Dental restorative procedure - Channelopathies, Brugada Syndrome | Not applicable | Completed | University of Sao Paulo General Hospital | 31 | 2015-05-01 | 2024-04-09 |
| Comparison Between Epinephrine and Exercise Test in QT Long Syndrome Patients exercise test, Epinephrine test - Long QT Syndrome Type 1 or 2 | Not applicable | Unknown | Nantes University Hospital | 130 | 2012-05-01 | 2016-10-05 |
| Low-dose Epinephrine Infusion Tests in Adolescent and Pediatric Patients Epinephrine - Congenital Disorders | Not applicable | Terminated | Emory University | 7 | 2008-02-01 | 2017-12-06 |
Showing 20 of 22. Sign in to see all of them.
Arrhythmias, Cardiac (2) · Brugada Syndrome (2) · Death, Sudden, Cardiac (2) · Hypoglycemia (2) · Motor Activity (2) · Romano-Ward Syndrome (2) · Tachycardia, Ventricular (2) · Anemia, Iron-Deficiency (1) · Arrhythmogenic Right Ventricular Dysplasia (1) · Cardiomyopathies (1) · Cardiomyopathy, Dilated (1) · Cardiomyopathy, Hypertrophic (1) · Cardiomyopathy, Restrictive (1) · Cardiovascular Diseases (1)
Cardiac Conduction System Disease (22) · Cardiovascular Abnormalities (22) · Congenital Abnormalities (22) · Heart Diseases (22) · Pathologic Processes (22) · Pathological Conditions, Signs and Symptoms (22) · Cardiovascular Diseases (21) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (21) · Heart Defects, Congenital (21) · Arrhythmias, Cardiac (20) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Behavior (3) · Death (3) · Genetic Diseases, Inborn (3)
Moxifloxacin (2) · Adrenergic beta-Antagonists (1) · Continuous Glucose Monitoring (1) · Continuous Positive Airway Pressure (1) · Electrocardiography (1) · Energy Drinks (1) · Epinephrine (1) · Exercise Test (1) · Spironolactone (1) · Tilt-Table Test (1)
Tel-Aviv Sourasky Medical Center (2) · University of Maryland, Baltimore (2) · Biotrial (1) · Charles Berul (1) · Emory University (1) · Haseki Training and Research Hospital (1) · Helsinki University Central Hospital (1) · Herlev and Gentofte Hospital (1) · Mayo Clinic (1) · MetroHealth Medical Center (1) · Murdoch Childrens Research Institute (1) · Nantes University Hospital (1) · Region Skane (1) · Signe Torekov (1) · The Cleveland Clinic (1)
United States (8) · France (4) · Denmark (2) · Israel (2) · Australia (1) · Brazil (1) · Finland (1) · Sweden (1) · Turkey (Türkiye) (1)
Ana CG Oliveira, S (1) · Cesar J Gruppi, PhD (1) · Charles I Berul, MD (1) · Cynthia Lee, PharmD (1) · Denise Hachul, PhD (1) · Ehud Chorin, MD (1) · Elina Hakonen, MD, PhD (1) · Elizabeth S Kaufman, MD (1) · Francisco CC Darrieux, PhD (1) · Itamara LI Neves, PhD (1) · Joshua D Mitchell, M.D., FACC (1) · Luciana Sacilotto, S (1)
PMID 23694966, PMID 28083030, PMID 31075442, PMID 31319747, PMID 32882399, PMID 34531279, PMID 39998828
2023 (1), R21HG010412 (1)