107 completed, 48 recruiting, 39 unknown, 19 active not recruiting. 105 Not applicable, 59 Phase 2, 16 Phase 3, 8 Phase 1, 1 Early Phase 1.
Follow Long COVID: new trials by email Literature Review of Long COVID trials Research Report on Long COVID
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Taurine Supplementation in Adolescents With Post-COVID Condition Taurine - Long COVID, Post COVID-19 Condition | Phase 1 / Phase 2 | Not yet recruiting | University of Alberta | 30 | 2026-12-30 | 2026-10-16 |
| Fatigue in Long COVID Lightning Process, Activity Pacing - Long COVID | Not applicable | Not yet recruiting | McMaster University | 100 | 2026-11-01 | 2026-07-13 |
| Study of VYD2311 for the Treatment of Adults With Long-COVID or Post-Vaccination Syndrome VYD2311, Placebo - Long COVID, COVID-19 (SARS-CoV-2 Infection) | Phase 2 | Not yet recruiting | Invivyd, Inc. | 130 | 2026-10-01 | 2026-10-27 |
| Transcranial Direct Current Stimulation for Long COVID Brain Fog and Fatigue Transcranial Direct Current Stimulation - Long COVID, Post-COVID Conditions | Not applicable | Not yet recruiting | University of Las Palmas de Gran Canaria | 20 | 2026-09-15 | 2026-07-22 |
| Five-year Follow-up After Sars-CoV-2 Infection: Prevalence and Evolution of Post-acute Sequalae of COVID-19 (PASC) Post-Acute Sequelae of COVID-19 (PASC) Assessment - Long COVID, COVID-19 | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 900 | 2026-09-01 | 2026-08-14 | |
| Observational Study of Intranasal IVIG in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Patients Undergoing Medical Tourism Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID | Not yet recruiting | Tamara C Tamas | 50 | 2026-08-01 | 2025-12-02 | |
| Sauna for Long Covid whole body hyperthermia - Long COVID | Not applicable | Recruiting | Massachusetts General Hospital | 21 | 2026-08-01 | 2025-11-13 |
| Cognitive Impairment and Return to Work in Long COVID Long COVID | Completed | Hopitaux de Saint-Maurice | 55 | 2026-08-01 | 2026-10-19 | |
| A Pilot Randomized Controlled Trial of Homeopathic Treatment for Long COVID Treatment A: Treatment by a homeopath prescribing a specific homeopathic remedy for long COVID, a course of individually tailored treatment by a homeopath - Long COVID, Long COVID Symptoms | Not applicable | Not yet recruiting | St. Mary's University, Twickenham | 120 | 2026-07-15 | 2026-07-09 |
| A Multi-Center, Individually-Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Superiority Trial to Evaluate the Efficacy of the Combination of Maraviroc and Atorvastatin for the Treatment of Subjects With Long COVID Maraviroc (MVC), Atorvastatin, 10mg, 20mg, 40mg, Placebo, Maraviroc - Long COVID | Phase 2 / Phase 3 | Not yet recruiting | HealthBio, Inc. | 252 | 2026-07-15 | 2026-06-18 |
| Development of an Accessible Cognitive Behavioral Therapy Digital Therapeutic for Individuals With Long COVID Rauha® Digital Therapeutic Platform (Toivoa-004) - Long Covid, Depression | Not applicable | Withdrawn | Toivoa Inc | 2026-07-01 | 2026-07-29 | |
| SARS-CoV-2 and Herpesvirus Inhibition for Ending Long COVID Dysfunction Valacyclovir, Celecoxib, Paxlovid - Post-acute Sequelae of COVID-19, Long COVID | Phase 2 | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 150 | 2026-06-01 | 2026-05-19 |
| Fatigue Investigation Using Digital Outcomes Multiple Sclerosis, Long Covid | Recruiting | Liliana Barrios | 122 | 2026-05-26 | 2026-08-24 | |
| Evaluating the Safety and Efficacy of PNMR as Treatment for Long COVID Paragon Novel Metabolic Regulator (PNMR), Dietary and Lifestyle Recommendations - Long COVID | Phase 2 | Recruiting | ParagonClinicals Inc. | 82 | 2026-05-20 | 2026-06-04 |
| Validation of Biomarkers for Long COVID in the LIINC Viral Immunopathogenesis and Persistence Repeat Donor Cohort (VIPER) Long Covid | Recruiting | University of California, San Francisco | 150 | 2026-05-18 | 2026-08-18 | |
| Understanding the Long-term Impact of COVID-19 in Adults Long COVID, Long Covid19 | Not yet recruiting | NYU Langone Health | 5205 | 2026-05-01 | 2026-03-27 | |
| The Effect of Acupuncture Treatment on Cognitive Functions and Brain Networks for Long COVID Acupuncture, Sham acupuncture - Long Covid | Not applicable | Not yet recruiting | Tingting Luo | 108 | 2026-05-01 | 2026-01-21 |
| PERCEIVE-Outreach: A Scalable, Risk-Based Model for Managing Persistent Cardiovascular Impact in Long COVID PERCEIVE-Outreach Disease Management Program - Long COVID | Not applicable | Recruiting | University of Tasmania | 577 | 2026-04-01 | 2026-10-06 |
| A Study of Human Umbilical Cord Blood (REGENECYTE) Infusion in Patients With Post-COVID Condition REGENECYTE, Placebo - Long COVID, Post-COVID-19 Condition | Phase 3 | Not yet recruiting | StemCyte, Inc. | 60 | 2026-03-31 | 2025-09-23 |
| Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease Kisspeptin 112-121 - Reproductive Disorder, Neurodegeneration | Phase 1 | Recruiting | Stephanie B. Seminara, MD | 40 | 2026-03-10 | 2026-07-13 |
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Post-Acute COVID-19 Syndrome (244) · COVID-19 (57) · Fatigue (18) · Mental Fatigue (18) · Motor Activity (14) · Fatigue Syndrome, Chronic (12) · Cognitive Dysfunction (8) · Depression (7) · Postural Orthostatic Tachycardia Syndrome (7) · Anxiety Disorders (6) · Asthma (6) · Autonomic Nervous System Diseases (6) · Dyspnea (6) · Multiple Sclerosis (5) · Pain (5)
Coronaviridae Infections (244) · Disease Attributes (244) · Lung Diseases (244) · Nidovirales Infections (244) · Pathologic Processes (244) · Pathological Conditions, Signs and Symptoms (244) · Pneumonia (244) · Pneumonia, Viral (244) · RNA Virus Infections (244) · Respiratory Tract Infections (244) · Virus Diseases (244) · Chronic Disease (243) · Infections (243) · Post-Infectious Disorders (243) · Respiratory Tract Diseases (243)
Educational Status (4) · Ritonavir (4) · Acupuncture Therapy (3) · Blood Specimen Collection (3) · Hyperbaric Oxygenation (3) · Transcranial Direct Current Stimulation (3) · nirmatrelvir and ritonavir drug combination (3) · ALT-803 (2) · Amantadine (2) · Bupivacaine (2) · Cognitive Training (2) · Exercise (2) · Immunoglobulins, Intravenous (2) · Ivabradine (2) · Lithium (2)
Duke University (8) · Icahn School of Medicine at Mount Sinai (5) · Kanecia Obie Zimmerman (5) · VA Office of Research and Development (5) · University of Alberta (4) · StemCyte, Inc. (3) · University Health Network, Toronto (3) · Beth Israel Deaconess Medical Center (2) · Centre for Addiction and Mental Health (2) · Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec (2) · Chengdu Sport University (2) · European University Cyprus (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · ImmunityBio, Inc. (2) · Karolinska Institutet (2)
United States (96) · Canada (18) · United Kingdom (15) · Spain (13) · Italy (12) · Brazil (8) · China (7) · Germany (7) · Austria (5) · Belgium (5) · France (5) · Netherlands (5) · Switzerland (5) · Mexico (4) · Taiwan (4)
Lucinda Bateman, MD (4) · Barry Make, MD (3) · Christina Barkauskas, MD (3) · Cyndya Shibao, MD (3) · Gary M Felker, MD (3) · Janna Friedly, MD, MPH (3) · Kanecia Zimmerman, MD PhD (3) · Pam Taub, MD (3) · Peter Novak, MD (3) · Susan Redline, MD MPH (3) · Tae Chung, MD (3) · Angela M Cheung, MD, PhD (2) · Christopher Grainger, MD (2) · Daniel Laskowitz, MD MHS (2) · David Putrino, PhD, PT (2)
PMID 41720282, PMID 42282195, PMID 39356507, PMID 32644129, PMID 35059791, PMID 35571200, PMID 35816681, PMID 36446465, PMID 36806073, PMID 36833793, PMID 37270195, PMID 37868959, PMID 38102536, PMID 38173937, PMID 38755688, PMID 38802273, PMID 38848477, PMID 38879571, PMID 39493634, PMID 39536121, PMID 39571342, PMID 39592468, PMID 40188838, PMID 40334212, PMID 40495009, PMID 40622772, PMID 40730806, PMID 40810942, PMID 40894014, PMID 40940063, PMID 41212544, PMID 41253410, PMID 41316170, PMID 41625963, PMID 41650882, PMID 41748706, PMID 42017829, PMID 42118816, PMID 42136829, PMID 42243809, PMID 42415194, PMID 42447127, PMID 42498469, PMID 42533000, PMID 42547235, PMID 42577968, PMID 42653699, PMID 42673984, PMID 42790915
OT2HL156812 (3), 1OT2HL156812-01 (1), 2023 (1), 272201800011C-P00005-9999-1 (1), I01CX002668 (1), I21RX004092 (1), I21RX004409 (1), R01AG085873 (1), R01AG089307 (1), R01DC021179 (1), R34AT012679 (1), R37HD043341 (1), R43NR021082 (1), UL1TR001412 (1)