21 completed. 21 Phase 2, 5 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 21 | Completed 21 |
| Phase 1 | 5 | Completed 5 |
| Phase 3 | 1 | Completed 1 |
Follow Lip Diseases: new trials by email Literature Review of Lip Diseases trials Research Report on Lip Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene A166 - HER2-positive Breast Cancer, HER2 Gene Mutation | Phase 1 / Phase 2 | Completed | Klus Pharma Inc. | 49 | 2018-07-16 | 2023-08-03 |
| Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma Cetuximab, Ficlatuzumab - Head and Neck Basaloid Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma | Phase 2 | Completed | University of Arizona | 78 | 2017-12-05 | 2024-09-04 |
| Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for Episodic Treatment of Cold Sores Merlin, Ethanol - Recurrent Herpes Labialis | Phase 2 | Completed | Topical Remedy | 451 | 2017-07-05 | 2018-09-12 |
| Double-blind, Vehicle-controlled Study of the Efficacy and Safety of SADBE in Subjects With Recurrent Herpes Labialis SADBE, Placebo - Herpes Labialis, Cold Sore | Phase 1 / Phase 2 | Completed | Squarex, LLC | 139 | 2016-12-01 | 2021-11-02 |
| Trial on Efficacy and Safety of Pritelivir Ointment for Treatment of Labial Herpes Pritelivir 5% w/w ointment, Pritelivir ointment matching placebo, Zovirax® cream - Herpes Labialis | Phase 2 | Completed | AiCuris Anti-infective Cures AG | 362 | 2016-11-29 | 2021-07-13 |
| Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair Botulinum Toxin Type A, Normal Saline Injection - Cleft Lip, Scarring | Phase 1 / Phase 2 | Completed | The University of Texas Health Science Center, Houston | 30 | 2015-12-01 | 2021-11-03 |
| Safety, Tolerability and Therapeutic Efficacy of Topical ZEP-3 Ointment (1.0%) for the Treatment of Cold Sores ZEP-3 ointment 1.0%, Acyclovir cream 5% - Herpes Labialis | Phase 2 | Completed | Shulov Innovate for Science Ltd. 2012 | 210 | 2015-09-01 | 2019-05-30 |
| Description of Pain in Pediatric Patients With Cleft Lip and Palate Undergoing Alveolar Grafting Using Two Surgical Strategies: Stem Cells and Autogenous Iliac Crest Bone (Pain Evaluation in Children Undergoing Alveolar Grafting: Stem Cells vs. Iliac Crest Bone) Autogenous Iliac Crest Bone Grafting, Bioengineered Alveolar Grafting (SHED + Scaffold) - Clift Lip, Cleft Palate | Phase 1 / Phase 2 | Completed | Hospital Sirio-Libanes | 20 | 2015-03-01 | 2026-07-29 |
| A Double-Blind, Randomized, Placebo-Controlled Study of Topical VDO for the Treatment of Herpes Simplex Labialis VDO gel, placebo - Herpes Labialis | Phase 2 | Completed | Yung Shin Pharm. Ind. Co., Ltd. | 40 | 2014-07-01 | 2016-04-15 |
| Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for the Treatment of Cold Sores ethanol/glycolic acid solution, Placebo/Ethanol - Recurrent Herpes Labialis | Phase 2 | Completed | Topical Remedy | 469 | 2013-11-01 | 2015-07-16 |
| Evaluation of Cold Sore Treatments on Ultra Violet (UV) Induced Cold Sores Matching Placebo, BTL-TML-HSV - Oral Herpes Simplex | Phase 2 | Completed | Beech Tree Labs, Inc. | 303 | 2013-07-01 | 2016-04-28 |
| Safety and Efficacy Study of a New Treatment for Recurrent Symptoms of Oral Herpes Virus Infection BTL TML HSV, Matching placebo - Oral Herpes Simplex | Phase 1 / Phase 2 | Completed | Beech Tree Labs, Inc. | 171 | 2011-01-01 | 2013-08-13 |
| Place Controlled Study to Treat Recurrent Herpes Labialis. Ointment - Recurrent Herpes Labialis | Phase 2 | Completed | University of Zurich | 40 | 2009-04-01 | 2011-08-08 |
| Safety and Pharmacokinetics of Famciclovir Single 1500 mg Dose in Adolescents With Recurrent Herpes Labialis Famciclovir - Herpes Labialis | Phase 2 / Phase 3 | Completed | Novartis Pharmaceuticals | 53 | 2009-03-25 | 2021-06-25 |
| Iontophoretic Application of Acyclovir Gel to Treat Cold Sores Iontophoretic delivery of acyclovir - Herpes Labialis | Phase 2 | Completed | Transport Pharmaceuticals | 810 | 2007-04-01 | 2008-02-04 |
| Safety, Pharmacokinetics, and Efficacy Study of NB-001 to Treat Recurrent Herpes Labialis NB-001 - Herpes Labialis | Phase 2 | Completed | NanoBio Corporation | 1000 | 2007-02-01 | 2008-05-30 |
| Iontophoretic Application of Acyclovir Cream to Treat Recurrent Herpes Labialis iontophoretic acyclovir - Herpes Labialis | Phase 2 | Completed | Transport Pharmaceuticals | 1800 | 2005-04-01 | 2006-07-04 |
| Valacyclovir+Temovate Gel for the Treatment of Herpes Labialis valacyclovir+clobetasol gel - Herpes Labialis | Phase 2 | Completed | University of Utah | 300 | 2004-09-01 | 2008-05-06 |
| Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better? Orthognathic surgery, Distraction osteogenesis - Cleft Lip and Palate, Maxillary Hypoplasia | Phase 2 | Completed | The University of Hong Kong | 60 | 2002-06-01 | 2011-09-13 |
| Efficacy of Acyclovir in Combination With a Glucocorticosteroid on UV-Induced Herpes Labialis ME-609, Vehicle - Herpes Labialis | Phase 2 | Completed | Medivir | 417 | 1999-08-01 | 2008-08-15 |
Showing 20 of 21. Sign in to see all of them.
Herpes Labialis (15) · Cleft Lip (4) · Cleft Palate (3) · Herpes Simplex (3) · Head and Neck Neoplasms (2) · Lip Neoplasms (2) · Mouth Neoplasms (2) · Stomatitis, Herpetic (2) · Alveolar Bone Loss (1) · Bile Duct Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Mucoepidermoid (1) · Carcinoma, Renal Cell (1) · Carcinoma, Squamous Cell (1) · Cholangiocarcinoma (1)
Mouth Diseases (21) · Stomatognathic Diseases (21) · Skin Diseases (16) · Skin and Connective Tissue Diseases (16) · DNA Virus Infections (15) · Herpesviridae Infections (15) · Infections (15) · Skin Diseases, Infectious (15) · Skin Diseases, Viral (15) · Virus Diseases (15) · Herpes Simplex (12) · Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Craniofacial Abnormalities (4)
Ethanol (2) · Neurofibromin 2 (2) · 5-((2-(6-Amino-9H-purin-9-yl) ethyl) amino)-1-pentanol (1) · Acyclovir (1) · Botulinum Toxins, Type A (1) · Cetuximab (1) · Famciclovir (1) · ME 609 (1) · Ointments (1) · Orthognathic Surgery (1) · Osteogenesis, Distraction (1) · Saline Solution (1) · ficlatuzumab (1) · pritelivir (1) · squaric acid dibutyl ester (1)
Beech Tree Labs, Inc. (2) · Topical Remedy (2) · Transport Pharmaceuticals (2) · AiCuris Anti-infective Cures AG (1) · Hospital Sirio-Libanes (1) · Klus Pharma Inc. (1) · Medivir (1) · NanoBio Corporation (1) · Novartis Pharmaceuticals (1) · Shulov Innovate for Science Ltd. 2012 (1) · Squarex, LLC (1) · The University of Hong Kong (1) · The University of Texas Health Science Center, Houston (1) · University of Arizona (1) · University of Florida (1)
United States (15) · Brazil (2) · Hong Kong (1) · Israel (1) · Switzerland (1) · Taiwan (1)
Alicia Bucko, DO (1) · Brian Bock, DO (1) · Christopher Hull, MD (1) · Christopher M Hull, MD (1) · Cynthia B Strout, MD (1) · Daniel H Brune, MD (1) · Daniel Stewart, MD (1) · David Fried, MD (1) · Dennis Riff, MD (1) · Douglass Forsha, MD (1) · Edward Pornoy, MD (1) · Elias Kolettis, MD (1) · Eric M Morrel, PhD (1) · Eugene Monroe, MD (1)
PMID 35142535, PMID 19143902, PMID 21178655, PMID 36977289
P30CA023074 (1), R01DE010437 (1)