16 completed, 2 recruiting, 2 unknown, 1 not yet recruiting. 8 Phase 3, 5 Phase 4, 4 Not applicable, 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 7, Terminated 1 |
| Phase 4 | 5 | Completed 4, Recruiting 1 |
| Not applicable | 4 | Completed 2, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 1 | 2 | Completed 2 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Brivudine in the Treatment of Herpes Zoster Brivudine, Famciclovir - Herpes Zoster | Phase 4 | Recruiting | Peking University Third Hospital | 140 | 2025-08-25 | 2026-01-02 |
| Multimodal Nerve Block and Pulse Radiofrequency for Acute Herpes Zoster Pain Ultrasound-Guided Pulsed Radiofrequency (PRF), Intercostal nerve block (2% ropivacaine or 133 mg of liposomal bupivacaine), Paravertebral (PVB) Block (2% ropivacaine or 133 mg of liposomal bupivacaine) - Herpes Zoster (HZ) | Not applicable | Not yet recruiting | Xiaguang Duan | 120 | 2025-02-01 | 2025-01-29 |
| Effect of Mechanical Ventilation on Radiofrequency Ablation in Atrial Fibrillation Radiofrequency Ablation with FCV., Radiofrequency Ablation with VCV. - Radiofrequency Ablation, Atrial Fibrillation | Recruiting | Kocaeli City Hospital | 50 | 2025-01-01 | 2025-01-24 | |
| Famciclovir in Multiple Sclerosis Famciclovir - Multiple Sclerosis | Phase 2 | Unknown | Queen Mary University of London | 30 | 2020-11-25 | 2022-03-17 |
| Effect of Early Use of Oxycodone During the Acute Phase of Herpes Zoster on Preventing Postherpetic Neuralgia Oxycodone, Gabapentin, Famciclovir - Herpes Zoster, Post-herpetic Neuralgia | Not applicable | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 140 | 2017-05-01 | 2017-04-19 |
| Efficacy of Oral Famciclovir 125mg Comparing to Aciclovir 200 mg Treatment in Patients With Active Recurrent Genital Herpes Famciclovir, Aciclovir - GENITAL HERPES | Phase 3 | Completed | EMS | 150 | 2012-07-01 | 2021-04-21 |
| Efficacy of Oral Famciclovir Versus Aciclovir Treatment in Patients With Herpes Zoster Famciclovir, Aciclovir - Herpes Zoster | Phase 3 | Completed | EMS | 177 | 2012-06-01 | 2019-04-17 |
| Famvir for Treatment of Hearing in Unilateral Meniere's Disease Famciclovir, Placebo - Meniere's Disease | Phase 3 | Terminated | House Research Institute | 11 | 2011-12-01 | 2021-04-19 |
| Safety and Pharmacokinetics of Famciclovir Single 1500 mg Dose in Adolescents With Recurrent Herpes Labialis Famciclovir - Herpes Labialis | Phase 2 / Phase 3 | Completed | Novartis Pharmaceuticals | 53 | 2009-03-25 | 2021-06-25 |
| Pharmacokinetics, Acceptability and Safety of Famciclovir in Infants (1 Month to Less Than 12 Months) With Herpes Simplex Infection famciclovir - Herpes Simplex | Phase 2 | Completed | Novartis | 18 | 2007-10-01 | 2011-02-11 |
| Bioequivalency Study of Famciclovir 500 mg Tablets Under Fasted Conditions famciclovir - Herpes | Not applicable | Completed | Roxane Laboratories | 36 | 2007-07-01 | 2018-01-23 |
| Bioequivalency Study of Famciclovir 500 mg Tablets Under Fed Conditions famciclovir - Herpes | Not applicable | Completed | Roxane Laboratories | 31 | 2007-07-01 | 2018-01-23 |
| Patient-initiated Episodic Treatment of Recurrent Genital Herpes in Black Patients Famciclovir, Placebo - Genital Herpes | Phase 4 | Completed | Novartis | 463 | 2007-06-01 | 2011-03-28 |
| Efficacy and Safety of Famciclovir 1-day Treatment Compared to 3-day Treatment With Valacyclovir in Adults With Recurrent Genital Herpes Famciclovir, Valacyclovir, Placebo matching famciclovir - Genital Herpes | Phase 3 | Completed | Novartis Pharmaceuticals | 1179 | 2006-03-01 | 2011-06-30 |
| Famciclovir Oral Pediatric Formulation in Children 1-12 Years of Age With Varicella Zoster Infection famciclovir - Chickenpox, Herpes Zoster | Phase 3 | Completed | Novartis | 76 | 2005-07-01 | 2007-09-26 |
| Famciclovir Pediatric Formulation in Children 1 to 12 Years of Age With Herpes Simplex Infection Famciclovir - Herpes Simplex | Phase 3 | Completed | Novartis Pharmaceuticals | 74 | 2005-02-01 | 2013-04-25 |
| Famciclovir 500 mg Tablets Under Non-Fasting Conditions Famciclovir 500 mg Tablets, Famvir® 500 mg Tablets - Healthy | Phase 1 | Completed | Teva Pharmaceuticals USA | 36 | 2004-08-01 | 2024-08-20 |
| Famciclovir 500 mg Tablets Under Fasting Conditions Famciclovir 500 mg Tablets, Famvir® 500 mg Tablets - Healthy | Phase 1 | Completed | Teva Pharmaceuticals USA | 36 | 2004-08-01 | 2024-08-20 |
| A Study to Evaluate the Effect of Famciclovir in Reducing Herpes Virus Shedding Famciclovir - Genital Herpes | Phase 4 | Completed | Novartis | 2004-07-01 | 2012-04-27 | |
| A Study to Evaluate the Safety and Efficacy of Single Day or Single Dose Famciclovir for the Treatment of Recurrent Herpes Labialis Famciclovir - Recurrent Herpes Labialis | Phase 4 | Completed | Novartis | 2003-10-01 | 2007-12-10 |
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Herpes Simplex (7) · Herpes Genitalis (6) · Herpes Zoster (5) · Herpes Labialis (3) · Atrial Fibrillation (1) · Chickenpox (1) · Hearing Loss (1) · Meniere Disease (1) · Multiple Sclerosis (1) · Neuralgia, Postherpetic (1) · Pain (1) · Pathologic Complete Response (1) · Tinnitus (1) · Vertigo (1)
Novartis (7) · Novartis Pharmaceuticals (3) · EMS (2) · Roxane Laboratories (2) · Teva Pharmaceuticals USA (2) · House Research Institute (1) · Kocaeli City Hospital (1) · Peking University Third Hospital (1) · Queen Mary University of London (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Xiaguang Duan (1)
United States (12) · Canada (3) · Australia (2) · Brazil (2) · China (2) · Panama (2) · Costa Rica (1) · Germany (1) · Guatemala (1) · South Africa (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Irwin Plisco, M.D. (2) · Benno G Roesch, M.D. (1) · Dalu Mohammed, Dr (1) · Dr. Jeffery L. Blumer (1) · Jennifer Derebery, MD (1) · Joyce Silva, MD (1) · Roberto Amazonas, MD (1)
PMID 19273678, PMID 18621575, PMID 19192993, PMID 19195785, PMID 20070143, PMID 20160046, PMID 21178655, PMID 29746903, PMID 38131621