129 completed, 20 terminated, 18 unknown, 16 recruiting. 63 Phase 2, 41 Phase 3, 25 Not applicable, 25 Phase 1, 10 Phase 4.
Follow Leishmaniasis: new trials by email Literature Review of Leishmaniasis trials Research Report on Leishmaniasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL) Sodium Stibogluconate (SSG), Miltefosine, Miltefosine + Paromomycin - Cutaneous Leihmaniasis | Phase 3 | Not yet recruiting | Institute of Tropical Medicine, Belgium | 900 | 2027-01-01 | 2026-03-10 |
| Immersive Technology Headsets to Reduce Procedural Pain and Anxiety: Feasibility and Effects in Cutaneous Leishmaniasis Patients in Pakistan Virtual Reality - Cutaneous Leishmaniasis, Pain | Not applicable | Not yet recruiting | Stanford University | 15 | 2027-01-01 | 2026-10-05 |
| Ex Vivo Immunogenicity Screening of Vaccine Candidate Antigen Combinations in Ethiopian Patients With Leishmaniasis Leishmaniasis, Cutaneous, Leishmaniasis | Recruiting | Institute of Tropical Medicine, Belgium | 90 | 2026-05-26 | 2026-08-24 | |
| Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers A mobile app with AI functionality for diagnosing skin-related NTDs - Skin and Connective Tissue Diseases, Neglected Tropical Diseases | Not applicable | Not yet recruiting | Kenya Medical Research Institute | 2420 | 2026-05-01 | 2026-04-02 |
| Arnica Tincture Fot the Treatment of Cutaneous Leishmaniasis II. Arnica Tincture, Meglumine antimoniate. - Leishmaniasis, Cutaneous | Phase 3 | Recruiting | Universidad de Antioquia | 96 | 2026-03-11 | 2026-04-02 |
| Pilot Study: Miltefosine Gel (G-MTF) in Patients With Cutaneous Leishmaniasis MILTEFOSINE gel - Cutaneous Leishmaniasis, Cutaneous Leishmaniasis, American | Phase 1 | Not yet recruiting | Universidad Industrial de Santander | 15 | 2026-01-01 | 2025-09-08 |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Recurrent Visceral Leishmaniasis in HIV Co-Infection Hiv, Visceral Leishmaniasis | Recruiting | Institute of Tropical Medicine, Belgium | 20 | 2025-10-21 | 2026-03-23 | |
| Human Bioequivalence Study of Liposomal Amphotericin B for Injection Test product (Liposomal amphotericin B for injection, Sichuan Huiyu Pharmaceutical Co., Ltd.), Reference product (AmBisome®, Astellas Pharma US Inc.) - Invasive Fungal Infections, Neutropenic Fever | Not applicable | Completed | Sichuan Huiyu Pharmaceutical Co., Ltd | 58 | 2025-05-25 | 2026-05-27 |
| Human Bioequivalence Study of Amphotericin B Liposome for Injection Amphotericin B Liposome for Injection (strength: 50 mg, Sichuan Huiyu Pharmaceutical Co., Ltd.), Amphotericin B Liposome for Injection (trade name: Ambisome®, strength: 50 mg, MAH: Gilead Sciences) - Invasive Fungal Infections, Neutropenic Fever | Not applicable | Completed | Sichuan Huiyu Pharmaceutical Co., Ltd | 42 | 2025-05-13 | 2026-05-22 |
| Feasibility of Integrating Thermotherapy for Treatment of Cutaneous Leishmaniasis in Primary Health Care Setup Thermotherapy - Cutaneous Leishmaniasis | Not applicable | Recruiting | Armauer Hansen Research Institute, Ethiopia | 103 | 2025-04-24 | 2026-10-16 |
| Antimicrobial Adjuvants to Revert the Imbalance of Skin Microbiota for Improved Outcomes of Complicated Cutaneous Leishmaniasis Treatment in Ethiopia Fusidic Acid, Vehicle cream - Leishmaniasis, Cutaneous | Phase 3 | Not yet recruiting | Institute of Tropical Medicine, Belgium | 180 | 2025-04-01 | 2024-11-19 |
| Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne Diseases Peripheral venous blood sample - Leishmaniasis, Leptospirosis | Not applicable | Not yet recruiting | University Hospital, Montpellier | 183 | 2025-03-03 | 2025-03-05 |
| Intralesional Injection of Metronidazole for the Management of Cutaneous Leishmaniasis Metronidazole - Cutaneous Leishmaniasis | Phase 2 | Recruiting | Hayder Adnan Fawzi | 40 | 2025-02-10 | 2025-02-14 |
| Intralesional Injection of Levofloxacin for the Management of Cutaneous Leishmaniasis Levofloxacin 0.5% - Cutaneous Leishmaniasis | Phase 2 | Recruiting | Hayder Adnan Fawzi | 40 | 2025-02-09 | 2025-09-30 |
| Ciprofloxacin Intralesional Injection for the Treatment of Cutaneous Leishmaniasis Compared to Sodium Stibogluconate Ciprofloxacin (BAYO9867), sodium stibogluconate (Pentostam) - Cutaneous Leishmaniasis | Phase 2 | Recruiting | Al-Mustafa University College | 80 | 2025-02-07 | 2025-09-30 |
| Treatment of Bolivian L Braziliensis Mucosal Leishmaniasis With Inhaled Pentamidine Plus Oral Miltefosine Miltefosine Oral Capsule - Mucosal Leishmaniasis | Phase 2 | Recruiting | Fundacion Nacional de Dermatologia | 30 | 2025-02-04 | 2025-02-26 |
| LEISH-PED: Study on Leishmaniasis in Children Leishmania Infantum Disease, Leishmaniasis, Visceral | Recruiting | Meyer Children's Hospital IRCCS | 200 | 2025-01-30 | 2026-04-01 | |
| OPTImizing MIltefosine Treatment for Cutaneous LEISHmaniasis Patients Miltefosine - Cutaneous Leishmaniases | Recruiting | Institute of Tropical Medicine, Belgium | 80 | 2024-06-18 | 2024-07-23 | |
| Leishmania Antigen Rapid Diagnostic Test Proof-of-Concept and Validation Study Antigen detection Rapid Diagnostic Test prototype - Visceral Leishmaniasis | Terminated | Foundation for Innovative New Diagnostics, Switzerland | 72 | 2023-12-20 | 2025-01-28 |
Showing 20 of 199. Sign in to see all of them.
Leishmaniasis, Cutaneous (102) · Leishmaniasis, Visceral (61) · Leishmaniasis, Mucocutaneous (21) · Hyperthermia (5) · Brucellosis (4) · Neglected Diseases (4) · Chikungunya Fever (3) · Disease (3) · Leptospirosis (3) · Malaria (3) · Skin Diseases, Parasitic (3) · Vector Borne Diseases (3) · Zika Virus Infection (3) · Acquired Immunodeficiency Syndrome (2)
Euglenozoa Infections (199) · Infections (199) · Protozoan Infections (199) · Parasitic Diseases (197) · Vector Borne Diseases (196) · Skin Diseases, Infectious (149) · Skin and Connective Tissue Diseases (148) · Skin Diseases (147) · Skin Diseases, Parasitic (146) · Pathological Conditions, Signs and Symptoms (18) · Pathologic Processes (12) · Leishmaniasis, Cutaneous (11) · Bacterial Infections and Mycoses (8) · Disease Attributes (7)
miltefosine (39) · Meglumine Antimoniate (25) · Paromomycin (19) · liposomal amphotericin B (19) · Antimony Sodium Gluconate (14) · Amphotericin B (7) · amphotericin B, deoxycholate drug combination (5) · Pentamidine (4) · Pentoxifylline (4) · Allopurinol (3) · Hyperthermia, Induced (3) · Antimony (2) · Arnicae flos extract (2) · Cryotherapy (2) · Data Collection (2)
U.S. Army Medical Research and Development Command (16) · Drugs for Neglected Diseases (14) · Institute of Tropical Medicine, Belgium (14) · Hospital Universitário Professor Edgard Santos (10) · Access to Advanced Health Institute (AAHI) (8) · Banaras Hindu University (8) · National Institute of Allergy and Infectious Diseases (NIAID) (8) · International Centre for Diarrhoeal Disease Research, Bangladesh (6) · University of Brasilia (6) · Centro Internacional de Entrenamiento e Investigaciones Médicas (5) · Foundation for Innovative New Diagnostics, Switzerland (5) · Fundacion Nacional de Dermatologia (5) · Knight Therapeutics (USA) Inc (5) · University of York (5) · AB Foundation (4)
Brazil (25) · Ethiopia (22) · United States (21) · India (19) · Colombia (17) · Bolivia (14) · Bangladesh (9) · Kenya (9) · Sudan (8) · Peru (7) · Tunisia (6) · France (5) · United Kingdom (5) · Israel (4) · Pakistan (4)
Shyam Sundar, MD (9) · Jaime Soto, MD (4) · Afif Ben Salah, M.D., Ph.D. (3) · Paulo RL Machado, MD, PhD (3) · Alejandro Llanos-Cuentas, MD, PhD (2) · Armando O. Schubach, MD, PhD (2) · Charles Lacey, BMBS, MD (2) · Edgar M Carvalho, MD, PhD (2) · Ermias Diro, MD (2) · Franco M Piazza, MD, MPH (2) · Franco M Piazza, MD, MPh (2) · Franco Piazza, MD, MPH (2) · Israel Cruz, PhD (2)
PMID 28379954, PMID 23877689, PMID 34053461, PMID 11353640, PMID 17582067, PMID 17682988, PMID 18781879, PMID 19415122, PMID 19636365, PMID 19663597, PMID 19959405, PMID 20016847, PMID 20126269, PMID 20147716, PMID 20231896, PMID 20438389, PMID 20851080, PMID 21049063, PMID 21129762, PMID 21200420, PMID 21255828, PMID 21375777, PMID 21460008, PMID 21633025, PMID 21718522, PMID 22238470, PMID 22594858, PMID 22665599, PMID 22724029, PMID 23029576, PMID 23388004, PMID 23390069, PMID 23740007, PMID 24454970, PMID 24743328, PMID 25233346, PMID 26203904, PMID 26496648, PMID 26573827, PMID 27188804, PMID 27627654, PMID 27803094, PMID 27812090, PMID 27927991, PMID 27956421, PMID 28327804, PMID 28558061, PMID 28558062, PMID 28662034, PMID 29020217
U19AI065866 (3), 2016 (1), 2018 (1), 2019 (1)