4 completed, 2 unknown, 1 terminated. 7 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 4, Unknown 2, Terminated 1 |
Follow Left Ventricular Hypertrophy: new trials by email Literature Review of Left Ventricular Hypertrophy trials Research Report on Left Ventricular Hypertrophy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Angiotensin-converting-enzyme (ACE) Inhibitors in Hemodialysis ACE inhibitor Ramipril, non-RAS inhibitor antihypertensive therapy - Left Ventricular Hypertrophy, Hypertension | Phase 3 | Completed | Mario Negri Institute for Pharmacological Research | 269 | 2009-05-01 | 2021-01-11 |
| The PRIMO Study: Paricalcitol Capsules Benefits Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease Stage 3/4 paricalcitol, placebo - Chronic Kidney Disease, Left Ventricular Hypertrophy | Phase 3 | Completed | AbbVie (prior sponsor, Abbott) | 227 | 2008-02-01 | 2013-03-12 |
| Stenting of Renal Artery Stenosis in Coronary Artery Disease Study stenting angioplasty plus medical therapy, Medical therapy - Renal Artery Stenosis, Left Ventricular Hypertrophy | Phase 3 | Unknown | Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele | 168 | 2006-04-01 | 2010-08-02 |
| Effect of Angiotensin II Receptor Blockers (ARB) on Left Ventricular Reverse Remodelling After Aortic Valve Replacement in Severe Valvular Aortic Stenosis Candesartan - Aortic Valve Stenosis, Left Ventricular Hypertrophy | Phase 3 | Unknown | Odense University Hospital | 140 | 2006-02-01 | 2009-06-30 |
| Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential Hypertension Aliskiren 150/300 mg, Losartan 50/100 mg, Aliskiren placebo - Hypertension, Left Ventricular Hypertrophy | Phase 3 | Completed | Novartis Pharmaceuticals | 460 | 2005-10-01 | 2011-05-26 |
| Hypertension in Hemodialysis Patients (Aim 3) Lisinopril, Atenolol - Hemodialysis, Hypertension | Phase 3 | Terminated | Indiana University | 200 | 2005-08-01 | 2016-01-18 |
| A Safety and Efficacy Study for Epoetin Alfa in Pre-dialysis Subjects. epoetin alfa - Anemia, Kidney Failure | Phase 3 | Completed | Janssen-Ortho Inc., Canada | 172 | 1997-12-01 | 2011-02-01 |
Hypertrophy, Left Ventricular (7) · Hypertension (3) · Anemia (1) · Aortic Valve Stenosis (1) · Atrial Fibrillation (1) · Overweight (1) · Renal Artery Obstruction (1) · Renal Insufficiency (1) · Renal Insufficiency, Chronic (1)
Cardiomegaly (7) · Cardiovascular Diseases (7) · Heart Diseases (7) · Hypertrophy (7) · Pathological Conditions, Anatomical (7) · Pathological Conditions, Signs and Symptoms (7) · Vascular Diseases (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Kidney Diseases (3) · Male Urogenital Diseases (3) · Urogenital Diseases (3) · Urologic Diseases (3) · Pathologic Processes (2) · Aortic Valve Disease (1)
Atenolol (1) · Epoetin Alfa (1) · Lisinopril (1) · Losartan (1) · Nutrition Therapy (1) · aliskiren (1) · candesartan (1) · paricalcitol (1)
AbbVie (prior sponsor, Abbott) (1) · Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele (1) · Indiana University (1) · Janssen-Ortho Inc., Canada (1) · Mario Negri Institute for Pharmacological Research (1) · Novartis Pharmaceuticals (1) · Odense University Hospital (1)
Italy (4) · United States (3) · Germany (2) · Russia (2) · Spain (2) · Argentina (1) · Australia (1) · Colombia (1) · Czechia (1) · Denmark (1) · Finland (1) · Poland (1) · Puerto Rico (1) · Romania (1) · Sweden (1)
Ann Eldred, MD (1) · Carmelita Marcantoni, M.D. (1) · Henrik Nissen, MD, PhD (1) · Jacob E Moller, Md, Ph.D (1) · Jordi S Dahl, MD, MMSci (1) · Lars I Andersen, MD, DMSc (1) · Piero Ruggenenti, MD (1) · Rajiv Agarwal, MD (1) · Torben Haghfelt, Md, DMSc (1)
PMID 16253719, PMID 18591942, PMID 21242674, PMID 21353251, PMID 21746765, PMID 22337679, PMID 22495466, PMID 22869821, PMID 23194491, PMID 23316326, PMID 24173271, PMID 24398888, PMID 27085434, PMID 33782036, PMID 35224730, PMID 37651553, PMID 40013543, PMID 40665514
2008 (1), R01DK062030 (1)