20 completed, 13 unknown, 6 recruiting, 4 not yet recruiting. 19 Not applicable, 8 Phase 2, 6 Phase 3, 6 Phase 4.
Follow Laparotomy: new trials by email Literature Review of Laparotomy trials Research Report on Laparotomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SurgWeek-2: Identifying the Global Burden of Post Operative Complications: an International Prospective Cohort Study Protocol Surgery Complications, Surgery | Not yet recruiting | University of Birmingham | 100000 | 2026-08-31 | 2026-08-25 | |
| Saudi Emergency Laparotomy Audit Emergency Laparotomy - Laparotomy, Laparotomy Surgery | Not yet recruiting | King Faisal Specialist Hospital & Research Center | 10000 | 2026-06-01 | 2026-02-24 | |
| Clinical Outcomes of Non-Indicated Staged Laparotomies in Abdominal Trauma Laparotomy refers to a definitive single-stage exploratory abdominal surgery. Damage Control Surgery refers to a staged surgical approach including initial abbreviated laparotomy followed by planned. - Abdominal Trauma, Damage Control Surgery | Not yet recruiting | Far Eastern Memorial Hospital | 350 | 2025-08-15 | 2025-08-07 | |
| Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery Intrathecal Morphine, Epidural Analgesia - Colorectal Carcinoma, Analgesia, Postoperative | Phase 4 | Recruiting | Meri Mirceta | 98 | 2025-04-08 | 2025-04-20 |
| IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia Intravenous administered opioid, Epidural administered opioid - Laparotomy | Phase 2 / Phase 3 | Recruiting | University of Iowa | 80 | 2024-09-17 | 2026-04-28 |
| Evaluation of Performance-based Functional Outcome Measures After Open Abdominal Surgery Standardised Physiotherapy Plan - Laparotomy | Not applicable | Completed | Riphah International University | 50 | 2024-04-01 | 2024-08-14 |
| "Dexa vs Dexmedetomidine With Bupivacaine in TAP Block for Laparotomy Analgesia Bupivacaine Hcl 0.25% Inj_#1, Bupivacaine Hcl 0.25% Inj_#2 - Pain, Postoperative, Opioid Use | Phase 2 / Phase 3 | Recruiting | Sahiwal medical college sahiwal | 96 | 2024-03-03 | 2026-05-15 |
| Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture - Laparotomy, Dehiscence Wound | Not applicable | Not yet recruiting | University of Southern California | 250 | 2024-01-01 | 2023-11-28 |
| Early vs Postponed Parenteral Nutrition After Emergency Abdominal Surgery SmofKabiven - Laparotomy, Bowel Obstruction | Phase 4 | Active not recruiting | Copenhagen University Hospital at Herlev | 342 | 2023-10-18 | 2026-10-22 |
| DuraMesh Laparotomy Study Duramesh suturable mesh for laparotomy closure, Conventional suture for laparotomy closure - Laparotomy, Suture; Complications, Mechanical | Not applicable | Withdrawn | Mesh Suture Inc. | 2023-10-15 | 2022-09-13 | |
| M-TAPA vs RSB in Midline Abdominal Incision Laparotomy Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA), Rectus Sheath Block - Postoperative Pain, Laparotomy | Not applicable | Active not recruiting | Cumhuriyet University | 60 | 2023-06-01 | 2025-11-18 |
| S-TAP vs RSB in Midline Abdominal Incision Laparotomy Subcostal Transversus Abdominis Plane Block, Rectus Sheath Block - Postoperative Pain, Laparotomy | Not applicable | Active not recruiting | Cumhuriyet University | 60 | 2023-06-01 | 2025-11-18 |
| Clinical Performance and Safety of Suture-TOOL Suture-TOOL - Laparotomy, Incisional Hernia | Not applicable | Unknown | Suturion AB | 38 | 2023-01-10 | 2023-01-23 |
| PIB for Post-operative Analgesia After Laparotomy : Determining the Optimum Dose Programmed intermittent epidural bolus 5 ml, Programmed intermittent epidural bolus 6 ml, Programmed intermittent epidural bolus 7 ml - Acute Post Operative Pain, Laparotomy | Not applicable | Completed | Ciusss de L'Est de l'Île de Montréal | 60 | 2022-12-01 | 2026-10-13 |
| Abdominal Wall Closure After Laparotomy in Oncologic Surgery REBUILD Bioabsorbable - Laparotomy | Not applicable | Recruiting | AbSolutions Med Inc. | 30 | 2022-06-17 | 2022-12-27 |
| Influence of Analgesic Technique on Post Operative Rehabilitation After Median Laparotomy Epidural analgesia, Bilateral rectus sheath block, Laparotomy - Laparotomy | Not applicable | Recruiting | Centre Hospitalier Régional Metz-Thionville | 110 | 2021-10-11 | 2025-12-16 |
| Are Standard Dosing Regimens of Piperacillin-Tazobactam Suitable in Critically Ill Patients With Open Abdomen and Negative Pressure Wound Therapy? A Population Pharmacokinetic Study. Blood sampling (T0, inclusion), other samplings (T1) - Laparotomy, Critical Illness | Completed | University Hospital, Bordeaux | 46 | 2021-07-01 | 2023-02-27 | |
| Perioperative Respiratory Care and Outcomes for Patients Undergoing High Risk Abdominal Surgery Chlorhexidine mouthwash, Oxygen - Infection, Pneumonia | Phase 3 | Recruiting | University of Birmingham | 12942 | 2020-11-13 | 2025-02-19 |
| Comparison of CRP Levels, Neutrophil Count, and Clinical Outcomes of Low Dose Ketamine Between at Anesthesia Induction and at the End of Surgery in Patients Undergo Elective Laparotomy Ketamine 0.3 mg/kg at end-of-surgery, Ketamine 0.3 mg/kg at anesthesia induction - General Anesthesia, Laparotomy | Not applicable | Completed | Udayana University | 68 | 2020-07-27 | 2020-11-12 |
| TCI vs Manually Controlled Infusion of Propofol Target controlled infusion - Anesthesia, Intravenous, Laparotomy | Unknown | Regional Hospital West Jutland | 40 | 2020-05-01 | 2020-02-17 |
Showing 20 of 49. Sign in to see all of them.
Pain, Postoperative (7) · Gastrointestinal Diseases (3) · Abdomen, Acute (2) · Abdominal Injuries (2) · Agnosia (2) · Emergencies (2) · Ileus (2) · Incisional Hernia (2) · Intestinal Obstruction (2) · Intestinal Perforation (2) · Postoperative Complications (2) · Surgical Wound Infection (2) · Uterine Cervical Neoplasms (2) · Wound Infection (2) · Acute-Phase Reaction (1)
Pathological Conditions, Signs and Symptoms (24) · Pathologic Processes (19) · Postoperative Complications (11) · Neurologic Manifestations (10) · Signs and Symptoms (10) · Pain (9) · Digestive System Diseases (8) · Disease Attributes (5) · Infections (5) · Intestinal Diseases (5) · Wounds and Injuries (5) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Gastrointestinal Diseases (4) · Neoplasms (4)
Oxygen (4) · Analgesia, Epidural (2) · Laparotomy (2) · Blood Specimen Collection (1) · Bupivacaine (1) · Chemoradiotherapy (1) · Control Groups (1) · Dental Occlusion (1) · Dexmedetomidine (1) · Enhanced Recovery After Surgery (1) · Ischemic Preconditioning (1) · Ketamine (1) · Laparoscopy (1) · Nefopam (1) · Nitrous Oxide (1)
Lei Li (3) · Cumhuriyet University (2) · Jawaharlal Nehru Medical College (2) · University of Birmingham (2) · AbSolutions Med Inc. (1) · Aesculap AG (1) · Assistance Publique - Hôpitaux de Paris (1) · Case Comprehensive Cancer Center (1) · Centre Hospitalier Régional Metz-Thionville (1) · Christian Medical College and Hospital, Ludhiana, India (1) · Ciusss de L'Est de l'Île de Montréal (1) · Copenhagen University Hospital at Herlev (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dow University of Health Sciences (1) · Duke University (1)
United States (6) · China (4) · France (4) · Denmark (3) · Croatia (2) · India (2) · Pakistan (2) · Sweden (2) · Turkey (Türkiye) (2) · Belgium (1) · Brazil (1) · Canada (1) · Colombia (1) · Egypt (1) · Germany (1)
Kaushal D Singh, MS Surgery (2) · Abeer A Hassanien (1) · Adeel Riaz, MD (1) · Amanda Kumar, MD (1) · Baburao Koneru, MD, MPH (1) · Boris Mraovic, Prof, MD (1) · Chien Wu, MD (1) · Christian S Meyhoff, MD (1) · Christian S Meyhoff, MD, PhD (1) · Christian S. Meyhoff, MD, PhD (1) · Christopher Ryalino, Dr (1)
PMID 17707752, PMID 19826023, PMID 21136109, PMID 22647387, PMID 22840231, PMID 24860156, PMID 25384994, PMID 27358262, PMID 28112798, PMID 28988184, PMID 31188201, PMID 31362966, PMID 31549201, PMID 32502439, PMID 32723388, PMID 32819996, PMID 33317612, PMID 34380437, PMID 37221022, PMID 39845163, PMID 40255646