82 completed. 82 Phase 2, 13 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 82 | Completed 82 |
| Phase 1 | 13 | Completed 13 |
| Phase 3 | 3 | Completed 3 |
Follow Keratosis: new trials by email Literature Review of Keratosis trials Research Report on Keratosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses Topical Aminolevulinate, Photodynamic therapy (PDT), Red light illumination - Actinic Keratoses | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2024-08-25 | 2026-02-20 |
| Comparison of Rimegepant and Placebo for Pain in IBS Rimegepant 75 MG [Nurtec] - Irritable Bowel Syndrome | Phase 2 | Completed | Mayo Clinic | 39 | 2024-06-06 | 2026-10-15 |
| Study on the Safety and Efficacy of Bimiralisib Gel in Participants Suffering From Actinic Keratosis Bimiralisib - Actinic Keratosis | Phase 2 | Completed | TORQUR | 46 | 2024-04-02 | 2025-07-18 |
| A 44-week Monocentric Open Study Assessing the Efficacy and Safety of Deucravacitinib in Adults With Inflammatory Genodermatoses deucravacitinib - Epidermolysis Bullosa Simplex, Ichthyosis | Phase 2 | Completed | Centre Hospitalier Universitaire de Nice | 8 | 2024-03-18 | 2026-10-16 |
| Short Contact Protocols to Reduce Pain During 10% ALA Gel Red-light Photodynamic Therapy of Actinic Keratoses Topical aminolevulinate (10% ALA gel), Red light illumination - Actinic Keratosis | Phase 2 | Completed | Case Comprehensive Cancer Center | 30 | 2023-10-02 | 2025-10-23 |
| ADX-629 Therapy for Sjogren-Larsson Syndrome ADX-629 - Sjogren-Larsson Syndrome | Phase 1 / Phase 2 | Completed | University of Nebraska | 8 | 2023-01-02 | 2026-05-05 |
| A Study to Evaluate Topically Applied SXR1096 Cream in Patients With Netherton Syndrome SXR1096 cream, Placebo cream - Netherton Syndrome | Phase 1 / Phase 2 | Completed | Sixera Pharma | 9 | 2021-12-07 | 2025-12-16 |
| Vitamin D Supplementation as a Neoadjuvant for Photodynamic Therapy of Actinic Keratoses Photodynamic therapy (PDT), Vitamin D3 - Actinic Keratosis | Phase 2 | Completed | Case Comprehensive Cancer Center | 75 | 2020-01-13 | 2022-06-24 |
| A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital Ichthyosis Isotretinoin, Vehicle - Congenital Ichthyosis | Phase 2 | Completed | LEO Pharma | 34 | 2019-12-03 | 2026-05-22 |
| 5-ALA Patch-PDT of Actinic Keratosis on the Upper Extremities PD P 506 A - Actinic Keratoses | Phase 2 | Completed | photonamic GmbH & Co. KG | 22 | 2018-07-12 | 2019-08-28 |
| Study to Evaluate the Efficacy, Safety, and Tolerability of Topical VDA-1102 Ointment in Subjects With Actinic Keratosis 10% VDA-1102, 20% VDA-1102 - Actinic Keratosis | Phase 2 | Completed | Vidac Pharma | 83 | 2018-05-23 | 2022-08-23 |
| DUSA: Cyclic PDT for the Prevention of AK & NMSC in Solid Organ Transplant Recipients Levulan® Kerastick®, BLU-U Blue Light Photodynamic Therapy - Skin Cancer, Non-melanoma Skin Cancer | Phase 1 / Phase 2 | Completed | Medical Dermatology Specialists | 8 | 2017-08-29 | 2024-03-15 |
| Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis AM001 Cream, 7.5%, Vehicle Cream - Actinic Keratosis | Phase 2 | Completed | AmDerma | 30 | 2017-06-06 | 2019-04-30 |
| Treatment of Plantar Keratosis With Medicinal Plant in Diabetic Patients Medicinal Plant, Salicylate, Vaseline - Keratosis Plantaris | Phase 2 | Completed | Universidade do Vale do Sapucai | 90 | 2017-06-01 | 2020-11-05 |
| Study of SOR007 Ointment for Actinic Keratosis SOR007 (Uncoated Nanoparticulate Paclitaxel) Ointment, SOR007 Ointment Vehicle - Actinic Keratosis | Phase 2 | Completed | DFB Soria, LLC | 33 | 2017-05-18 | 2019-05-15 |
| A Randomized, Vehicle-Controlled Study of 2 Concentrations of A-101 for the Treatment of Seborrheic Keratosis A-101 - Seborrheic Keratosis | Phase 2 | Completed | Aclaris Therapeutics, Inc. | 253 | 2017-05-17 | 2019-05-06 |
| A Six Week Topical Cream Study for Subjects With Ichthyosis Vulgaris 146-9251 cream, Vehicle cream - Ichthyosis Vulgaris | Phase 2 | Completed | Crown Laboratories, Inc. | 80 | 2017-04-25 | 2021-08-10 |
| A Safety and Tolerability Study of Topical PAT-001 in Congenital Ichthyosis PAT-001, 0.1%, PAT-001, 0.2%, Vehicle for PAT-001 0.1% - Congenital Ichthyosis | Phase 2 | Completed | Patagonia Pharmaceuticals, LLC | 19 | 2017-03-08 | 2021-09-29 |
| A Study to Evaluate Two Concentrations of DFD-07 Cream, in Subjects With Actinic Keratosis (AK) of the Face and/or Scalp Over a 12-week Treatment Period Low dose DFD07 once daily, High dose DFD07 once daily, High dose DFD07 twice daily - Actinic Keratosis (AK) | Phase 2 / Phase 3 | Completed | Dr. Reddy's Laboratories Limited | 240 | 2017-02-14 | 2019-04-24 |
| Perimenstrual Acne With Clindamycin Phosphate and Benzoyl Peroxide lidamycin phosphate and benzoyl peroxide 1.2%/3.75% combination - Actinic Keratosis | Phase 2 | Completed | Icahn School of Medicine at Mount Sinai | 22 | 2017-01-01 | 2020-09-04 |
Showing 20 of 82. Sign in to see all of them.
Keratosis, Actinic (59) · Keratosis, Seborrheic (5) · Carcinoma, Basal Cell (4) · Ichthyosis (4) · Ichthyosis Bullosa of Siemens (4) · Netherton Syndrome (4) · Precancerous Conditions (4) · Ichthyosis Vulgaris (3) · Irritable Bowel Syndrome (3) · Melanosis (3) · Constipation (2) · Ichthyosis, Lamellar (2) · Sjogren-Larsson Syndrome (2) · Skin Neoplasms (2)
Skin Diseases (82) · Skin and Connective Tissue Diseases (82) · Neoplasms (60) · Precancerous Conditions (55) · Congenital Abnormalities (16) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (16) · Genetic Diseases, Inborn (16) · Skin Abnormalities (16) · Skin Diseases, Genetic (15) · Infant, Newborn, Diseases (13) · Ichthyosis (12) · Neoplasms by Histologic Type (7) · Carcinoma (6) · Neoplasms, Glandular and Epithelial (6)
Aminolevulinic Acid (10) · 3-ingenyl angelate (9) · Photochemotherapy (5) · Imiquimod (4) · N-phenylacetoaminomethylene-DL-p-nitrophenylalanine (4) · Gels (3) · LEO 43204 (3) · Solutions (3) · Cryotherapy (2) · Isotretinoin (2) · Petrolatum (2) · SR-T100 (2) · 1-phenyl-3,3-dimethyltriazene (1) · 5-aminolevulinic acid hexyl ester (1) · ADX-629 (1)
LEO Pharma (8) · Peplin (8) · DUSA Pharmaceuticals, Inc. (6) · Aclaris Therapeutics, Inc. (4) · Almirall, S.A. (3) · Case Comprehensive Cancer Center (3) · Mayo Clinic (3) · Bispebjerg Hospital (2) · G&E Herbal Biotechnology Co., LTD (2) · Icahn School of Medicine at Mount Sinai (2) · Promius Pharma, LLC (2) · University of Arizona (2) · Vidac Pharma (2) · Aldeyra Therapeutics, Inc. (1) · AmDerma (1)
United States (52) · Germany (11) · Australia (6) · Canada (4) · France (4) · Austria (2) · Brazil (2) · Denmark (2) · Italy (2) · Sweden (2) · Switzerland (2) · Bangladesh (1) · Belgium (1) · Dominican Republic (1) · Finland (1)
Stuart Marcus, MD, PhD (6) · Gary Goldenberg, MD (2) · Janet Dubois, MD (2) · Albert C Yan, MD (1) · Amy Paller, MD (1) · Andrew Blauvelt, MD, MBA (1) · Anjali Shroff, MD (1) · Arthur P Bertolino, MD (1) · Brian Beger, BS (1) · C. William Hanke, MD (1) · Chaim M Brickman, MD (1) · Christine Bodemer, MD, PhD (1) · Christine Chiaverini (1) · Christoph Willers, MD, MBA (1) · Claus Garbe, Prof. Dr. (1)
PMID 38125671, PMID 11493098, PMID 20083693, PMID 20691689, PMID 22517769, PMID 22934545, PMID 24068130, PMID 24102348, PMID 25124939, PMID 25257941, PMID 25584134, PMID 26011755, PMID 26054651, PMID 28264612, PMID 29399258, PMID 29399263, PMID 33196758, PMID 35218370, PMID 35314199, PMID 37170057, PMID 40581198, PMID 41637861
P01CA027502 (2), UL1RR024150 (2), 1RC1DK086182 (1), 2014 (1), 2015 (1), P30CA023074 (1), R01DK054681 (1), R01DK079866 (1), R44CA250727 (1)