7 completed, 4 unknown, 1 enrolling by invitation. 4 Not applicable, 3 Phase 2, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 3, Unknown 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 4 | 2 | Enrolling by invitation 1, Unknown 1 |
Follow Ichthyosis Vulgaris: new trials by email Literature Review of Ichthyosis Vulgaris trials Research Report on Ichthyosis Vulgaris
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns Intact fish skin graft, autograft - Partial-thickness Burn Wounds | Phase 4 | Enrolling by invitation | Kerecis Ltd. | 65 | 2026-01-01 | 2026-01-08 |
| Exploring Patient Reported Outcomes in Inherited Ichthyosis Questionnaires with patient reported outcome measures - Congenital Ichthyosis | Unknown | Maastricht University Medical Center | 20 | 2023-09-01 | 2023-11-08 | |
| Quality of Life in Middle-aged and Older Patients With Congenital Ichthyosis Qualitative interview - Congenital Ichthyosis | Completed | Maastricht University Medical Center | 20 | 2022-11-14 | 2025-10-01 | |
| The Role Of Neutrophil Proteases As Global Regulators Of Il-1 Family Cytokine Activity In Skin Disorders No intervention - Psoriasis Vulgaris, Atopic Dermatitis | Unknown | St. James's Hospital, Ireland | 80 | 2021-03-02 | 2021-03-05 | |
| Scientific Substantiation and Assessment of the Effectiveness of Pathogenetic Methods of Therapy for Congenital Ichthyosis in Children Secukinumab Injection, Ustekinumab Injection, Dupilumab Injection - Congenital Ichthyosis | Phase 4 | Unknown | National Medical Research Center for Children's Health, Russian Federation | 50 | 2021-03-01 | 2021-08-09 |
| Kerecis Omega3 Wound Plus SOC vs. SOC Alone in Treating Severe Diabetic Foot Ulcers and Forefoot Amputations Kerecis™ Omega3 Wound, Standard of care - Diabetic Foot Ulcer, Dehiscence of Amputation Stump | Not applicable | Completed | Kerecis Ltd. | 260 | 2020-07-09 | 2023-02-06 |
| A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital Ichthyosis Isotretinoin, Vehicle - Congenital Ichthyosis | Phase 2 | Completed | LEO Pharma | 34 | 2019-12-03 | 2026-05-22 |
| Comparison of Different Concentrations of Carbamide as Moisturizers in Ichthyosis Vulgaris 7.5 % - Ichthyosis Vulgaris | Not applicable | Unknown | University of Aarhus | 20 | 2019-11-01 | 2019-11-01 |
| Fish Skin Compared to Cadaver Skin as Temporary Cover for Full Thickness Burns Fish skin, Cadaver skin - Burns | Not applicable | Completed | Kerecis Ltd. | 5 | 2019-02-14 | 2022-07-06 |
| A Six Week Topical Cream Study for Subjects With Ichthyosis Vulgaris 146-9251 cream, Vehicle cream - Ichthyosis Vulgaris | Phase 2 | Completed | Crown Laboratories, Inc. | 80 | 2017-04-25 | 2021-08-10 |
| A Safety and Tolerability Study of Topical PAT-001 in Congenital Ichthyosis PAT-001, 0.1%, PAT-001, 0.2%, Vehicle for PAT-001 0.1% - Congenital Ichthyosis | Phase 2 | Completed | Patagonia Pharmaceuticals, LLC | 19 | 2017-03-08 | 2021-09-29 |
| Genetic Screening for Filaggrin Mutation in Atopic Dermatitis and Ichthyosis Vulgaris in the African American Population Buccal Swab - Atopic Dermatitis, Ichthyosis Vulgaris | Not applicable | Completed | Northwestern University | 35 | 2010-06-01 | 2015-05-01 |
Burns (2) · Dermatitis, Atopic (2) · Diabetic Foot (1) · Eczema (1) · Netherton Syndrome (1)
Congenital Abnormalities (12) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (12) · Genetic Diseases, Inborn (12) · Ichthyosis (12) · Keratosis (12) · Skin Abnormalities (12) · Skin Diseases (12) · Skin Diseases, Genetic (12) · Skin and Connective Tissue Diseases (12) · Dermatitis (2) · Hypersensitivity (2) · Hypersensitivity, Immediate (2) · Immune System Diseases (2) · Skin Diseases, Eczematous (2) · Wounds and Injuries (2)
Isotretinoin (1) · Patient Reported Outcome Measures (1) · Standard of Care (1) · Surveys and Questionnaires (1) · Transplantation, Autologous (1) · Ustekinumab (1) · dupilumab (1) · secukinumab (1)
Kerecis Ltd. (3) · Maastricht University Medical Center (2) · Crown Laboratories, Inc. (1) · LEO Pharma (1) · National Medical Research Center for Children's Health, Russian Federation (1) · Northwestern University (1) · Patagonia Pharmaceuticals, LLC (1) · St. James's Hospital, Ireland (1) · University of Aarhus (1)
United States (6) · Netherlands (2) · Australia (1) · Denmark (1) · France (1) · Ireland (1) · Russia (1)
Alan Irvine (1) · Amy S Paller, MD (1) · Antoni C Gostynski, MD, PhD (1) · Antoni H Gostynski, MD, PhD (1) · Dured Dardari, MD, PhD (1) · Jeffrey W. Shupp, MD (1) · Uffe Koppelhus, MD, PhD (1) · Zachary Rome, BS (1)