5 completed, 1 not yet recruiting, 1 terminated. 3 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 2 | Completed 2 |
Follow Ichthyosis, Lamellar: new trials by email Literature Review of Ichthyosis, Lamellar trials Research Report on Ichthyosis, Lamellar
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lymphocyte Phenotype of Autosomal Recessive Congenital Ichthyoses Mutated NIPAL4 (Nipal4-nEDD) blood sampling - Sezary Syndrome, Ichthyosis, Lamellar | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 10 | 2026-04-01 | 2026-03-17 | |
| A Safety, Efficacy and Systemic Exposure Study of CD5789 Cream in Adults and Adolescents With Lamellar Ichthyosis CD5789 Cream 200 µg/g, CD5789 Cream 100 µg/g, CD5789 Cream Vehicle - Lamellar Ichthyosis | Phase 2 | Terminated | Mayne Pharma International Pty Ltd | 65 | 2019-05-01 | 2023-08-14 |
| The Efficacy and Safety of Secukinumab in Patients With Ichthyoses Secukinumab, Placebo - Ichthyosis, Autosomal Recessive Congenital Ichthyosis | Phase 2 | Completed | Northwestern University | 20 | 2016-12-01 | 2021-08-25 |
| Treatment of the Recessive Nonbullous Congenital Ichthyosis by the Epigallocatechine Cutaneous apply VEREGEN ® 10 % on a randomized area and the moisturizing cream of the other side - Lamellar Ichthyosis | Phase 3 | Completed | Centre Hospitalier Universitaire de Nice | 6 | 2010-10-01 | 2026-06-17 |
| Efficacy and Safety of Two Doses of Liarozole vs. Placebo for the Treatment of Lamellar Ichthyosis Liarozole - Ichthyosis, Lamellar | Phase 2 / Phase 3 | Completed | Stiefel, a GSK Company | 98 | 2006-01-01 | 2011-09-26 |
| National Registry for Ichthyosis and Related Disorders Darier Disease, Hailey-Hailey Disease | Completed | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 610 | 1994-09-01 | 2022-09-28 | |
| Study of Scaling Disorders and Other Inherited Skin Diseases Genetic Skin Disease, Keratosis Follicularis | Completed | National Cancer Institute (NCI) | 1992-02-01 | 2008-03-05 |
Ichthyosis (3) · Darier Disease (2) · Hyperkeratosis, Epidermolytic (2) · Ichthyosiform Erythroderma, Congenital (2) · Dermatitis, Exfoliative (1) · Epidermal Nevus (1) · Ichthyosis, X-Linked (1) · Keratosis (1) · Nails, Malformed (1) · Netherton Syndrome (1) · Pemphigus, Benign Familial (1) · Sezary Syndrome (1) · Skin Diseases, Genetic (1)
Congenital Abnormalities (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Genetic Diseases, Inborn (7) · Infant, Newborn, Diseases (7) · Skin Abnormalities (7) · Skin Diseases (7) · Skin and Connective Tissue Diseases (7) · Keratosis (6) · Skin Diseases, Genetic (6) · Ichthyosiform Erythroderma, Congenital (5) · Ichthyosis (4) · Abnormalities, Multiple (1) · Dermatitis (1) · Genetic Diseases, X-Linked (1) · Hemic and Lymphatic Diseases (1)
Blood Specimen Collection (1) · liarozole (1) · secukinumab (1) · trifarotene (1)
Assistance Publique - Hôpitaux de Paris (1) · Centre Hospitalier Universitaire de Nice (1) · Mayne Pharma International Pty Ltd (1) · National Cancer Institute (NCI) (1) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (1) · Northwestern University (1) · Stiefel, a GSK Company (1)
United States (4) · France (3) · Canada (2) · Germany (2) · Australia (1) · Belgium (1) · Dominican Republic (1) · Israel (1) · Italy (1) · Netherlands (1) · Norway (1) · Spain (1) · Sweden (1) · Ukraine (1) · United Kingdom (1)
Amy Paller, MD (1) · Chiaverini Christine, Dr (1) · Emma Guttman-Yassky, MD, PhD (1) · Keith A. Choate, MD (1) · Koen van Rossem, MD, PhD (1) · Philip Fleckman, MD (1)
PMID 11511292, PMID 11912510, PMID 12648223, PMID 14734878, PMID 15238912, PMID 16250204, PMID 18571597, PMID 18948357, PMID 19241467, PMID 24102348, PMID 35218370, PMID 9804339, PMID 9843209