5 completed, 1 recruiting. 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Sjogren-Larsson Syndrome: new trials by email Literature Review of Sjogren-Larsson Syndrome trials Research Report on Sjogren-Larsson Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ADX-629 Therapy for Sjogren-Larsson Syndrome ADX-629 - Sjogren-Larsson Syndrome | Phase 1 / Phase 2 | Completed | University of Nebraska | 8 | 2023-01-02 | 2026-05-05 |
| RESET Trial - Part 1 - A Phase 3 Trial in Subjects With Sjögren-Larsson Syndrome (SLS) ADX-102 1% Topical Dermal Cream (reproxalap), Vehicle of ADX-102 Topical Dermal Cream - Sjogren-Larsson Syndrome | Phase 3 | Completed | Aldeyra Therapeutics, Inc. | 11 | 2018-07-18 | 2023-02-09 |
| LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies Leukodystrophy, White Matter Disease | Completed | Children's Hospital of Philadelphia | 236 | 2017-01-06 | 2025-11-10 | |
| The Myelin Disorders Biorepository Project Leukodystrophy, White Matter Disease | Recruiting | Children's Hospital of Philadelphia | 12000 | 2016-12-08 | 2025-10-23 | |
| A Study of Topical NS2 Cream to Treat Ichthyosis in Sjögren-Larsson Syndrome (SLS) Active topical NS2 1% dermatologic cream, Vehicle placebo 0.0% NS2 dermatologic cream - Sjögren-Larsson Syndrome | Phase 2 | Completed | Aldeyra Therapeutics, Inc. | 12 | 2015-03-01 | 2022-12-13 |
| Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers Sjogren-Larsson Syndrome (SLS) | Completed | University of Nebraska | 20 | 2013-04-01 | 2024-10-08 |
Ichthyosis (3) · Adrenoleukodystrophy (2) · Aicardi-Goutieres syndrome (2) · Alexander Disease (2) · Alexanders leukodystrophy (2) · Allan-Herndon-Dudley syndrome (2) · Attention Deficit Disorder with Hyperactivity (2) · CADASIL (2) · Canavan Disease (2) · Cerebral Palsy (2) · Charcot-Marie-Tooth Disease (2) · Cockayne Syndrome (2) · Gangliosidoses (2) · Gangliosidoses, GM2 (2)
Congenital Abnormalities (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Infant, Newborn, Diseases (6) · Keratosis (6) · Lipid Metabolism Disorders (6) · Lipid Metabolism, Inborn Errors (6) · Lipidoses (6) · Metabolic Diseases (6) · Metabolism, Inborn Errors (6) · Nutritional and Metabolic Diseases (6) · Skin Abnormalities (6) · Skin Diseases (6) · Skin Diseases, Genetic (6) · Skin and Connective Tissue Diseases (6)
ADX-629 (1) · Skin Cream (1) · reproxalap (1)
Aldeyra Therapeutics, Inc. (2) · Children's Hospital of Philadelphia (2) · University of Nebraska (2)
United States (6)
Adeline Vanderver, MD (2) · William B Rizzo, MD (2) · William B. Rizzo, MD (1)
U01NS106845 (1), U54NS115052 (1)