29 completed, 8 unknown, 2 recruiting, 1 not yet recruiting. 12 Phase 4, 10 Phase 3, 9 Phase 2, 4 Not applicable, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 9, Unknown 2, Not yet recruiting 1 |
| Phase 3 | 10 | Completed 8, Unknown 2 |
| Phase 2 | 9 | Completed 7, Recruiting 2 |
| Not applicable | 4 | Completed 2, Unknown 2 |
| Phase 1 | 4 | Completed 4 |
Follow rebamipide: new trials by email Literature Review of rebamipide trials Research Report on rebamipide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study Comparing Diosmin vs Rebamipide as Adjuvant Therapies vs Conventional Therapy in Patients With Rheumatoid Arthritis Diosmin, Rebamipide 100mg, Convential medical treatment - Rheumatoid Arthritis (RA) | Phase 2 | Recruiting | Tanta University | 66 | 2026-08-01 | 2026-08-04 |
| Evaluation of Topical Rebamipide Versus Topical Betamethasone for Treatment of Oral Aphthous Ulcers Rebamipide mouthwash, Betamethasone mouthwash - Oral Aphthous Ulcers | Phase 2 | Recruiting | Cairo University | 46 | 2026-07-01 | 2026-10-06 |
| Rebamipide Versus Diquafosol for Perioperative Dry Eye in Cataract Surgery Rebamipide 2% ophthalmic solution, Diquafosol 3% ophthalmic solution - Dry Eye Disease (DED), Cataract | Phase 4 | Not yet recruiting | Samsung Medical Center | 60 | 2026-03-01 | 2026-02-09 |
| Rebamipide Versus Diquafosol and Cyclosporine for Perioperative Dry Eye in Cataract Surgery Rebamipide 2% ophthalmic solution, Diquafosol 3% ophthalmic solution, Cyclosporine 0.05% ophthalmic solution - Dry Eye Disease (DED), Cataract | Phase 4 | Completed | Samsung Medical Center | 56 | 2025-08-01 | 2026-10-27 |
| Rebamipide in Patients With Active Rheumatoid Arthritis Rebamipide, Placebo - Rheumatoid Arthritis | Phase 1 / Phase 2 | Completed | October 6 University | 60 | 2024-01-01 | 2025-11-20 |
| Immediate Therapeutic Effects of Diquafosol and Rebamipide in Dry Eye Disease 3% diquafosol (right eye) and 2% rebamipide (left eye), 2% rebamipide (right eye) and 3% diquafosol (left eye) - Dry Eye Disease (DED) | Phase 4 | Completed | Korea University Anam Hospital | 30 | 2022-10-03 | 2025-12-22 |
| Gastroprotective Efficacy of Rebamipide in Patients With Atrial Fibrillation Treated With DOACs Rebamipide 100mg, Pantoprazole - Atrial Fibrillation (AF) | Phase 4 | Completed | Pirogov Russian National Research Medical University | 210 | 2022-01-11 | 2026-01-21 |
| Post-Marketing Surveillance of Safety and Effectiveness of Mucosta®SR Tab. Mucosta®SR Tablets 150mg(Rebamipide) - Acute Gastritis, Chronic Gastritis | Unknown | Korea Otsuka Pharmaceutical Co., Ltd. | 600 | 2021-10-07 | 2023-09-28 | |
| Compare the Effect of Eupatilin and Rebamipide on the Prevention of Gastroenteropathy Eupatilin, Rebamipide - Rheumatoid Arthritis, Osteoarthritis | Phase 4 | Unknown | Seoul National University Boramae Hospital | 50 | 2021-06-01 | 2021-05-13 |
| Rebamipide (Regular & Nanoparticulated) vs. Clobetasol in Management of Methotrexate-Induced Oral Ulceration in Rheumatoid Arthritis Patients Rebamipide, Nanoparticulated Rebamipide, Clobetasol Propionate - Rheumatoid Arthritis | Phase 3 | Unknown | Cairo University | 39 | 2020-12-01 | 2023-09-21 |
| h.Pylori Ttt With Rebamipide Rebamipide - H.Pylori Infection | Unknown | Assiut University | 60 | 2020-09-05 | 2020-09-16 | |
| Rebamipide AND Sjögren Syndrome Rebamipide - Improving Symptoms of Dry Mouth in Sjőgren's Syndrome | Not applicable | Unknown | University of Alexandria | 55 | 2020-03-13 | 2020-03-31 |
| Clinical Trial to Evaluate the Efficacy and Safety of CKD-495 Tablet CKD-495 75mg, CKD-495 150mg, Artemisiae argyi folium 95% ethanol ext.(20→1) 60mg - Gastritis | Phase 2 | Completed | Chong Kun Dang Pharmaceutical | 250 | 2018-01-16 | 2018-10-31 |
| Comparison Between Rebamipide 2% Versus Autologous Serum Rebamipide, autologous serum, autologous serum and rebamipide 2% - Dry Eye Syndromes, Sjögren Syndrome | Phase 4 | Completed | Hospital Nacional Profesor Alejandro Posadas | 21 | 2017-02-06 | 2018-12-04 |
| Clinical Study to Investigate the Pharmacokinetics and Safety/Tolerability of SA001 in Healthy Male Volunteers SA001 240mg + Rebamipide 200mg or Placebo, SA001 480mg or Placebo, SA001 710mg + Rebamipide 600mg or Placebo - Healthy | Phase 1 | Completed | Samjin Pharmaceutical Co., Ltd. | 56 | 2016-06-07 | 2022-03-31 |
| The Effect of Proton Pump Inhibitor and Polaprezinc Combination Therapy for Healing of Endoscopic Submucosal Dissection-induced Ulcer Polaprezinc, Rebamipide - Gastric Adenoma, Early Gastric Cancer | Not applicable | Completed | Yonsei University | 153 | 2015-01-14 | 2019-03-27 |
| Evaluation of Rebamipide and Rabeprazole Effect Associated or Not to Prevent Naproxen-induced Gastric Lesions 550 mg naproxen + 300 mg rebamipide + 20 mg rabeprazole., 550 mg naproxen + placebo + 20 mg rabeprazole, 550 mg naproxen + 300 mg rebamipide + placebo - Gastric Lesion | Phase 3 | Completed | Galeno Desenvolvimento de Pesquisas Clínicas | 32 | 2014-11-12 | 2018-09-05 |
| Rebamipide in Combination With Esomeprazole in the Management of Asian Patients With Functional Dyspepsia Rebamipide, Placebo (for Esomeprazole), Esomeprazole - Dyspepsia | Phase 4 | Unknown | University of Malaya | 200 | 2014-08-01 | 2016-01-05 |
| A Study to Evaluate REbamiPide as an Adjuvant Regimen to Heal erosIve Reflux Esophagitis Lansoprazole, Rebamipide, Rebamipide-placebo - Gastroesophageal Reflux | Phase 4 | Completed | YongChan Lee | 143 | 2014-01-01 | 2016-04-29 |
| A Drug Interaction Study of Mosapride and Rebamipide Rebamipide, Mosapride citrate - Healthy | Phase 1 | Completed | IlDong Pharmaceutical Co Ltd | 40 | 2013-05-01 | 2014-04-08 |
Showing 20 of 40. Sign in to see all of them.
Dry Eye Syndromes (11) · Arthritis, Rheumatoid (5) · Stomach Ulcer (5) · Keratoconjunctivitis Sicca (4) · Gastritis (3) · Cataract (2) · Dyspepsia (2) · Osteoarthritis (2) · Sjogren's Syndrome (2) · Spondylitis, Ankylosing (2) · Xerostomia (2) · Atrial Fibrillation (1) · Colitis, Ulcerative (1) · Enteritis (1) · Foot-and-Mouth Disease (1)
Otsuka Pharmaceutical Co., Ltd. (5) · Kubota Vision Inc. (3) · Cairo University (2) · Korea Otsuka Pharmaceutical Co., Ltd. (2) · Otsuka Pharmaceutical Development & Commercialization, Inc. (2) · Samsung Medical Center (2) · Assiut University (1) · BangMao Wang (1) · Chong Kun Dang Pharmaceutical (1) · Dong-A Pharmaceutical Co., Ltd. (1) · Galeno Desenvolvimento de Pesquisas Clínicas (1) · Hanlim Pharm. Co., Ltd. (1) · Hospital Nacional Profesor Alejandro Posadas (1) · IlDong Pharmaceutical Co Ltd (1) · Kangdong Sacred Heart Hospital (1)
South Korea (13) · Japan (6) · Egypt (5) · United States (5) · China (2) · Argentina (1) · Brazil (1) · Indonesia (1) · Malaysia (1) · Pakistan (1) · Philippines (1) · Russia (1)
Katsuhisa Saito (3) · Anna Abou-Raya, MD PhD (1) · Asmaa Elsayed (1) · Aziz Rani, MD (1) · Byung Chul Yoon, M.D., Ph.D. (1) · Chan Kook Park, M.D., Ph.D. (1) · Chun-ok Kim, MD (1) · Dong Ho Lee, M.D.,Ph.D. (1) · Dr. Laeeque Ahmed, Asst. Professor (1) · Eiji Murakami (1) · Emiliano Fa Ross, MD (1) · Engy Wahsh (1) · Esraa Abdallah (1) · Gary Foulks, MD (1)