7 completed. 7 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 7 |
| Phase 1 | 3 | Completed 3 |
Follow Ischemic Cardiomyopathy: new trials by email Literature Review of Ischemic Cardiomyopathy trials Research Report on Ischemic Cardiomyopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combination of Mesenchymal and C-kit+ Cardiac Stem Cells as Regenerative Therapy for Heart Failure Mesenchymal Stem Cells (MSC), c-kit+ cells, Placebo (Plasmalyte A) - Ischemic Cardiomyopathy | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 125 | 2015-10-01 | 2021-04-26 |
| Clinical Trial of Manganese-Enhanced MRI (MEMRI) to Assess Peri-Infarct Injury Manganese-enhanced MRI contrast reagent, Gadolinium-enhanced MRI contrast reagent - ISCHEMIC CARDIOMYOPATHY | Phase 1 / Phase 2 | Completed | Stanford University | 33 | 2015-04-01 | 2020-02-17 |
| Efficacy of EVP 1001-1 (SeeMore) in the Assessment of Myocardial Viability in Patients With Cardiovascular Disease 'SEEMORE' - MANGANESE-ENHANCED MRI CONTRAST REAGENT - ISCHEMIC CARDIOMYOPATHY | Phase 1 / Phase 2 | Completed | Stanford University | 6 | 2013-05-01 | 2017-01-02 |
| Allogeneic Stem Cells Implantation Combined With Coronary Bypass Grafting in Patients With Ischemic Cardiomyopathy Intramyocardial implantation of of a novel mesenchymal precursor cell type (iMP). - Coronary Artery Disease, Ischemic Cardiomyopathy | Phase 2 | Completed | AHEPA University Hospital | 11 | 2012-11-01 | 2019-05-07 |
| A Study of Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure AAV1/SERCA2a (MYDICAR), Placebo - Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy | Phase 2 | Completed | Celladon Corporation | 250 | 2012-07-01 | 2016-03-24 |
| Mesenchymal Stem Cells to Treat Ischemic Cardiomyopathy MSCs injection - Ischemic Cardiomyopathy | Phase 1 / Phase 2 | Completed | Alexandra Cristina Senegaglia | 10 | 2010-01-01 | 2017-12-13 |
| Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study) Adult stem cells, Placebo - Chronic Ischemic Heart Disease, Left Ventricular Dysfunction | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 92 | 2009-03-01 | 2015-07-01 |
Heart Failure (4) · Cardiovascular Diseases (2) · Coronary Artery Disease (2) · Heart Diseases (2) · Myocardial Infarction (2) · Ventricular Dysfunction, Left (2) · Angina Pectoris (1) · Arteriosclerosis (1) · Cardiomegaly (1) · Cardiomyopathies (1) · Coronary Disease (1) · Ischemia (1) · Myocardial Ischemia (1) · Ventricular Dysfunction (1)
Cardiovascular Diseases (5) · Heart Diseases (5) · Pathological Conditions, Signs and Symptoms (5) · Vascular Diseases (5) · Myocardial Ischemia (4) · Pathologic Processes (3) · Arterial Occlusive Diseases (2) · Infarction (2) · Ischemia (2) · Necrosis (2) · Ventricular Dysfunction (2) · Arteriosclerosis (1) · Chest Pain (1) · Coronary Disease (1) · Hypertrophy (1)
EVP 1001-1 (1) · Gadolinium DTPA (1) · Inosine Monophosphate (1) · Plasmalyte A (1) · Serum Albumin, Human (1)
Stanford University (2) · The University of Texas Health Science Center, Houston (2) · AHEPA University Hospital (1) · Alexandra Cristina Senegaglia (1) · Celladon Corporation (1)
United States (5) · Belgium (1) · Brazil (1) · Denmark (1) · Germany (1) · Greece (1) · Hungary (1) · Israel (1) · Netherlands (1) · Poland (1) · Sweden (1) · United Kingdom (1)
Robert Simari, MD (2) · Kyriakos Anastasiadis, MD, PhD FETCS (1) · Paulo Brofman, PhD (1) · Phillip C Yang, MD (1) · Phillip C. Yang, MD (1)
PMID 22447880, PMID 24622121, PMID 25136078, PMID 26803443, PMID 34315432, PMID 42003602
5UM1HL087318 (1), U01HL087318 (1)