5 completed, 2 not yet recruiting, 1 recruiting, 1 unknown. 9 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 5, Not yet recruiting 2, Recruiting 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Hookworm Infections: new trials by email Literature Review of Hookworm Infections trials Research Report on Hookworm Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Not yet recruiting | Swiss Tropical & Public Health Institute | 315 | 2026-11-06 | 2026-08-14 |
| Combination Therapies for Trichuris Trichiura Infection in Schoolchildren in Honduras Placebo, Albendazole 400 mg, Albendazole Plus Ivermectin - Trichuriasis, Strongyloidiasis | Phase 3 | Not yet recruiting | Mundo Sano Foundation | 368 | 2026-11-01 | 2026-06-23 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Completed | Swiss Tropical & Public Health Institute | 315 | 2025-11-25 | 2026-10-08 |
| Real World Evaluation of an Albendazole-Ivermectin Coformulation Safety and Effectiveness Pre-screening Phase, Screenig Phase, Randomization - Soil-Transmitted Helminths | Phase 3 | Recruiting | Insud Pharma | 20000 | 2025-09-01 | 2025-09-15 |
| Efficacy and Safety of Moxidectin-Albendazole Co-administration in SAC Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Placebo Moxidectin - Trichuriasis, Ascariasis | Phase 3 | Completed | Jennifer Keiser | 224 | 2024-05-14 | 2025-09-19 |
| Efficacy and Safety of MOX/ALB Co-administration Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Ivermectin 3 mg Oral Tablet - Trichuriasis, Ascariasis | Phase 3 | Completed | Jennifer Keiser | 255 | 2021-06-15 | 2024-01-24 |
| Adjunctive Ivermectin Mass Drug Administration for Malaria Control Ivermectin, Placebo, Dihydroartemisinin-piperaquine - Malaria,Falciparum, Neglected Tropical Diseases | Phase 3 | Unknown | London School of Hygiene and Tropical Medicine | 24000 | 2021-05-03 | 2022-02-24 |
| Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration moxidectin (8 mg) / albendazole (400 mg), ivermectin (200 µg/kg) / albendazole (400 mg), ALBENDAZOLE 400 Mg ORAL TABLET [ZENTEL] - Trichuriasis, Ascariasis | Phase 2 / Phase 3 | Completed | Jennifer Keiser | 536 | 2021-03-01 | 2024-12-05 |
| Comparative Efficacy of Different Mebendazole Polymorphs in the Treatment of Soil-transmitted Helminth Infections Mebendazole polymorph A and C 500 mg, Mebendazole polymorph C, Placebo - Necator Americanus Infection | Phase 3 | Completed | University of Kelaniya | 214 | 2011-05-01 | 2013-04-22 |
Ancylostomiasis (7) · Trichuriasis (6) · Ascariasis (4) · Enterobiasis (2) · Strongyloidiasis (2) · Elephantiasis, Filarial (1) · Helminthiasis (1) · Intestinal Diseases, Parasitic (1) · Malaria (1) · Malaria, Falciparum (1) · Neglected Diseases (1) · Scabies (1)
Infections (9) · Nematode Infections (9) · Parasitic Diseases (9) · Secernentea Infections (9) · Strongylida Infections (9) · Helminthiasis (8) · Adenophorea Infections (6) · Enoplida Infections (6) · Ascaridida Infections (4) · Oxyuriasis (2) · Oxyurida Infections (2) · Rhabditida Infections (2) · Digestive System Diseases (1) · Disease Attributes (1)
Albendazole (4) · Ivermectin (4) · Tablets (3) · moxidectin (3) · Bay 44-4400 (2) · Mebendazole (2) · emodepside (2) · Mass Drug Administration (1) · Random Allocation (1) · Watchful Waiting (1)
Jennifer Keiser (3) · Swiss Tropical & Public Health Institute (2) · Insud Pharma (1) · London School of Hygiene and Tropical Medicine (1) · Mundo Sano Foundation (1) · University of Kelaniya (1)
Tanzania (3) · Côte d’Ivoire (1) · Ghana (1) · Guinea-Bissau (1) · Honduras (1) · Kenya (1) · Philippines (1) · Sri Lanka (1)
Jennifer Keiser, Professor (2) · Alejandro Javier Krolewiecki, PhD, MD (1) · Alejandro Krolewiecki, MD (1) · Anna R Last, MBChB PhD (1) · Gabriela Matamoros, PhD, MSc, BSc (1) · Nilanthi R de Silva, MD (1) · Said Mohammed Ali, MSc (1)
PMID 34632308, PMID 36354034, PMID 37357904, PMID 37419638, PMID 39551062, PMID 40675166