9 completed, 1 withdrawn. 10 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 9, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Hookworm Infections: new trials by email Literature Review of Hookworm Infections trials Research Report on Hookworm Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Oxantel Pamoate in Children Infected With Trichuris Trichiura Oxantel Pamoate, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 2 | Completed | Jennifer Keiser | 163 | 2025-04-16 | 2025-06-08 |
| Efficacy, Safety and Acceptability of Ivermectin ODT in PSAC Ivermectin 1.5 mg ODT, Ivermectin 3 mg Oral Tablet, Albendazole 400 mg Oral Tablet - Trichuriasis, Ascariasis | Phase 2 | Completed | Jennifer Keiser | 260 | 2024-06-05 | 2025-09-22 |
| Efficacy and Safety of Emodepside in Adolescents and Adults Infected With Hookworm Emodepside, Albendazole 400mg - Hookworm Infections | Phase 2 | Completed | Jennifer Keiser | 320 | 2022-09-16 | 2023-06-15 |
| Efficacy and Safety of Emodepside in Adults Infected With Trichuris Trichiura and Hookworm Emodepside - Trichuris Trichiura; Infection, Hookworm Infections | Phase 2 | Completed | Jennifer Keiser | 442 | 2021-08-02 | 2022-05-27 |
| Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration moxidectin (8 mg) / albendazole (400 mg), ivermectin (200 µg/kg) / albendazole (400 mg), ALBENDAZOLE 400 Mg ORAL TABLET [ZENTEL] - Trichuriasis, Ascariasis | Phase 2 / Phase 3 | Completed | Jennifer Keiser | 536 | 2021-03-01 | 2024-12-05 |
| Study of the Efficacy of Oxfendazole Compared to Albendazole in the Treatment of Trichuris Trichiura Infection in Adults oxfendazole, albendazole - Helminthiasis | Phase 2 | Withdrawn | Johns Hopkins Bloomberg School of Public Health | 2019-11-01 | 2019-08-15 | |
| Efficacy and Safety of a New Chewable Versus the Swallowable Tablet of Mebendazole Against Hookworm Mebendazole - Hookworm Infections | Phase 2 | Completed | Swiss Tropical & Public Health Institute | 397 | 2019-07-12 | 2020-07-20 |
| Albendazole Dose Finding and Pharmacokinetics in Children and Adults Albendazole, Placebo - Trichuriasis, Hookworm Infections | Phase 2 | Completed | Jennifer Keiser | 700 | 2018-10-23 | 2023-06-12 |
| Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection Na-GST-1/Alhydrogel, Na-GST-1/Alhydrogel + CPG 10104, Na-GST-1/Alhydrogel + GLA-AF - Hookworm Infections | Phase 2 | Completed | Baylor College of Medicine | 39 | 2018-03-01 | 2026-03-12 |
| Desensitising Celiac Disease Patients With the Human Hookworm Necator americanus - Celiac Disease | Phase 1 / Phase 2 | Completed | The Prince Charles Hospital | 12 | 2012-08-01 | 2014-10-20 |
Ancylostomiasis (6) · Trichuriasis (5) · Ascariasis (2) · Helminthiasis (2) · Celiac Disease (1) · Intestinal Diseases, Parasitic (1)
Infections (10) · Nematode Infections (10) · Parasitic Diseases (10) · Secernentea Infections (10) · Strongylida Infections (10) · Helminthiasis (8) · Adenophorea Infections (5) · Enoplida Infections (5) · Ascaridida Infections (2) · Digestive System Diseases (2) · Gastrointestinal Diseases (2) · Intestinal Diseases (2) · Malabsorption Syndromes (1) · Metabolic Diseases (1)
Albendazole (6) · Ivermectin (2) · Mebendazole (2) · Tablets (2) · emodepside (2) · ASP-1 protein, Necator americanus (1) · moxidectin (1) · oxantel pamoate (1) · oxfendazole (1)
Jennifer Keiser (6) · Baylor College of Medicine (1) · Johns Hopkins Bloomberg School of Public Health (1) · Swiss Tropical & Public Health Institute (1) · The Prince Charles Hospital (1)
Tanzania (6) · Australia (1) · Côte d’Ivoire (1) · United States (1)
Jennifer Keiser, PhD (2) · Alexander Loukas, PhD (1) · Armando E Gonzalez, DVM, PhD (1) · David Diemert, MD (1) · Dianne Jones, BAppSc (1) · Hector H Garcia, MD, PhD (1) · John Croese, MD (1) · Richard J Horton, MB BChir, MRCGP, FFPM (1) · Robert H Gilman, MD (1)
PMID 32405623, PMID 32668456, PMID 33150325, PMID 34632308, PMID 36354034, PMID 37195942, PMID 37195949, PMID 39153818, PMID 40975108, PMID 41861834, PMID 42486129
U01AI129789 (1)