100 completed, 58 unknown, 46 recruiting, 19 not yet recruiting. 74 Not applicable, 16 Phase 2, 11 Phase 1, 10 Phase 3, 7 Phase 4.
Follow Digestive System Abnormalities: new trials by email Literature Review of Digestive System Abnormalities trials Research Report on Digestive System Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Butyrate Enemas on Postoperative Intestinal Motility Disorders in Hirschsprung's Disease Sodium Butyrate, routine management - Hirschsprung's Disease | Phase 3 | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 58 | 2026-11-01 | 2026-09-10 |
| Tolerability of Enteral NAC in Infants N-Acetylcysteine - Biliary Atresia | Phase 1 | Not yet recruiting | Sanjiv Harpavat | 12 | 2026-10-01 | 2026-03-04 |
| Individualized Drainage Strategy Based on Risk Stratification in Children Undergoing Surgery for Choledochal Cyst: A Prospective Randomized Controlled Trial Robot-Assisted Roux-en-Y Hepaticojejunostomy with Drainage Management - Children Following Robot-assisted Roux-en-Y Hepaticojejunostomy for Choledochal Cysts, Choledochal Cyst | Not applicable | Not yet recruiting | Xueqiang Yan | 80 | 2026-09-01 | 2026-09-17 |
| Comparison of a New Non-invasive Device With the Invasive Gold-standard Investigation to Assess Function of the Large Bowel in Children Body Surface Colonic Mapping - Bowel Dysfunction, Dysmotility | Not applicable | Not yet recruiting | Murdoch Childrens Research Institute | 50 | 2026-09-01 | 2026-09-02 |
| Umbilical Cord Mesenchymal Stem Cell Therapy for Biliary Atresia Umbilical Cord-Mesenchymal Stem Cells (UC-MSC), Kasai Portoenterostomy - Biliary Atresia, Kasai Operation | Phase 1 | Recruiting | Dr Cipto Mangunkusumo General Hospital | 40 | 2026-09-01 | 2026-09-09 |
| Effectiveness of Electrical Stimulation and Biofeedback on Fecal Incontinence in Children With Repaired Anorectal Malformation behavioral therapy, biofeedback, electrical stimulation - Fecal Incontinence (FI), Anorectal Malformations | Not applicable | Not yet recruiting | Sinai University | 30 | 2026-08-03 | 2026-08-04 |
| Urinary and Sexual Symptoms in Patients With Hirschsprung Disease Type of pull-through procedure performed as part of routine clinical care (Swenson, Duhamel, or Soave). - Hirschsprung Disease | Not yet recruiting | University Hospital, Grenoble | 556 | 2026-08-01 | 2026-08-03 | |
| Pattern And Outcome Of Neonatal Gastrointestinal Emergencies In Assiut University Children Hospital Necrotizing Enterocolitis, Intestinal Atresia | Not yet recruiting | Assiut University | 120 | 2026-05-01 | 2026-04-13 | |
| Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia Questionnaires - Dental Diseases | Recruiting | University Hospital, Toulouse | 120 | 2026-04-07 | 2026-05-12 | |
| Surgical Approach for the Treatment of Hirschsprung Disease Using the Swenson Technique (SMILES) transanal or laparoscopy assisted Swenson coloanal pullthrough - Hirschsprung Disease | Not yet recruiting | University Hospital, Angers | 70 | 2026-03-01 | 2026-03-12 | |
| Role of (Saline- Glycerin) Rectal Enema in Treatment of Fecal Incontinence in Children Rectal enema using saline and glycerin mixture once daily - Anorectal Malformation | Early Phase 1 | Not yet recruiting | Sohag University | 30 | 2026-02-15 | 2026-02-06 |
| Outcomes in ARMs: Comparison Between Surgical Techniques in Patients With Perineal or Vestibular Fistula - a Multicenter Italian Study Anorectal Malformations | Recruiting | Meyer Children's Hospital IRCCS | 500 | 2026-02-05 | 2026-03-27 | |
| Robot/Laparoscopic-Assisted Transanal Transection Duhamel Versus Modified Soave Pull-Through for TCA Transanal Transection Duhamel operation, Modified Soave Pull-Through - Total Colonic Aganglionosis, Hirschsprung Disease | Not applicable | Not yet recruiting | Zunyi Medical College | 50 | 2026-01-30 | 2026-01-15 |
| The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis Indocyanine Green - Biliary Atresia, Kasai | Early Phase 1 | Recruiting | University of Alabama at Birmingham | 15 | 2026-01-23 | 2026-02-18 |
| Factors Affecting Postoperative Recovery From Common Bile Duct Cysts in Children: A Multicenter Retrospective Analysis Based on Perioperative Clinical Characteristics Choledochal Cyst Resection | Completed | Wuhan Children's Hospital | 550 | 2026-01-01 | 2026-09-02 | |
| Host-Microbe Interactions in Biliary Dilatation Choledochal Cyst | Not yet recruiting | Beijing Tsinghua Chang Gung Hospital | 400 | 2025-12-15 | 2025-12-09 | |
| Kasai Portoenterostomy Timing and Outcomes in Biliary Atresia Kasai portoenterostomy - Biliary Atresia | Completed | The Children's Hospital of Zhejiang University School of Medicine | 200 | 2025-12-01 | 2026-02-06 | |
| Brazilian Multicenter Study on Esophageal Atresia Esophageal Atresia | Not yet recruiting | University of Sao Paulo General Hospital | 1000 | 2025-11-01 | 2025-10-07 | |
| Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study Endoscopic Balloon Dilation - Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia | Not applicable | Recruiting | Boston Children's Hospital | 128 | 2025-10-28 | 2026-04-30 |
| Cholangitis Definition and Treatment After Kasai Hepatoportoenterostomy for Biliary Atresia: TRACK-BA Study (TRacking Cholangitis Post Kasai in Biliary Atresia) Biliary Atresia, Kasai Portoenterostomy Status, Cholangitis | Not yet recruiting | University Hospital, Geneva | 40 | 2025-10-01 | 2025-08-19 |
Showing 20 of 243. Sign in to see all of them.
Biliary Atresia (75) · Hirschsprung Disease (61) · Esophageal Atresia (37) · Anorectal Malformations (30) · Choledochal Cyst (20) · Intestinal Atresia (13) · Cholestasis (12) · Gastroschisis (11) · Cholangitis (10) · Enterocolitis, Necrotizing (10) · Premature Birth (7) · Fecal Incontinence (6) · Liver Cirrhosis (6) · Congenital Abnormalities (5)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (243) · Digestive System Diseases (241) · Congenital Abnormalities (238) · Gastrointestinal Diseases (122) · Biliary Tract Diseases (103) · Bile Duct Diseases (101) · Intestinal Diseases (83) · Colonic Diseases (61) · Megacolon (61) · Pathological Conditions, Signs and Symptoms (59) · Esophageal Diseases (41) · Neoplasms (29) · Pathological Conditions, Anatomical (29) · Pathologic Processes (28)
Portoenterostomy, Hepatic (6) · Surveys and Questionnaires (6) · Indocyanine Green (4) · Behavior Therapy (3) · Granulocyte Colony-Stimulating Factor (3) · Laparoscopy (3) · fish oil triglycerides (3) · Acetylcysteine (2) · Blood Specimen Collection (2) · Conversion to Open Surgery (2) · Endoscopic Mucosal Resection (2) · Filgrastim (2) · Immunoglobulins, Intravenous (2) · Meropenem (2) · Methylprednisolone (2)
Tongji Hospital (7) · University Hospital, Lille (7) · Children's Hospital of Fudan University (6) · Beijing Tsinghua Chang Gung Hospital (5) · Boston Children's Hospital (5) · Zunyi Medical College (5) · Assiut University (4) · National Taiwan University Hospital (4) · University Hospital, Angers (4) · Weibing Tang (4) · Yonsei University (4) · Alder Hey Children's NHS Foundation Trust (3) · Arbor Research Collaborative for Health (3) · Assistance Publique Hopitaux De Marseille (3) · Aswan University Hospital (3)
United States (52) · China (46) · France (28) · United Kingdom (16) · Canada (15) · Egypt (15) · Germany (12) · Netherlands (9) · Turkey (Türkiye) (8) · Vietnam (8) · Taiwan (7) · Denmark (6) · Italy (6) · Poland (6) · South Korea (6)
Ed Doo, MD (5) · Averell Sherker, MD (3) · John Magee, MD (3) · Lisa Henn, PhD (3) · Shuo Jin, PhD (3) · Weibing Tang, Dr (3) · Judy L Aschner, MD (2) · Katrina Loh, MD (2) · Laurent Michaud, MD (2) · Liem Nguyen (2) · Lynda Szczech, MD (2) · Mei-Hwei Chang, MD (2) · Quang T Nguyen, M.D. (2) · Ronald Sokol, MD (2)
PMID 15660319, PMID 20717739, PMID 26561627, PMID 26611332, PMID 26725209, PMID 29519540, PMID 33395367, PMID 34059040, PMID 35391541, PMID 11527163, PMID 11743518, PMID 11953745, PMID 12183720, PMID 1294807, PMID 12948306, PMID 13403593, PMID 14497096, PMID 15824939, PMID 15829955, PMID 15838576, PMID 15849514, PMID 16632990, PMID 17043852, PMID 17638154, PMID 18161934, PMID 18679744, PMID 19306335, PMID 19393505, PMID 19540516, PMID 19581853, PMID 20385264, PMID 20598273, PMID 21475026, PMID 21694639, PMID 22207929, PMID 22732895, PMID 22891232, PMID 22903006, PMID 23054338, PMID 23224913, PMID 23331802, PMID 23604057, PMID 24244109, PMID 24493287, PMID 24794368, PMID 25015575, PMID 25214022, PMID 25419594, PMID 25534776, PMID 25564820
U01DK062456 (5), U01DK062436 (3), U01DK062445 (3), U01DK062452 (3), U01DK062453 (3), U01DK062466 (3), U01DK062470 (3), U01DK062481 (3), U01DK062497 (3), U01DK062500 (3), U01DK062503 (3), U01DK084536 (3), U01DK084538 (3), U01DK084575 (3), U01DK103135 (3)