10 completed, 6 unknown, 4 recruiting, 3 not yet recruiting. 23 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 23 | Completed 10, Unknown 6, Recruiting 4, Not yet recruiting 3 |
Follow Hirschsprung Disease: new trials by email Literature Review of Hirschsprung Disease trials Research Report on Hirschsprung Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of a New Non-invasive Device With the Invasive Gold-standard Investigation to Assess Function of the Large Bowel in Children Body Surface Colonic Mapping - Bowel Dysfunction, Dysmotility | Not applicable | Not yet recruiting | Murdoch Childrens Research Institute | 50 | 2026-09-01 | 2026-09-02 |
| Robot/Laparoscopic-Assisted Transanal Transection Duhamel Versus Modified Soave Pull-Through for TCA Transanal Transection Duhamel operation, Modified Soave Pull-Through - Total Colonic Aganglionosis, Hirschsprung Disease | Not applicable | Not yet recruiting | Zunyi Medical College | 50 | 2026-01-30 | 2026-01-15 |
| Effects of Physiotherapy in Children With Hirschsprung's Disease Physiotherapy - Hirschsprung Disease | Not applicable | Not yet recruiting | Ankara Yildirim Beyazıt University | 20 | 2025-09-30 | 2025-09-05 |
| MSOT and MRI for Non-invasive Assessment of Intestinal Transit Time in Children With Chronic Bowel Emptying Disorders MSOT with ICG, MRI - Chronic Constipation, Slow Transit Constipation | Not applicable | Recruiting | Dr. med. Sonja Diez | 20 | 2025-04-15 | 2025-09-03 |
| Impact of Providing Nursing Support on Parental Stress Related to Preoperative Care of a Newborn with Hirschsprung's Disease Pediatric HAH - Hirschsprung Disease | Not applicable | Recruiting | Assistance Publique Hopitaux De Marseille | 20 | 2023-08-14 | 2024-10-21 |
| The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies Standard of Care, Exclusive Human Milk - Gastrointestinal Complication, Intestinal Obstruction | Not applicable | Recruiting | Seattle Children's Hospital | 116 | 2023-06-09 | 2026-04-30 |
| Full Thickness vs. Rectal Suction Biopsy in the Diagnosis of Hirschsprungs Disease Rectal suction biopsy., Full-thickness rectal biopsy. - Hirschsprung Disease | Not applicable | Unknown | University of Southern Denmark | 300 | 2022-01-01 | 2022-05-17 |
| Nutrition Support for Hirschsprung Disease supplement nutritional supporting - Nutrition Supporting, Hirschsprung Disease | Not applicable | Completed | Tongji Hospital | 110 | 2021-01-01 | 2023-04-04 |
| The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery. SPY imaging, Indocyanine Green - Intestinal Atresia, Necrotizing Enterocolitis | Not applicable | Completed | St. Justine's Hospital | 35 | 2020-03-16 | 2021-03-17 |
| Comparison of Robot-assisted With Laparoscopic-assisted Modified Soave Procedure for Classical Hirschsprung Disease RAMS, LAMS - Hirschsprung Disease | Not applicable | Unknown | Zunyi Medical College | 130 | 2020-02-07 | 2024-01-09 |
| Minimally Invasive Surgical Intervention for Hirschsprung Disease Minimally invasive laparoscopic pull-through surgery - Hirschsprung Disease | Not applicable | Completed | National Children's Hospital, Vietnam | 23 | 2020-01-01 | 2025-06-15 |
| eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness e-health device with application, Mobile phone text messaging, early detection of cerebral palsy using a mobile phone application - Preterm Birth, Pediatric Cancer | Not applicable | Completed | Lund University | 720 | 2019-10-15 | 2026-04-06 |
| Sacral Neuromodulation in Children and Adolescents Invasive Sacral Neuromodulation, Non-invasive Sacral Neuromodulation - Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence | Not applicable | Completed | Friedrich-Alexander-Universität Erlangen-Nürnberg | 48 | 2019-01-01 | 2025-09-08 |
| Improvement of Understanding of Pediatric Sacral Neuromodulation: Therapeutic Strategies and Outcome Variables SNM/MRI/EMG - Gastrointestinal Motility Disorders in Children, Hirschsprung Disease | Not applicable | Recruiting | Friedrich-Alexander-Universität Erlangen-Nürnberg | 25 | 2018-07-01 | 2026-04-09 |
| Neuropsychological Development and Functional Outcome Sin Children With Hirschsprung Disease at School Age psychometric evaluation, neuropsychological evaluation - Hirschsprung's Disease (HD) | Not applicable | Completed | Assistance Publique Hopitaux De Marseille | 2 | 2018-01-17 | 2026-05-08 |
| Probiotics and Post-Pullthrough Hirschsprung's Disease-Associated Enterocolitis Saccharomyces Boulardii Probiotic Supplement - Hirschsprung Disease, Enterocolitis | Not applicable | Completed | Aswan University Hospital | 88 | 2018-01-01 | 2025-08-01 |
| Laparoscopic Assisted Pull-through Versus Other Surgical Procedures for Treatment of Hirschsprung Disease laparoscopic assisted pull-through oeration - Hirschsprung Disease | Not applicable | Unknown | Assiut University | 60 | 2017-09-01 | 2017-09-01 |
| MICROPRUNG : Intestinal Microbiota Analysis in Patients With or Without Hirschsprung's Associated EnteroColitis Fecal samples - Hirschsprung Disease | Not applicable | Completed | Rennes University Hospital | 118 | 2016-06-01 | 2018-09-13 |
| Enhanced Recovery After Surgery In Hirschsprung Disease Enhanced Recovery After Surgery Program, Traditional Program - Hirschsprung Disease | Not applicable | Unknown | Weibing Tang | 200 | 2016-01-01 | 2016-05-19 |
| Electrophysiological Activity of the Anorectum in Children Suspected of Hirschsprung Disease Child suspected of Hirschsprung disease - Hirschsprungs Disease | Not applicable | Unknown | Rabin Medical Center | 20 | 2015-03-01 | 2015-01-21 |
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Anorectal Malformations (3) · Constipation (2) · Gastroschisis (2) · Intestinal Obstruction (2) · Volvulus Of Midgut (2) · Acquired Immunodeficiency Syndrome (1) · Child Nutrition Disorders (1) · Congenital Abnormalities (1) · Enterocolitis (1) · Enterocolitis, Necrotizing (1) · Heart Defects, Congenital (1) · Hernia, Umbilical (1) · Intestinal Atresia (1) · Intestinal Diseases (1)
Colonic Diseases (23) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (23) · Digestive System Abnormalities (23) · Digestive System Diseases (23) · Gastrointestinal Diseases (23) · Megacolon (23) · Congenital Abnormalities (22) · Intestinal Diseases (22) · Pathological Conditions, Signs and Symptoms (5) · Gastroenteritis (2) · Hernia (2) · Hernia, Abdominal (2) · Musculoskeletal Abnormalities (2) · Musculoskeletal Diseases (2) · Pathological Conditions, Anatomical (2)
Conservative Treatment (1) · Endoscopic Mucosal Resection (1) · Indocyanine Green (1) · Lactulose (1) · Mineral Oil (1) · Physical Therapy Modalities (1) · Self Care (1) · Standard of Care (1)
Assistance Publique Hopitaux De Marseille (2) · Friedrich-Alexander-Universität Erlangen-Nürnberg (2) · Tongji Hospital (2) · Zunyi Medical College (2) · Ankara Yildirim Beyazıt University (1) · Assiut University (1) · Aswan University Hospital (1) · Dr. med. Sonja Diez (1) · Lund University (1) · Massachusetts General Hospital (1) · Medical University of Warsaw (1) · Murdoch Childrens Research Institute (1) · National Children's Hospital, Vietnam (1) · Rabin Medical Center (1) · Rennes University Hospital (1)
China (5) · France (3) · Germany (3) · Denmark (2) · United States (2) · Australia (1) · Canada (1) · Egypt (1) · Ethiopia (1) · Poland (1) · Sweden (1) · Vietnam (1)
Adrian Regensburger, PD Dr. med. (1) · Braden Kuo, M.D. (1) · Enrique Freud, MD (1) · Jiexiong Feng, MD, PhD (1) · Katie Strobel, MD (1) · Marcin Banasiuk, MD (1)
PMID 15660319, PMID 20717739, PMID 26386879, PMID 26611332, PMID 28169931, PMID 31535199, PMID 31676258, PMID 32063371, PMID 32068552, PMID 33395367, PMID 33877661, PMID 34059040, PMID 35847080, PMID 35941653, PMID 37398887, PMID 37851500, PMID 37865736, PMID 38195486, PMID 38515199, PMID 39819595, PMID 41419466, PMID 42218492, PMID 42467022
2018 (1)