26 completed, 9 unknown, 6 recruiting, 4 not yet recruiting. 28 Not applicable, 3 Phase 4, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 28 | Completed 16, Not yet recruiting 4, Recruiting 4, Unknown 3, Active not recruiting 1 |
| Phase 4 | 3 | Unknown 2, Completed 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Hiatal Hernia: new trials by email Literature Review of Hiatal Hernia trials Research Report on Hiatal Hernia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Image-Guided Herniorrhaphy Study Image-Guided Herniorrhaphy - Hernia, Hernia Abdominal Wall | Not applicable | Not yet recruiting | University of California, Davis | 30 | 2026-12-01 | 2026-08-31 |
| Antireflux Surgery Without Preoperative Esophageal Manometry Preoperative workup without high-resolution esophageal manometry, Standard preoperative workup with high-resolution esophageal manometry - GERD, Hiatal Hernia | Not applicable | Not yet recruiting | McMaster University | 96 | 2026-10-01 | 2026-08-10 |
| Preoperative Predictors of Symptom Improvement After Laparoscopic Fundoplication Laparoscopic Nissen fundoplication, Laparoscopic Toupet fundoplication - Gastroesophageal Reflux Disease, Hiatal Hernia | Recruiting | Minia University | 470 | 2026-09-20 | 2026-09-22 | |
| Intrathoracic Sleeve Migration (Sliding Hiatal Hernia) One Year or More After Laparoscopic Sleeve Gastrectomy Laparoscopic sleeve gastrectomy, CT of the thorax and abdomen with oral water-soluble contrast - Hiatal Hernia, Gastroesophageal Reflux Disease | Completed | Kasr El Aini Hospital | 61 | 2026-04-01 | 2026-10-29 | |
| Evaluating Clinical Hiatal Hernia Outcomes Using OviTex® OviTex Reinforced Tissue Matrix - Hiatal Hernia | Not applicable | Recruiting | Tela Bio Inc | 173 | 2025-07-25 | 2026-08-18 |
| Laparoscopic Hiatal Hernia Repair With Mesh Cruroplasty Hiatal Hernia (HH) repair using mesh cruroplasty during a Laparoscopic Sleeve Gastrectomy (LSG) - Hiatal Hernia, Sleeve Gastrectomy | Not applicable | Completed | Zagazig University | 20 | 2025-06-26 | 2026-03-24 |
| Comparative 3-year Study of Nissen-sleeve vs. Sleeve Plus Cruroplasty in Obese Patients With Hiatal Hernia Ph-measurement, Questionnaires, gastroduodenal transit - Obesity, Hiatal Hernia | Not applicable | Not yet recruiting | Elsan | 150 | 2025-03-02 | 2025-02-19 |
| Nissen Versus Dor Hiatal Hernia Repair Nissen fundoplication, Dor fundoplication - Hiatal Hernia, Paraesophageal Hernia | Not applicable | Recruiting | Kuopio University Hospital | 150 | 2025-02-07 | 2025-02-19 |
| Laparoscopic Toupet's Fundoplication: Is it Proper Solution of Radiological Negative, Endoscopically Positive Hiatal Hernia Patients Laparoscopic toupet fundoplication - Laparoscopic Toupet Fundoplication, Radiological Negative | Not applicable | Completed | Minia University | 100 | 2024-10-01 | 2026-05-20 |
| Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair Biosynthetic Mesh, Hiatal Hernia Repair - Hiatal Hernia | Not applicable | Recruiting | Weill Medical College of Cornell University | 200 | 2024-06-10 | 2026-08-19 |
| Safety and Feasibility of Liver Retraction With the Levita Magnetic Surgical System: Extended Magnetic Grasper Device Extended Magnetic Grasper Device - Bariatric Surgery Candidate, Hiatal Hernia | Not applicable | Completed | Levita Magnetics | 30 | 2024-05-13 | 2025-05-29 |
| A Prospective Randomised Multi - Center Trial on the Repair of Large Hiatal Hernias: Absorbable Mesh vs. Pledgeted Sutures vs. Sutures Only Laparoscopic or robot-assisted hiatal closure (sutures only vs. absorbable mesh vs. pledgeted sutures) and fundoplication according to Toupet - Hiatal Hernia | Not applicable | Not yet recruiting | Paracelsus Medical University | 165 | 2024-05-01 | 2024-04-02 |
| Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia Opioid Sparing Anesthesia Protocol (OSA), Opioid Based Anesthesia Protocol (OBA) - Hiatal Hernia | Not applicable | Completed | Endeavor Health | 50 | 2024-03-03 | 2026-11-04 |
| Treatment of Reflux With Sleeve Gastrectomy Laparoscopic Sleeve Gastrectomy - Reflux Disease, Gastro-Esophageal, Hiatal Hernia | Not applicable | Unknown | Yusuf Emre ALTUNDAL | 80 | 2023-09-25 | 2023-12-27 |
| Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study) Body Weight, Post-Op Complication | Unknown | Dr. Med Anas Taha | 10000 | 2023-01-05 | 2023-02-02 | |
| Hiatal Hernia and Pulmonary Involvement Blood Collection, Bronchoscopy - Hiatal Hernia, Interstitial Lung Disease | Completed | University of Virginia | 14 | 2023-01-05 | 2026-03-16 | |
| Can EndoFLIP Improve Quality of Life Before and After Fundoplication? EndoFLIP - GERD, Hiatal Hernia | Not applicable | Unknown | Dr. Wiley Chung | 50 | 2023-01-05 | 2023-12-07 |
| Sutures Versus Polyglactin Mesh in Hiatal Hernia Repair Polyglactin mesh, Sutures only - Paraesophageal Hernia, Hiatal Hernia | Not applicable | Recruiting | Oulu University Hospital | 110 | 2022-01-21 | 2023-03-27 |
| Long-term Follow-up After Hiatal Hernia Repair by Tension-free Mesh Closure or Simple Suturing simple suturing, mesh - GERD, Hiatal Hernia | Completed | Karolinska University Hospital | 103 | 2021-09-15 | 2022-10-18 | |
| Pain Relief After Hiatal Hernia Repair Surgery Resteck Shiatsu Neck and Back Massager, Marcaine - Shoulder Pain, Hiatal Hernia | Phase 4 | Unknown | Norton Thoracic Institute | 90 | 2021-05-12 | 2021-06-23 |
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Hernia, Hiatal (47) · Gastroesophageal Reflux (22) · Esophagitis (4) · Recurrence (4) · Barrett Esophagus (3) · Esophagitis, Peptic (3) · Hernia (3) · Deglutition Disorders (2) · Heartburn (2) · Obesity (2) · Postoperative Complications (2) · Body Weight (1) · Cholecystitis (1) · Choledocholithiasis (1) · Diabetes Mellitus, Type 2 (1)
Pathological Conditions, Anatomical (47) · Pathological Conditions, Signs and Symptoms (47) · Hernia, Diaphragmatic (46) · Internal Hernia (46) · Hernia (44) · Digestive System Diseases (23) · Esophageal Motility Disorders (22) · Gastrointestinal Diseases (22) · Esophageal Diseases (21) · Deglutition Disorders (20) · Gastroenteritis (7) · Pathologic Processes (7) · Signs and Symptoms (7) · Neoplasms (5) · Disease Attributes (4)
Fundoplication (5) · Blood Specimen Collection (2) · Biopsy (1) · Bronchoscopy (1) · Bupivacaine (1) · Gastropexy (1) · Hydrogen-Ion Concentration (1) · Laparoscopy (1) · Melanocyte-Stimulating Hormones (1) · Surveys and Questionnaires (1) · Tumor Burden (1)
EndoGastric Solutions (3) · Minia University (2) · National Taiwan University Hospital (2) · University of Nebraska (2) · University of Washington (2) · Beijing Friendship Hospital (1) · Children's Mercy Hospital Kansas City (1) · Dr. Med Anas Taha (1) · Dr. Wiley Chung (1) · Elsan (1) · Endeavor Health (1) · Foregut Research Foundation (1) · G. Hatzikosta General Hospital (1) · Grubnik Volodymyr (1) · Karolinska Institutet (1)
United States (23) · Egypt (4) · Canada (2) · Finland (2) · France (2) · Sweden (2) · Taiwan (2) · Belgium (1) · Chile (1) · China (1) · Greece (1) · Italy (1) · Pakistan (1) · Switzerland (1) · Turkey (Türkiye) (1)
Dmitry Oleynikov, MD (2) · Abeer Fatima, MSPT-CPPT (1) · Ahmed Abdelsalam, MD (1) · Anders Thorell, Professor (1) · Bor-Ru Lin, M.D. (1) · Brant K Oelschlager, MD (1) · Brant K. Oelschlager, M.D. (1) · Brent D Matthews, MD (1) · Corey Deeken, PhD (1) · Evangelos C. Tsimoyiannis, M.D. chairman (1) · James D. Luketich, MD (1) · John Hunter, MD FACS (1) · John Kim, MD (1) · Lars Lundell, M.D. (1) · Michael Larson, MD (1)
PMID 19960205, PMID 25448925, PMID 26463242, PMID 32936951, PMID 33567462, PMID 35171266, PMID 37819652, PMID 40603619