90 completed, 20 unknown, 16 recruiting, 9 not yet recruiting. 51 Not applicable, 12 Phase 1, 10 Phase 3, 9 Phase 2, 5 Phase 4.
Follow Hemophilia: new trials by email Literature Review of Hemophilia trials Research Report on Hemophilia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Learn About the Study Medicine (Called Marstacimab) in People With Hemophilia A or B Marstacimab - Hemophilia | Not yet recruiting | Pfizer | 100 | 2026-10-05 | 2026-10-05 | |
| Validity and Reliability of the Figure-of-Eight Walking and Weight-Bearing Lunge Tests in Hemophilia Hemophilia | Recruiting | Yuzuncu Yil University | 36 | 2026-08-30 | 2026-10-01 | |
| 3D Ultrasound in Hemophilic Ankles Mechanical Ultrasound - Hemophilia | Not applicable | Enrolling by invitation | The Hospital for Sick Children | 11 | 2026-08-25 | 2026-10-14 |
| Prevalence of Inhibitor Development in Hemophilia A Patients Receiving Coageight: A Multicenter Cross-sectional Observational Study efmoroctocog alfa - Hemophilia A, Hemophilia | Not yet recruiting | AryoGen Pharmed Co. | 262 | 2026-08-23 | 2026-08-28 | |
| Multimodal Telerehabilitation Versus Face-to-Face Care for Adults With Hemophilia and Chronic Pain other, Exercise - Hemophilia, Chronic Pain | Not applicable | Recruiting | University of Chile | 24 | 2026-07-02 | 2026-07-07 |
| Central Pain Mechanisms and Clinical and Psychological Factors Associated With Pain Interference in Daily Life in Adults With Hemophilia and Hemophilic Arthropathy Hemophilia | Completed | Investigación en Hemofilia y Fisioterapia | 141 | 2026-04-22 | 2026-08-03 | |
| Effects of Photobiomodulation in Hemophilia Patients. photobiomodulation - Hemarthrosis, Knee, Hemophilia | Not applicable | Completed | Riphah International University | 24 | 2026-04-05 | 2026-09-30 |
| Oral Health Status and Oral Health Related Quality of Life in a Group pf Egyptian Hemophilic Children oral health educational program - Hemophilia | Not applicable | Not yet recruiting | Cairo University | 70 | 2026-04-01 | 2026-01-23 |
| Effectiveness of an Educational Program for Pain Management in Patients With Hemophilic Arthropathy Educational group - Hemophilia | Not applicable | Not yet recruiting | Investigación en Hemofilia y Fisioterapia | 70 | 2026-03-27 | 2026-02-20 |
| PCC Treatment for Hemophilia Patients With Inhibitor（2022PCC-A） PCC - Hemophilia, Inhibitors | Phase 4 | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 30 | 2026-03-01 | 2026-02-12 |
| Incidence of Ultrasonographically Detected Articular Damage in Initially Healthy Joints of Patients With Hemophilia A Receiving Prophylactic Treatment With Emicizumab Hemophilia patients - Hemophilia | Not yet recruiting | Investigación en Hemofilia y Fisioterapia | 70 | 2026-02-27 | 2026-02-20 | |
| Validity and Reliability of the Two-minute Step Test in Hemophilia Hemophilia, Step | Completed | Hasan Kalyoncu University | 31 | 2026-02-25 | 2026-09-23 | |
| Adult and Adolescent Hemophilia Patients Treated With Marstacimab: a Patient Experience Registry Marstacimab - Hemophilia | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 100 | 2026-02-15 | 2026-04-29 | |
| A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B Fitusiran, Clotting factor concentrates (CFC) or bypassing agents (BPA), Antithrombin concentrate (ATIIIC) - Hemophilia | Phase 3 | Recruiting | Sanofi | 85 | 2025-12-18 | 2026-10-19 |
| MRI Role in Knee Hemophilic Arthopathy MRI, Hemophilia | Not yet recruiting | Assiut University | 95 | 2025-12-01 | 2025-11-18 | |
| Monitoring of Anti-TFPI in Hemophilia blood sampling - Hemophilia, Rebalancing Agents | Recruiting | Hospices Civils de Lyon | 11 | 2025-10-23 | 2026-03-23 | |
| Physiotherapy to Improve Balance and Walking Capacity in Hemophilia Physiotherapy - Hemophilia | Not applicable | Completed | Yuzuncu Yil University | 35 | 2025-10-20 | 2026-01-14 |
| Tight Control of Treatment Adherence and Efficacy by Telemedicine for an Improved Personalized Management of Patients With Hemophilia TEMPO - Hemophilia | Not applicable | Recruiting | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 50 | 2025-10-19 | 2026-10-09 |
| Intra-Articular Bevacizumab for Preventing Recurrent Hemarthrosis in Hemophilia With Chronic Synovitis Intra-articular Bevacizumab - Hemophilia, Chronic Synovitis | Not applicable | Completed | Khyber Medical University Peshawar | 18 | 2025-09-09 | 2026-06-25 |
| Central Sensitisation in Patients With Haemophilia and Degenerative Arthropathy Hemophilia | Completed | Investigación en Hemofilia y Fisioterapia | 146 | 2025-08-01 | 2026-02-20 |
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Hemophilia A (156) · Hemophilia B (17) · Joint Diseases (15) · Chronic Pain (7) · Motor Activity (7) · Arthralgia (6) · Hemarthrosis (6) · Hemostatic Disorders (6) · Anxiety Disorders (5) · Thrombosis (5) · Anemia, Sickle Cell (4) · Heart Failure (4) · Hemorrhage (4) · Hepatitis C (4) · Osteoporosis (4)
Blood Coagulation Disorders, Inherited (156) · Coagulation Protein Disorders (156) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (156) · Genetic Diseases, Inborn (156) · Hemic and Lymphatic Diseases (156) · Hemorrhagic Disorders (156) · Blood Coagulation Disorders (155) · Hematologic Diseases (154) · Pathological Conditions, Signs and Symptoms (36) · Musculoskeletal Diseases (33) · Signs and Symptoms (20) · Neurologic Manifestations (19) · Pathologic Processes (18) · Genetic Diseases, X-Linked (17) · Cardiovascular Diseases (13)
Surveys and Questionnaires (7) · Factor VIII (6) · F8 protein, human (5) · Injections (5) · fitusiran (5) · Blood Specimen Collection (4) · Exercise (4) · Musculoskeletal Manipulations (4) · Ribavirin (4) · factor VIII-Fc fusion protein (4) · Blood Flow Restriction Therapy (3) · Factor VII (3) · Tranexamic Acid (3) · Aminocaproic Acid (2) · BAX 855 (2)
Investigación en Hemofilia y Fisioterapia (13) · Tri-Service General Hospital (TSGH) (5) · American Thrombosis and Hemostasis Network (4) · Institute of Hematology & Blood Diseases Hospital, China (4) · Nantes University Hospital (4) · Staidson (Beijing) Biopharmaceuticals Co., Ltd (4) · Universidad Católica San Antonio de Murcia (4) · Bayer (3) · Centre Hospitalier Universitaire de Saint Etienne (3) · Genzyme, a Sanofi Company (3) · Hacettepe University (3) · Hasan Kalyoncu University (3) · Laboratoire français de Fractionnement et de Biotechnologies (3) · Necmettin Erbakan University (3) · Oregon Health and Science University (3)
United States (33) · Spain (27) · Turkey (Türkiye) (22) · China (18) · France (16) · Canada (12) · Taiwan (10) · Italy (9) · United Kingdom (9) · Belgium (5) · India (5) · South Africa (5) · South Korea (5) · Sweden (5) · Brazil (4)
Lei Zhang, Ph.D (3) · Andrea Doria, MD (2) · Adam Wright, PhD (1) · Ahmet Fayik Oner, Prof. (1) · Alberto M Heredia-Rizo, PhD (1) · Alexandra Ruan, MD (1) · Alok Srivastava, MD (1) · Alshimaa Azab, PhD (1) · Andre M Assis, MD, PhD (1)
PMID 36796484, PMID 41637644, PMID 10960937, PMID 15374882, PMID 17058240, PMID 17090654, PMID 19039041, PMID 19127265, PMID 21337125, PMID 22149959, PMID 22215056, PMID 22765835, PMID 22785085, PMID 23855900, PMID 23863832, PMID 24099878, PMID 24509327, PMID 24614374, PMID 24949994, PMID 26039810, PMID 26346645, PMID 26613579, PMID 26926644, PMID 27392538, PMID 27522443, PMID 28137820, PMID 28290120, PMID 28779462, PMID 29084742, PMID 29224506, PMID 29271816, PMID 29435949, PMID 29497561, PMID 29677389, PMID 30093520, PMID 30328141, PMID 30338508, PMID 30790601, PMID 31011710, PMID 31317556, PMID 31326830, PMID 31548185, PMID 31814149, PMID 31917842, PMID 32324313, PMID 32492157, PMID 32497307, PMID 32734929, PMID 32744769, PMID 32842170
2018 (2), 2016 (1), 2019 (1), 2023 (1), 2025 (1), R01AI049508 (1), R34HL109334 (1)