8 completed, 5 recruiting, 4 unknown, 2 active not recruiting. 11 Not applicable, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 3, Recruiting 3, Unknown 2, Active not recruiting 1, Not yet recruiting 1, Terminated 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Heat Stroke: new trials by email Literature Review of Heat Stroke trials Research Report on Heat Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rapid Cool: Heat Stroke Treatment Recirculated water, Phoenix protocol - Hyperthermia | Not applicable | Not yet recruiting | State University of New York at Buffalo | 20 | 2026-09-21 | 2026-08-04 |
| Development of an Active Heat Dissipation Device Based on Thermoelectric Cooling Technology: Aiming to Improve Endurance Sports Performance TEC Vest, No Pre-Cooling (Without Vest), Water Cooled Vest - Heat Stroke | Not applicable | Active not recruiting | Kaohsiung Medical University | 30 | 2026-02-01 | 2026-04-20 |
| Genetic Risk Factor for Heat Stroke Heat Challenge - Carrier State, Heat Stroke | Recruiting | University of Iowa | 200 | 2025-11-19 | 2026-04-27 | |
| Mechanism Study of G Protein-coupled Receptor 81 in Multiple Organ Dysfunction of Heat Stroke Heat Stroke | Active not recruiting | Second Affiliated Hospital of Wenzhou Medical University | 100 | 2025-11-01 | 2026-05-29 | |
| Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Heat Stroke Peripheral blood test - Heat Stroke, Early Waking | Not yet recruiting | Xijing Hospital | 150 | 2025-08-31 | 2025-08-14 | |
| Beat the Heat Boston Air Conditioner, Electricity subsidy - Hot Weather; Adverse Effect, Heat Effect | Not applicable | Recruiting | Harvard School of Public Health (HSPH) | 100 | 2025-05-19 | 2026-01-22 |
| Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients the early in-hospital temperature management protocol for heat stroke patients - Heat Stroke | Not applicable | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 188 | 2024-07-01 | 2026-05-27 |
| Use of Sodium Bicarbonate as Prophylaxis for Kidney Damage in Patients With Heatstroke Sodium bicarbonate, No intervention - Heat Stroke, Acute Kidney Injury | Not applicable | Unknown | Hospital General de Mexicali | 1 | 2024-05-01 | 2024-10-02 |
| Heat Strain Prevention in Elderly Agricultural Workers Sustainable Heat Strain Prevention Program for Agricultural Elderly Workers (SHiP-AEW) - Heat Stress Disorders, Heat Stroke | Not applicable | Unknown | Cairo University | 120 | 2024-01-10 | 2024-04-23 |
| Non-inferiority Study of the Effect of Non-cooling Blanket on Body Temperature in Patients With Heat Stroke cooling blanket, non-cooling blanket - Heat Stroke | Not applicable | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 126 | 2023-05-28 | 2026-05-27 |
| Early Body Temperature Targets and Relationship With Prognosis in Patients With Heat Stroke observation - Heat Stroke | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 100 | 2023-05-28 | 2024-09-20 | |
| The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Heat Stroke Normal Saline infusion and Ringer lactate infusion - Heat Stroke | Not applicable | Terminated | Second Affiliated Hospital, Zhejiang University, School of Medicine | 104 | 2023-05-28 | 2026-06-04 |
| Study of Thermoregulation in Exercise Heat Stroke in the Military Environment Bike stress test, Heat Tolerance Test, Heat nociception test - Heat Stroke | Recruiting | Direction Centrale du Service de Santé des Armées | 50 | 2023-05-09 | 2023-08-02 | |
| Thermoregulatory Reactions of Medical Workers Who Use Personal Protective Equipment From Biological Hazards Personal protective equipment from biological hazard - Overheating | Completed | Federal State Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health" | 25 | 2021-03-29 | 2021-10-25 | |
| Study of Risk Factors for the Occurrence and Severity of Exertional Heatstroke in the Military Environment Saliva collection, Questionnaires, Ingestible core temperature capsule intake - Heat Stroke | Unknown | Direction Centrale du Service de Santé des Armées | 300 | 2020-11-02 | 2021-03-09 | |
| Aspirin as a Pre-Treatment for Exercise in Multiple Sclerosis Acetylsalicylic acid at 1st visit, then Placebo at 2nd visit, Placebo at 1st visit, then Acetylsalicylic acid at 2nd visit - Fatigue, Overheating | Early Phase 1 | Completed | Columbia University | 12 | 2017-01-13 | 2018-11-20 |
| Heat Emergency Awareness and Treatment (HEAT) Implementation of Community-based Home Heat Bundle, Regular Community Healthcare provision - Heat Illness, Heat Stroke | Not applicable | Completed | Johns Hopkins University | 16973 | 2016-11-30 | 2019-01-09 |
| Efficacy and Safety of Ryanodex® (EGL-4104) as Adjuvant Treatment in Subjects With Exertional Heat Stroke (EHS) Dantrolene sodium for injectable suspension - Heat Stroke | Phase 2 | Completed | Eagle Pharmaceuticals, Inc. | 34 | 2015-09-01 | 2021-06-29 |
| Comparing Risk of Heat Illness Based on Peak Core Temps During Preseason Football Camp Across 3 Different Age Levels Exertional Heat Illness, Hydration Status | Completed | University of Minnesota | 22 | 2013-07-01 | 2013-10-01 | |
| Chemical Ice Packs for Cooling Hyperthermic Patients Chemical Cold Pack - Heat Stroke, Heat Exhaustion | Not applicable | Completed | Stanford University | 8 | 2012-08-01 | 2018-11-26 |
Showing 20 of 22. Sign in to see all of them.
Heat Exhaustion (4) · Heat Stress Disorders (4) · Motor Activity (3) · Sunstroke (3) · Acute Kidney Injury (2) · COVID-19 (1) · Cigarette Smoking (1) · Dehydration (1) · Fatigue (1) · Hyperthermia (1) · Multiple Organ Failure (1) · Sleep Initiation and Maintenance Disorders (1) · Smoking (1)
Wounds and Injuries (22) · Heat Stress Disorders (18) · Pathological Conditions, Signs and Symptoms (4) · Behavior (3) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Pathologic Processes (2) · Renal Insufficiency (2) · Signs and Symptoms (2) · Urogenital Diseases (2) · Urologic Diseases (2) · Body Temperature Changes (1)
Aspirin (1) · Control Groups (1) · Dantrolene (1) · Exercise (1) · Nicotine (1) · Observation (1) · Ringer's Lactate (1) · Sodium Bicarbonate (1) · Surveys and Questionnaires (1)
Second Affiliated Hospital, Zhejiang University, School of Medicine (4) · Direction Centrale du Service de Santé des Armées (2) · Sheba Medical Center (2) · Cairo University (1) · Columbia University (1) · Eagle Pharmaceuticals, Inc. (1) · Federal State Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health" (1) · Harvard School of Public Health (HSPH) (1) · Hospital General de Mexicali (1) · Johns Hopkins University (1) · Kaohsiung Medical University (1) · Second Affiliated Hospital of Wenzhou Medical University (1) · Stanford University (1) · State University of New York at Buffalo (1) · University of Iowa (1)
China (6) · United States (4) · France (2) · Israel (2) · Egypt (1) · Mexico (1) · Pakistan (1) · Russia (1) · Saudi Arabia (1) · Taiwan (1)
Lan Chen (2) · Aaron Miller, PhD (1) · Adrian Hepner, MD (1) · Alexey Konyukhov (1) · Amit Druyan, M.D (1) · Amit Druyan, MD (1) · Austin R Krohn, MD (1) · Hiram J Jaramillo Ramirez, MD (1) · Junaid A Razzak, MD PhD (1) · Lan Chen, PHD (1) · Victoria Leavitt, PhD (1) · Yanyan Jia (1) · Yoram Epstein, PhD (1)
PMID 12075060, PMID 25771030, PMID 35101860, PMID 38838403
P20TW013028 (1)