56 completed, 22 recruiting, 12 unknown, 10 terminated. 27 Not applicable, 18 Phase 4, 16 Phase 2, 8 Phase 3, 3 Phase 1.
Follow this condition Literature Review of Heart Transplantation trials Research Report on Heart Transplantation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TORCH-LATAM-002: Regional Pathway for Adult Heart Transplant Evaluation and Candidacy TORCH Adult Heart Transplant Evaluation and Candidacy Pathway - Advanced Heart Failure, Heart Transplantation | Not applicable | Not yet recruiting | CardioVision International Tech, S.A.S. de C.V. | 360 | 2027-03-30 | 2026-10-13 |
| TORCH-LATAM-004: Regional Advanced-Therapy Pathways for Adults With Acquired or Structural Heart Disease TORCH Adult Advanced Therapies Pathway (TORCH-AATP) - Advanced Heart Failure, Acquired Heart Disease | Not applicable | Not yet recruiting | CardioVision International Tech, S.A.S. de C.V. | 360 | 2027-03-30 | 2026-10-13 |
| TORCH-LATAM-003: Regional Advanced-Therapy Pathways for Congenital Heart Disease TORCH Congenital Advanced Therapies Pathway (TORCH-CATP) - Congenital Heart Disease, Advanced Heart Failure | Not applicable | Not yet recruiting | CardioVision International Tech, S.A.S. de C.V. | 360 | 2027-03-30 | 2026-10-13 |
| Donor Derived Cell Free DNA (Dd-cfDNA) as a Biomarker for Allograft Rejection in Heart Transplant Recipients Donor-derived cell free DNA - Heart Transplantation | Enrolling by invitation | University of Aarhus | 100 | 2026-09-01 | 2026-10-21 | |
| Precise Cooler for Donor Heart Transport Organ transport using SherpaPak, Ryobi cooler for Organ Transport - Heart Transplantation | Not applicable | Not yet recruiting | Cedars-Sinai Medical Center | 80 | 2026-04-01 | 2026-03-18 |
| Multimodal Analysis of Endomyocardial Biopsies Heart Transplantation, Dilated Cardiomyopathy (DCM) | Recruiting | University Hospital, Essen | 216 | 2025-10-27 | 2026-01-22 | |
| Long-term Follow-up of the Offspring Born to Mothers With a Solid Organ Transplant, Transplantlines Next Generation Solid Organ Transplantation, Pregnancy | Recruiting | University Medical Center Groningen | 200 | 2025-10-15 | 2025-12-18 | |
| Cardiac REhabilitation COhort at the Medicine Campus DaVos to invEstigate Recovery Cardiac Rehabilitation, Heart Failure | Recruiting | Hochgebirgsklinik Davos | 10000 | 2025-08-05 | 2026-09-29 | |
| METABolic Deterioration in HTX Determines Outcomes Heart Transplantation | Recruiting | Heinrich-Heine University, Duesseldorf | 270 | 2025-07-24 | 2026-01-28 | |
| ZeroHeart Biopsy - Prediction of Deceased Donor Heart Transplant Performance From Organ Donors Using Pre-Transplant Biopsies - A Pilot Study Time Zero Donor Heart Biopsy for Molecular Analysis - Heart Transplantation, Graft Rejection | Recruiting | Medical University of Vienna | 50 | 2025-05-12 | 2025-05-21 | |
| A National Swedish Study Evaluating Dd-cfDNA for as a Diagnostic Biomarker for Rejection Surveillence in Heart Transplantation dd-cfDNA - Heart Transplantation, Heart Transplant Rejection | Recruiting | Karolinska Institutet | 120 | 2025-02-01 | 2026-04-15 | |
| Use of Machine-learning Algorithms, Biomarkers and Measures of Quality of Life to Personalize Medical Management of Liver and Heart Transplant Recipients Artificial Intelligence (AI), Hepatocellular Carcinoma (HCC) | Not yet recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 1000 | 2025-01-30 | 2025-01-14 | |
| Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease Exercise cardiac MRI Assessment, Cardiopulmonary Exercise Test - Pediatric ALL, Congenital Heart Disease | Recruiting | University of Alberta | 20 | 2025-01-20 | 2026-03-16 | |
| CARdiac Imaging and BIomarkers in the Diagnosis of Antibody Mediated Rejection in Heart Transplantation Heart Transplantation, Rejection Heart Transplant | Recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 683 | 2024-11-07 | 2026-05-22 | |
| Quantiferon CMV to Identify Treatment Need for Asymptomatic CMV Infection After Solid Organ Transplant (QUANTIFOT) Quantiferon CMV (assay that determine the presence of CMV-specific T lymphocytes)., Communication of the result of the QF-CMV to the clinician in charge - Cytomegalovirus Infections, Heart Transplantation | Not applicable | Recruiting | University Hospital, Grenoble | 288 | 2024-09-24 | 2024-10-01 |
| Preventive Catheter Ablation for Ventricular arrhythmiaS in Patients With End-sTage Heart faiLure Catheter ablation, Medical therapy - Heart Failure, Arrhythmia, Ventricular | Not applicable | Recruiting | Heart and Diabetes Center North-Rhine Westfalia | 160 | 2024-09-13 | 2024-12-04 |
| Genomics in Heart Transplants Heart Transplantation | Not yet recruiting | Heinrich-Heine University, Duesseldorf | 200 | 2024-01-01 | 2023-08-25 | |
| Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation Sodium chloride solution 3,5%, Sodium chloride solution 0,9% - Heart Transplantation, Acute Kidney Injury | Phase 2 | Recruiting | Fernando Bacal | 74 | 2023-11-08 | 2026-05-06 |
| First Clinical Evaluation of Heart Transplantation With Grafts Preserved Using an Ex-vivo Extended Perfusion System Heart transplantation - Heart Transplantation | Not applicable | Active not recruiting | Assistance Publique - Hôpitaux de Paris | 20 | 2023-10-28 | 2026-03-19 |
| Donor Circadian Rhythm and Its Correlation With Prognosis After Heart Transplantation Heart Transplantation, End-stage Heart Failure | Completed | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 200 | 2023-10-01 | 2025-12-24 |
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Heart Failure (13) · Cardiomyopathy, Hypertrophic (3) · Heart Defects, Congenital (3) · Heart Diseases (3) · Kidney Diseases (3) · Renal Insufficiency, Chronic (3) · Acute Kidney Injury (2) · Amyloid Neuropathies, Familial (2) · Arrhythmias, Cardiac (2) · Cardiomyopathies (2) · Cardiomyopathy, Dilated (2) · Coronary Artery Disease (2) · Cytomegalovirus Infections (2) · Motor Activity (2) · Rejection, Psychology (2)
Cardiovascular Diseases (23) · Heart Diseases (18) · Pathological Conditions, Signs and Symptoms (10) · Female Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (9) · Male Urogenital Diseases (9) · Pathologic Processes (9) · Urogenital Diseases (9) · Urologic Diseases (9) · Vascular Diseases (8) · Behavior (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Kidney Diseases (6) · Renal Insufficiency (5) · Congenital Abnormalities (4)
Mycophenolic Acid (14) · Cyclosporine (10) · Tacrolimus (10) · Everolimus (8) · Adrenal Cortex Hormones (5) · Antilymphocyte Serum (2) · Bortezomib (2) · Bradykinin (2) · Daclizumab (2) · Exercise (2) · Heart Transplantation (2) · Methylprednisolone (2) · Plasmapheresis (2) · Prednisone (2) · Surveys and Questionnaires (2)
Novartis Pharmaceuticals (6) · Astellas Pharma Europe Ltd. (5) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (5) · Cedars-Sinai Medical Center (4) · Hannover Medical School (4) · Hoffmann-La Roche (4) · CardioVision International Tech, S.A.S. de C.V. (3) · Heinrich-Heine University, Duesseldorf (3) · National Taiwan University Hospital (3) · University of Bologna (3) · Assistance Publique - Hôpitaux de Paris (2) · Astellas Pharma Inc (2) · Central Hospital, Nancy, France (2) · Heart and Diabetes Center North-Rhine Westfalia (2) · Mayo Clinic (2)
United States (32) · Germany (22) · France (17) · Italy (16) · Canada (9) · Spain (9) · Belgium (8) · United Kingdom (8) · Austria (7) · Norway (6) · Poland (6) · Sweden (6) · Australia (5) · Brazil (4) · Czechia (4)
Angelo Branzi, MD (2) · Christoph Bara, Dr. med. (2) · Luciano G Potena, MD (2) · Luciano Potena, MD (2) · Malte Kelm, Prof. (2) · Roberto Corti, MD (2) · Abraham Shaked, MD, PhD (1) · Aldona Browarek, MD, PhD (1)
PMID 15466273, PMID 16297770, PMID 19744284, PMID 19755203, PMID 19857702, PMID 19857703, PMID 19950084, PMID 20200265, PMID 20677285, PMID 21555100, PMID 22295178, PMID 22659939, PMID 22900793, PMID 23024190, PMID 23185084, PMID 23369437, PMID 23454241, PMID 23710539, PMID 23953553, PMID 24320690, PMID 25209092, PMID 25242802, PMID 26227088, PMID 26515686, PMID 26612581, PMID 27773449, PMID 27938912, PMID 28218407, PMID 28624338, PMID 28880921, PMID 29205855, PMID 29225901, PMID 29231747, PMID 29754400, PMID 29796417, PMID 29982668, PMID 30178515, PMID 30248148, PMID 30591285, PMID 30598488, PMID 30665258, PMID 30674290, PMID 32126998, PMID 32363949, PMID 32518655, PMID 33435695, PMID 33657039, PMID 35331039, PMID 35651624, PMID 35992748
2009 (2), 2005 (1), 2016 (1), 2018 (1), P20RR020643 (1), P50HL074732 (1), TL1TR002533 (1), U01AI063594 (1), UL1TR002535 (1)