4 terminated, 3 completed, 3 unknown, 2 recruiting. 13 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Terminated 4, Completed 3, Unknown 3, Recruiting 2, Not yet recruiting 1 |
Follow Granulomatosis with Polyangiitis: new trials by email Literature Review of Granulomatosis with Polyangiitis trials Research Report on Granulomatosis with Polyangiitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases Dengue 1,2,3,4 (attenuated) vaccine - Rheumatoid Arthritis (RA), Juvenile Idiopathic Arthritis (JIA) | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 477 | 2026-03-16 | 2026-07-20 |
| Comparison of a Strategy Based on Clinico-biological Monitoring Versus Pre-emptive Rituximab Treatment in Cases of ANCA Reappearance in Granulomatosis With Polyangiitis and Microscopic Polyangiitis. Rituximab - ANCA Associated Vasculitis (AAV), Polyangiitis (GPA) | Phase 4 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 70 | 2026-02-01 | 2026-03-05 |
| Avacopan vs Reduced-dose Glucocorticoids in ANCA-associated Vasculitis Avacopan, prednisolone and rituximab, Prednisolone and rituximab - ANCA Associated Vasculitis (AAV) | Phase 4 | Recruiting | Chiba University | 160 | 2024-11-15 | 2025-05-04 |
| Comparison of Tofacitinib and Methotrexate in the Maintained Treatment of GPA Tofacitinib, Methotrexate - Granulomatosis With Polyangiitis | Phase 4 | Unknown | Shanghai Zhongshan Hospital | 66 | 2021-07-01 | 2021-07-09 |
| Hydroxychloroquine in ANCA Vasculitis Evaluation Hydroxychloroquine, Placebo - ANCA Associated Vasculitis, Microscopic Polyangiitis | Phase 4 | Terminated | Guy's and St Thomas' NHS Foundation Trust | 43 | 2020-12-17 | 2026-04-29 |
| Rituximab for the Otolaryngologic Manifestations of Granulomatosis With Polyangiitis Rituximab, Placebo - Granulomatosis With Polyangiitis (Wegener's Granulomatosis) | Phase 4 | Terminated | Hospital for Special Surgery, New York | 3 | 2015-12-01 | 2018-03-22 |
| A Study Evaluating the Safety and Efficacy of Rituximab in Combination With Glucocorticoids in Participants With Wegener's Granulomatosis or Microscopic Polyangitis Methylprednisolone, Prednisone, Rituximab - Wegener's Granulomatosis or Microscopic Polyangiitis | Phase 4 | Completed | Hoffmann-La Roche | 30 | 2015-07-06 | 2022-07-06 |
| Low-dose Glucocorticoid Vasculitis Induction Study Rituximab, Glucocorticoids - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Microscopic Polyangiitis | Phase 4 | Unknown | Chiba University | 140 | 2014-10-01 | 2021-01-27 |
| Pilot Study of Short-Course Glucocorticoids and Rituximab for Treatment of ANCA-Associated Vasculitis Glucocorticoids, Rituximab - Granulomatosis With Polyangiitis, Microscopic Polyangiitis | Phase 4 | Completed | Massachusetts General Hospital | 20 | 2014-06-01 | 2021-06-25 |
| Alemtuzumab for ANCA Associated Refractory Vasculitis Alemtuzumab - Vasculitis, Microscopic Polyangiitis | Phase 4 | Unknown | Cambridge University Hospitals NHS Foundation Trust | 24 | 2011-02-01 | 2011-07-29 |
| Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD") CryoSpray Ablation - Lung Diseases, Obstructive, Sarcoidosis | Phase 4 | Terminated | CSA Medical, Inc. | 5 | 2008-10-01 | 2015-08-18 |
| Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years prednisone, methylprednisolone,cyclophosphamides, Cyclophosphamide, Azathioprine,prednisone,methylprednisolone, Mycophenolate mofetil,methotrexate - Vasculitis, Wegener's Granulomatosis | Phase 4 | Completed | Assistance Publique - Hôpitaux de Paris | 108 | 2005-07-01 | 2011-09-12 |
| Prevention of Relapses in Proteinase 3 (PR3)-Anti-neutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis azathioprine - Vasculitis | Phase 4 | Terminated | University Medical Center Groningen | 131 | 2003-06-01 | 2018-12-13 |
Microscopic Polyangiitis (9) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (5) · Vasculitis (3) · Churg-Strauss Syndrome (2) · Antiphospholipid Syndrome (1) · Arthritis, Juvenile (1) · Arthritis, Psoriatic (1) · Arthritis, Rheumatoid (1) · Axial Spondyloarthritis (1) · Lung Diseases, Obstructive (1) · Lupus Erythematosus, Systemic (1) · Myositis (1) · Polyarteritis Nodosa (1) · Recurrent respiratory papillomatosis (1)
Autoimmune Diseases (13) · Cardiovascular Diseases (13) · Immune System Diseases (13) · Lung Diseases (13) · Lung Diseases, Interstitial (13) · Respiratory Tract Diseases (13) · Skin Diseases (13) · Skin Diseases, Vascular (13) · Skin and Connective Tissue Diseases (13) · Vascular Diseases (13) · Systemic Vasculitis (12) · Vasculitis (10) · Brain Diseases (9) · Central Nervous System Diseases (9) · Cerebral Small Vessel Diseases (9)
Rituximab (6) · Prednisone (3) · Azathioprine (2) · Glucocorticoids (2) · Methotrexate (2) · Methylprednisolone (2) · Prednisolone (2) · Alemtuzumab (1) · Cryoelectron Microscopy (1) · Cryosurgery (1) · Cryotherapy (1) · Cyclophosphamide (1) · Hydroxychloroquine (1) · Mycophenolic Acid (1) · Vaccines (1)
Assistance Publique - Hôpitaux de Paris (2) · Chiba University (2) · CSA Medical, Inc. (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Hoffmann-La Roche (1) · Hospital for Special Surgery, New York (1) · Massachusetts General Hospital (1) · Shanghai Zhongshan Hospital (1) · University Medical Center Groningen (1) · University of Sao Paulo General Hospital (1)
United States (3) · France (2) · Japan (2) · United Kingdom (2) · Brazil (1) · China (1) · India (1) · Netherlands (1)
Coen A Stegeman, MD, PhD (1) · David D'Cruz (1) · David RW Jayne, MD MRCP (1) · Hiroshi Nakajima, M.D., Ph.D (1) · John H Stone, MD (1) · Lindi Jiang, PhD (1) · Masayoshi Harigai, MD, PhD (1) · Michael Machuzak, M.D. (1) · Robert F Spiera, MD (1)
PMID 34061144, PMID 19054820, PMID 23045170, PMID 25693055, PMID 27242368, PMID 29247107, PMID 33164993, PMID 33596356, PMID 35110332, PMID 35110333, PMID 35365179, PMID 36927642, PMID 37024906, PMID 37734880, PMID 9041949
2009 (1), 2018 (1), 2025 (1)