28 completed, 8 unknown, 2 recruiting, 1 active not recruiting. 10 Not applicable, 6 Phase 2, 6 Phase 4, 3 Phase 1, 3 Phase 3.
Follow Glucosephosphate Dehydrogenase Deficiency: new trials by email Literature Review of Glucosephosphate Dehydrogenase Deficiency trials Research Report on Glucosephosphate Dehydrogenase Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| High-Dose Vitamin C in G6PDA and Pyruvate Kinase Deficiency: A Safety Study Vitamin C - Pyruvate Kinase Deficiency, Glucose 6 Phosphate Dehydrogenase Deficiency | Phase 1 | Not yet recruiting | University of Utah | 3 | 2026-07-15 | 2026-05-28 |
| The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect Hyperbilirubinemia Phototherapy, ursodeoxycholic acid (UDCA) - Hyperbilirubinemia, Neonatal Indirect | Not applicable | Recruiting | Tishreen University Hospital | 70 | 2025-06-26 | 2026-04-21 |
| Screening of Coexistence Between Sickle Cell Anaemia and G6PD Deficiency G6pd enzyme sickling test, G6PD enzyme and sickling test, G6PD enzyme and HPLC - Sickle Cell Disease and G6PD Deficiency | Unknown | Fatma Hussein Mahmoud | 100 | 2025-01-01 | 2024-09-26 | |
| Primaquine for Vivax Malaria in G6PD Intermediate and Deficient Cases. Patients with G6PD enzyme activities between 30 and <70% of the AMM will be treated with schizontocidal treatment plus high dose primaquine 1mg/kg/day for 7 days, Patients with G6PD enzyme activities <30% of the AMM will be treated with schizontocidal treatment plus 8 weekly primaquine (0.75mg/kg dose). - Vivax Malaria, G6PD Deficiency | Phase 4 | Recruiting | Menzies School of Health Research | 100 | 2024-05-17 | 2026-03-12 |
| Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia Revised case management package - Vivax Malaria, G6PD Deficiency | Not applicable | Completed | Menzies School of Health Research | 2999 | 2023-08-07 | 2026-01-15 |
| Short Course Primaquine for the Radical Cure of P. Vivax - Papua New Guinea Revised case management package - Vivax Malaria, G6PD Deficiency | Not applicable | Completed | Macfarlane Burnet Institute for Medical Research and Public Health Ltd | 794 | 2023-08-07 | 2026-09-02 |
| Use of Macrolides in Acute Chest Syndrome: A Multicenter Retrospective Study Sickle Cell Disease, Acute Chest Syndrome | Completed | Centre Hospitalier de Saint-Denis | 250 | 2023-06-01 | 2025-06-25 | |
| Effects of N-acetyl Cystein (NAC) Supplementation in G6PD Deficient Individuals After Acute Exercise N-acetyl cystein, Placebo - G6PD Deficiency | Early Phase 1 | Unknown | University of Thessaly | 12 | 2023-02-01 | 2022-01-05 |
| Oxidative Stress, Carbohydrate Metabolism Disorders and G6PD Deficiency Alpha-lipoic acid, Placebo - G6PD Deficiency, Carbohydrate Metabolism Disorder | Not applicable | Unknown | University of Thessaly | 40 | 2023-02-01 | 2023-01-04 |
| Baby Detect : Genomic Newborn Screening Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1 | Completed | Centre Hospitalier Universitaire de Liege | 6824 | 2022-09-01 | 2025-08-12 | |
| Operational Feasibility of Appropriate Plasmodium Vivax Radical Cure After G6PD Testing in Thailand Tafenoquine, Primaquine - Malaria, Vivax, G6PD Deficiency | Completed | Dr. Prayuth Sudathip | 187 | 2022-05-23 | 2023-10-26 | |
| G6PD Deficiency in Infarction Patients in Shaanxi Province G6PD gene deficiency - Cerebral Infarction, G6PD Deficiency | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 1000 | 2021-11-01 | 2022-04-29 | |
| Operational Feasibility of Appropriate Radical Cure of Plasmodium Vivax With Tafenoquine or Primaquine After Quantitative G6PD Testing in Brazil Tafenoquine, Primaquine - Malaria, Vivax, G6PD Deficiency | Unknown | Fundação de Medicina Tropical Dr. Heitor Vieira Dourado | 16000 | 2021-09-09 | 2023-06-13 | |
| Primaquine Enantiomers in G6PD Deficient Human Volunteers RPQ, SPQ, Placebo - G6PD Deficiency | Phase 1 | Completed | University of Mississippi, Oxford | 18 | 2020-09-01 | 2024-11-21 |
| Safety and Efficacy of Aspirin in Stroke Patients With Glucose-6-phosphate Dehydrogenase Deficiency (SAST) Aspirin, Clopidogrel - G6PD Deficiency, Stroke | Phase 4 | Unknown | First Affiliated Hospital, Sun Yat-Sen University | 440 | 2020-01-22 | 2022-03-16 |
| Comparative Evaluation of the FINDER Instrument and FINDER G6PD Cartridge in Adults and Neonates G6PD assay - G6PD, G6PD Deficiency | Completed | Baebies, Inc. | 119 | 2019-11-11 | 2020-11-23 | |
| Validation of a Diagnostic Test for Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in Anti-coagulated Blood SD Biosensor STANDARD G6PD Test, Pointe Scientific Test Kit, HemoCue System - G6PD Deficiency | Not applicable | Completed | PATH | 229 | 2019-08-12 | 2021-11-09 |
| Evaluation of a Diagnostic to Identify Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in Brazil SD Biosensor STANDARD G6PD Test, Pointe Scientific Test Kit, HemoCue System - G6PD Deficiency | Not applicable | Completed | PATH | 1754 | 2019-06-27 | 2021-11-11 |
| Validation of Diagnostics to Identify Glucose-6-phosphate Dehydrogenase Activity in the US SD Biosensor G6PD Analyzer, Pointe Scientific Test Kit, HemoCue System - G6PD Deficiency | Not applicable | Completed | PATH | 250 | 2019-05-13 | 2022-05-10 |
| Early Check: Expanded Screening in Newborns Confirmatory Testing - Spinal Muscular Atrophy, Fragile X Syndrome | Active not recruiting | RTI International | 30000 | 2018-10-15 | 2026-07-01 |
Showing 20 of 41. Sign in to see all of them.
Malaria, Vivax (8) · Malaria (6) · Anemia, Sickle Cell (5) · Hemolysis (4) · Cystic Fibrosis (3) · Hyperbilirubinemia, Neonatal (3) · 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (2) · Acidemia, isovaleric (2) · Anemia, Hemolytic (2) · Argininosuccinic Aciduria (2) · Ataxia with vitamin E deficiency (2) · Basal ganglia disease, biotin-responsive (2) · Beta ketothiolase deficiency (2) · Biotinidase Deficiency (2)
Anemia (41) · Anemia, Hemolytic, Congenital (41) · Carbohydrate Metabolism, Inborn Errors (41) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (41) · Genetic Diseases, Inborn (41) · Hemic and Lymphatic Diseases (41) · Metabolic Diseases (41) · Metabolism, Inborn Errors (41) · Nutritional and Metabolic Diseases (41) · Hematologic Diseases (40) · Anemia, Hemolytic (39) · Infections (16) · Mosquito-Borne Diseases (15) · Parasitic Diseases (15) · Protozoan Infections (15)
Primaquine (9) · Chloroquine (3) · tafenoquine (3) · Artemether, Lumefantrine Drug Combination (2) · Phototherapy (2) · Thioctic Acid (2) · tin mesoporphyrin (2) · Ascorbic Acid (1) · Aspirin (1) · Blood Cell Count (1) · Clopidogrel (1) · Drugs, Investigational (1) · Exercise (1) · Flow Cytometry (1) · Sodium Chloride (1)
PATH (6) · University of Thessaly (3) · Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (2) · London School of Hygiene and Tropical Medicine (2) · Menzies School of Health Research (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · University of Mississippi, Oxford (2) · Ain Shams University (1) · Allergan (1) · Baebies, Inc. (1) · Centre Hospitalier Universitaire de Liege (1) · Centre Hospitalier de Saint-Denis (1) · Columbia University (1) · Dr. Prayuth Sudathip (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1)
United States (14) · Brazil (4) · China (3) · Thailand (3) · Cambodia (2) · Greece (2) · Indonesia (2) · Papua New Guinea (2) · Belgium (1) · Burkina Faso (1) · Colombia (1) · Egypt (1) · Ethiopia (1) · France (1) · Mali (1)
Athanasios Z Jamurtas, PhD (3) · Marcus Lacerda, MD, PhD (2) · Rick M Fairhurst, M.D. (2) · Adnan H Dayoub, Prof.Neonat (1) · Ari Winasti Satyagraha, PhD (1) · Attallah Kappas (1) · Chalermpol Chalermpol, M.D. (1) · Chantana Padungtod, M.D., DrPH (1) · Cheryl Berne, MD (1) · Curt Scharfe, MD, PhD (1) · Dhelio Batista, MD, PhD (1) · Dysoley Lek, MD (1) · Francois Nosten, MD/PhD (1)
PMID 40670924, PMID 19075138, PMID 19858149, PMID 21666744, PMID 23071567, PMID 23349902, PMID 23448727, PMID 25049249, PMID 26687956, PMID 26701602, PMID 29324864, PMID 30871496, PMID 31315600, PMID 31534356, PMID 31961822, PMID 32179526, PMID 33682983, PMID 34238299, PMID 34383774, PMID 34389161, PMID 34871570, PMID 35142618, PMID 37027391, PMID 37909740, PMID 38365417, PMID 38452779, PMID 39785834, PMID 42326839