65 completed, 20 unknown, 14 recruiting, 8 withdrawn. 37 Not applicable, 21 Phase 2, 11 Phase 3, 7 Phase 1, 6 Phase 4.
Follow Hemolysis: new trials by email Literature Review of Hemolysis trials Research Report on Hemolysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders Ravulizumab - Preeclampsia | Phase 2 | Recruiting | Mayo Clinic | 14 | 2027-04-01 | 2026-10-22 |
| Pneumatic Tube System Versus Personnel Transport and the Hemolysis Index of Emergency Department Blood Samples: A Randomized, Split-Sample, Single-Blind Trial Pneumatic Tube System Transport, Manual Personnel Transport - Hemolysis, Diagnostic Errors | Not applicable | Recruiting | Marmara University Pendik Training and Research Hospital | 166 | 2026-09-01 | 2026-09-23 |
| A Study of Iptacopan in Korean Patients With Paroxysmal Nocturnal Hemoglobinuria or C3 Glomerulopathy Paroxysmal Nocturnal Hemoglobinuria, C3 Glomerulopathy | Recruiting | Novartis Pharmaceuticals | 21 | 2026-06-15 | 2026-06-26 | |
| Early vs. Late Tourniquet Release and Phlebotomy-Induced Hemolysis in the Emergency Department: TOURNI-ED Sphygmomanometer-Applied Venous Stasis with Varied Release Timing During Phlebotomy - Hemolysis, Blood Specimen Collection | Not applicable | Completed | Marmara University Pendik Training and Research Hospital | 792 | 2026-06-01 | 2026-08-27 |
| Comparison of Efficacy and Safety of Manual Syringing Versus Pneumatic Pressure Bag for Blood Transfusion in Patients Undergoing Cesarean Section With Major Obstetric Hemorrhage Manual syringing, pneumatic pressure bag - Obstetric Hemostasis, Intravascular Hemolysis | Not applicable | Recruiting | Aswan University | 50 | 2025-09-01 | 2026-03-12 |
| Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis Danicopan - Paroxysmal Nocturnal Hemoglobinuria, PNH | Phase 3 | Recruiting | Alexion Pharmaceuticals, Inc. | 6 | 2025-08-11 | 2025-12-23 |
| Feasibility Performance Study of ABL90 FLEX PLUS HEM The purpose of this study is to investigate the performance of the hemolysis detection function on the ABL90 FLEX PLUS HEM using arterial or venous whole blood - Hemolysis | Recruiting | Radiometer Medical ApS | 95 | 2025-08-04 | 2026-01-15 | |
| Modeling Blood Management and Hemolytic Risk in Pediatric Heart Surgery blood sampling - Heart Surgery, Blood Transfusion | Recruiting | Boston Children's Hospital | 50 | 2025-08-01 | 2026-01-07 | |
| Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury Non-pulsatile blood flow, Pulsatile blood flow - Acute Kidney Injury, Hemolysis | Not applicable | Recruiting | University of Colorado, Denver | 1100 | 2025-05-19 | 2025-05-21 |
| Ventilatory Functions and Physical Intolerance in ESRD Adolescents: Response to Program of Walking With Dogs incentive spirometer and walking with dog, training by incentive spirometer only - End Stage Renal Disease, Hemolysis | Not applicable | Recruiting | Cairo University | 40 | 2025-02-05 | 2025-03-06 |
| Relationship Between Biological Phenotype, Clinical Severity of Sickle Cell Disease, and Blood Coagulation blood sampling - Sickle Cell Disease (SCD) | Not yet recruiting | Hospices Civils de Lyon | 200 | 2025-02-01 | 2025-01-15 | |
| Restless Leg Syndrome: Is There a Response to Buddhist Walking Meditation in Hemodialysis Buddhist walking meditation - Hemolysis, Restless Legs Syndrome | Not applicable | Recruiting | Cairo University | 40 | 2024-11-06 | 2025-02-04 |
| Renal Function and Hemolysis After Pulsed-field Ablation for Atrial Fibrillation Pulsed-field ablation - Atrial Fibrillation | Unknown | Charles University, Czech Republic | 100 | 2024-05-01 | 2024-09-19 | |
| Warmed Blood Transfusion in Premature Infants Warmed Blood Transfusion - Transfusion Related Complication, Premature | Not applicable | Unknown | Goztepe Prof Dr Suleyman Yalcın City Hospital | 50 | 2024-04-01 | 2024-05-22 |
| A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders AMPD3, OMIM*102772, AMP Deaminase Deficiency, AK1, OMIM *103000, Adenylate Kinase Deficiency | Recruiting | National Human Genome Research Institute (NHGRI) | 999 | 2023-12-19 | 2026-08-19 | |
| Hemolysis During Pulsed-field and Radiofrequency Ablation Pulsed-field ablation, Radiofrequency ablation - Atrial Fibrillation, Hemolysis | Unknown | Charles University, Czech Republic | 60 | 2023-11-15 | 2023-11-15 | |
| Biodex Training in Hemodialysis Females With Osteopenia biodex training - Hemolysis | Not applicable | Unknown | Ahram Canadian University | 58 | 2023-11-08 | 2024-01-25 |
| Optimization of Prime Fluid Strategy to Preserve Microcirculatory Perfusion During Cardiac Surgery With Cardiopulmonary Bypass, Part II Treatment: additional albumin during cardiopulmonary bypass, control: additional ringers during cardiopulmonary bypass - Endothelial Dysfunction, Hemolysis | Not applicable | Unknown | Amsterdam UMC, location VUmc | 64 | 2023-10-15 | 2023-04-26 |
| Electric Polarization of Red Blood Cells : A Cohort Study to Assess the Erythrocytes Membrane Integrity Through Charge Conservation, Following Cardiac Surgery. Polarization of red blood cells - Inflammatory Response, Erythrocyte Destruction | Withdrawn | Anthea Hospital Bari | 2023-09-01 | 2024-07-30 | ||
| CPB Prime Fluid Strategies to Preserve Mcirocirculatory Perfusion A: gelofusine + ringers, B: albumine + ringers, C: ringers + retrograde autologous priming - Endothelial Dysfunction, Hemolysis | Not applicable | Completed | Amsterdam UMC, location VUmc | 48 | 2023-07-10 | 2025-03-27 |
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Anemia (20) · Hemoglobinuria, Paroxysmal (14) · Anemia, Sickle Cell (11) · Hematologic Diseases (11) · Anemia, Hemolytic (10) · Anemia, Hemolytic, Autoimmune (6) · Glucosephosphate Dehydrogenase Deficiency (4) · Hemoglobinopathies (4) · Hemoglobinuria (4) · Hepatitis C (4) · Kidney Failure, Chronic (4) · Renal Insufficiency (4) · Thalassemia (4) · Thrombocytopenia (4)
Pathological Conditions, Signs and Symptoms (117) · Pathologic Processes (115) · Hemic and Lymphatic Diseases (50) · Hematologic Diseases (39) · Anemia, Hemolytic (33) · Anemia (27) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (26) · Female Urogenital Diseases and Pregnancy Complications (23) · Urogenital Diseases (23) · Female Urogenital Diseases (18) · Male Urogenital Diseases (18) · Anemia, Hemolytic, Congenital (17) · Genetic Diseases, Inborn (17) · Signs and Symptoms (17) · Urologic Diseases (17)
Blood Specimen Collection (7) · Ribavirin (4) · Rituximab (4) · danicopan (4) · eculizumab (4) · Acetaminophen (3) · Primaquine (3) · pegcetacoplan (3) · peginterferon alfa-2a (3) · Nitric Oxide (2) · Phototherapy (2) · alpha-Tocopherol (2) · fludarabine (2) · iptacopan (2) · Alemtuzumab (1)
Alexion Pharmaceuticals, Inc. (6) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (5) · Apellis Pharmaceuticals, Inc. (3) · Assistance Publique - Hôpitaux de Paris (3) · National Heart, Lung, and Blood Institute (NHLBI) (3) · Novartis Pharmaceuticals (3) · AO GENERIUM (2) · Amsterdam UMC, location VUmc (2) · Assiut University (2) · Cairo University (2) · Charles University, Czech Republic (2) · Forma Therapeutics, Inc. (2) · Hospices Civils de Lyon (2) · Marmara University Pendik Training and Research Hospital (2) · Massachusetts General Hospital (2)
United States (36) · France (14) · Italy (10) · Canada (9) · Turkey (Türkiye) (9) · United Kingdom (9) · Spain (8) · China (7) · Egypt (7) · South Korea (6) · Brazil (5) · Germany (5) · Malaysia (5) · Netherlands (5) · Russia (5)
Federico Grossi, MD, PhD (3) · Ali MA Ismail, lecturer (2) · Geir E Tjonnfjord, MD, PhD (2) · Oksana A. Markova, MD (2) · Sigbjorn Berentsen, MD, PhD (2) · Alexander Roeth, MD (1) · Alexey Evtushenko, MD,PhD (1) · Anders Hallberg, MD-PhD (1) · Arjen Dondorp, MD (1) · Athanasios Z Jamurtas, Dr (1) · Bing Han, MD (1) · Bridget Barber, MBBS (1)
PMID 23273528, PMID 33933412, PMID 35647644, PMID 35869170, PMID 111670, PMID 11779730, PMID 15981230, PMID 16360171, PMID 16506966, PMID 17702897, PMID 19325491, PMID 20113454, PMID 20163377, PMID 20634373, PMID 20841509, PMID 20854821, PMID 21729098, PMID 21835904, PMID 22547579, PMID 22748193, PMID 23105782, PMID 23995229, PMID 25389409, PMID 25705899, PMID 25840802, PMID 25938131, PMID 26175690, PMID 26285072, PMID 27030156, PMID 27582423, PMID 27605222, PMID 28533306, PMID 28748536, PMID 29333256, PMID 29567027, PMID 29690924, PMID 30291112, PMID 30365961, PMID 30450553, PMID 30650326, PMID 30706521, PMID 32776545, PMID 33249569, PMID 33765419, PMID 34398258, PMID 35019238, PMID 35180298, PMID 35561315, PMID 35698835, PMID 35732155
2009 (2), 2019 (2), 2008 (1), 2014 (1), 2017 (1), K23HL145140 (1), K23HL151882 (1), R34HL108761 (1)