13 completed, 5 unknown, 1 active not recruiting, 1 recruiting. 7 Not applicable, 4 Phase 4, 1 Early Phase 1, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 6, Unknown 1 |
| Phase 4 | 4 | Completed 1, Recruiting 1, Terminated 1, Unknown 1 |
| Early Phase 1 | 1 | Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow G6PD Deficiency: new trials by email Literature Review of G6PD Deficiency trials Research Report on G6PD Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Primaquine for Vivax Malaria in G6PD Intermediate and Deficient Cases. Patients with G6PD enzyme activities between 30 and <70% of the AMM will be treated with schizontocidal treatment plus high dose primaquine 1mg/kg/day for 7 days, Patients with G6PD enzyme activities <30% of the AMM will be treated with schizontocidal treatment plus 8 weekly primaquine (0.75mg/kg dose). - Vivax Malaria, G6PD Deficiency | Phase 4 | Recruiting | Menzies School of Health Research | 100 | 2024-05-17 | 2026-03-12 |
| Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia Revised case management package - Vivax Malaria, G6PD Deficiency | Not applicable | Completed | Menzies School of Health Research | 2999 | 2023-08-07 | 2026-01-15 |
| Short Course Primaquine for the Radical Cure of P. Vivax - Papua New Guinea Revised case management package - Vivax Malaria, G6PD Deficiency | Not applicable | Completed | Macfarlane Burnet Institute for Medical Research and Public Health Ltd | 794 | 2023-08-07 | 2026-09-02 |
| Effects of N-acetyl Cystein (NAC) Supplementation in G6PD Deficient Individuals After Acute Exercise N-acetyl cystein, Placebo - G6PD Deficiency | Early Phase 1 | Unknown | University of Thessaly | 12 | 2023-02-01 | 2022-01-05 |
| Oxidative Stress, Carbohydrate Metabolism Disorders and G6PD Deficiency Alpha-lipoic acid, Placebo - G6PD Deficiency, Carbohydrate Metabolism Disorder | Not applicable | Unknown | University of Thessaly | 40 | 2023-02-01 | 2023-01-04 |
| Operational Feasibility of Appropriate Plasmodium Vivax Radical Cure After G6PD Testing in Thailand Tafenoquine, Primaquine - Malaria, Vivax, G6PD Deficiency | Completed | Dr. Prayuth Sudathip | 187 | 2022-05-23 | 2023-10-26 | |
| G6PD Deficiency in Infarction Patients in Shaanxi Province G6PD gene deficiency - Cerebral Infarction, G6PD Deficiency | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 1000 | 2021-11-01 | 2022-04-29 | |
| Operational Feasibility of Appropriate Radical Cure of Plasmodium Vivax With Tafenoquine or Primaquine After Quantitative G6PD Testing in Brazil Tafenoquine, Primaquine - Malaria, Vivax, G6PD Deficiency | Unknown | Fundação de Medicina Tropical Dr. Heitor Vieira Dourado | 16000 | 2021-09-09 | 2023-06-13 | |
| Primaquine Enantiomers in G6PD Deficient Human Volunteers RPQ, SPQ, Placebo - G6PD Deficiency | Phase 1 | Completed | University of Mississippi, Oxford | 18 | 2020-09-01 | 2024-11-21 |
| Safety and Efficacy of Aspirin in Stroke Patients With Glucose-6-phosphate Dehydrogenase Deficiency (SAST) Aspirin, Clopidogrel - G6PD Deficiency, Stroke | Phase 4 | Unknown | First Affiliated Hospital, Sun Yat-Sen University | 440 | 2020-01-22 | 2022-03-16 |
| Comparative Evaluation of the FINDER Instrument and FINDER G6PD Cartridge in Adults and Neonates G6PD assay - G6PD, G6PD Deficiency | Completed | Baebies, Inc. | 119 | 2019-11-11 | 2020-11-23 | |
| Validation of a Diagnostic Test for Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in Anti-coagulated Blood SD Biosensor STANDARD G6PD Test, Pointe Scientific Test Kit, HemoCue System - G6PD Deficiency | Not applicable | Completed | PATH | 229 | 2019-08-12 | 2021-11-09 |
| Evaluation of a Diagnostic to Identify Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in Brazil SD Biosensor STANDARD G6PD Test, Pointe Scientific Test Kit, HemoCue System - G6PD Deficiency | Not applicable | Completed | PATH | 1754 | 2019-06-27 | 2021-11-11 |
| Validation of Diagnostics to Identify Glucose-6-phosphate Dehydrogenase Activity in the US SD Biosensor G6PD Analyzer, Pointe Scientific Test Kit, HemoCue System - G6PD Deficiency | Not applicable | Completed | PATH | 250 | 2019-05-13 | 2022-05-10 |
| Early Check: Expanded Screening in Newborns Confirmatory Testing - Spinal Muscular Atrophy, Fragile X Syndrome | Active not recruiting | RTI International | 30000 | 2018-10-15 | 2026-07-01 | |
| Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients Chloroquine, Primaquine - Vivax Malaria, G6PD Deficiency | Phase 2 | Completed | Fundação de Medicina Tropical Dr. Heitor Vieira Dourado | 106 | 2018-07-20 | 2025-02-20 |
| Assessing a Risk Model for G6PD Deficiency primaquine, chloroquine + primaquine - Malaria, Vivax, G6PD Deficiency | Phase 4 | Terminated | PATH | 54 | 2018-05-07 | 2021-11-12 |
| Effects of Alpha Lipoic Acid Supplementation in G6PD Deficient Individuals After Acute Exercise Alpha-lipoic acid, Placebo - G6PD Deficiency | Not applicable | Completed | University of Thessaly | 10 | 2016-12-01 | 2017-11-06 |
| Safety and Tolerability of Low Dose Primaquine Dihydroartemisinin piperaquine (DHA PP), Primaquine - Malaria, Falciparum, G6PD Deficiency | Phase 4 | Completed | Malaria Consortium | 109 | 2014-10-01 | 2016-08-23 |
| At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions All Diagnosed Health Conditions, ADD/ADHD | Completed | Sanguine Biosciences | 17667 | 2013-07-01 | 2024-04-18 |
Showing 20 of 21. Sign in to see all of them.
Glucosephosphate Dehydrogenase Deficiency (21) · Malaria, Vivax (7) · Anemia, Sickle Cell (2) · Cystic Fibrosis (2) · Diabetes Mellitus (2) · Epilepsy (2) · Hemolysis (2) · Muscular Atrophy, Spinal (2) · Muscular Dystrophy, Duchenne (2) · beta-Thalassemia (2) · 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (1) · 3-Hydroxyacyl-CoA Dehydrogenase Deficiency (1) · 3-methylcrotonyl CoA carboxylase 1 deficiency (1) · 3-methylcrotonyl CoA carboxylase 2 deficiency (1) · Acidemia, isovaleric (1)
Anemia (21) · Anemia, Hemolytic (21) · Anemia, Hemolytic, Congenital (21) · Carbohydrate Metabolism, Inborn Errors (21) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (21) · Genetic Diseases, Inborn (21) · Hematologic Diseases (21) · Hemic and Lymphatic Diseases (21) · Metabolic Diseases (21) · Metabolism, Inborn Errors (21) · Nutritional and Metabolic Diseases (21) · Infections (10) · Mosquito-Borne Diseases (9) · Parasitic Diseases (9) · Protozoan Infections (9)
Primaquine (6) · Chloroquine (2) · Thioctic Acid (2) · tafenoquine (2) · Aspirin (1) · Blood Cell Count (1) · Clopidogrel (1) · Exercise (1) · ethofenprox (1) · sodium chromate(VI) (1)
PATH (4) · University of Thessaly (3) · Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (2) · Menzies School of Health Research (2) · Baebies, Inc. (1) · Columbia University (1) · Dr. Prayuth Sudathip (1) · First Affiliated Hospital Xi'an Jiaotong University (1) · First Affiliated Hospital, Sun Yat-Sen University (1) · Macfarlane Burnet Institute for Medical Research and Public Health Ltd (1) · Malaria Consortium (1) · RTI International (1) · Sanguine Biosciences (1) · University of Mississippi, Oxford (1)
United States (7) · Brazil (4) · China (2) · Greece (2) · Papua New Guinea (2) · Thailand (2) · Cambodia (1) · Ethiopia (1) · Indonesia (1)
Athanasios Z Jamurtas, PhD (3) · Marcus Lacerda, MD, PhD (2) · Chalermpol Chalermpol, M.D. (1) · Chantana Padungtod, M.D., DrPH (1) · Cheryl Berne, MD (1) · Curt Scharfe, MD, PhD (1) · Dhelio Batista, MD, PhD (1) · Dysoley Lek, MD (1) · Hongmei Cao, Professor (1) · Houman Hemmati, MD (1) · James Kublin, MD, MPH (1) · Jinsheng Zeng, MD,PhD (1) · Larry Walker, Ph.D. (1) · Leanne Robinson, Prof (1)
PMID 40670924, PMID 30871496, PMID 31315600, PMID 31961822, PMID 32179526, PMID 34238299, PMID 34383774, PMID 34389161, PMID 35142618, PMID 38365417, PMID 38452779, PMID 39785834, PMID 42326839