8 completed, 2 unknown. 10 Phase 2, 3 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 8, Unknown 2 |
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 1, Unknown 1 |
Follow Eye Hemorrhage: new trials by email Literature Review of Eye Hemorrhage trials Research Report on Eye Hemorrhage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anti-VEGF vs. Prompt Vitrectomy for VH From PDR 2-mg Intravitreous Aflibercept Injection, Prompt Vitrectomy Plus Panretinal Photocoagulation - Proliferative Diabetic Retinopathy, Vitreous Hemorrhage | Phase 2 / Phase 3 | Completed | Jaeb Center for Health Research | 205 | 2016-11-01 | 2021-04-20 |
| Endolaserless Vitrectomy With Intravitreal IAI for PDR-Related VH Aflibercept, Endolaserless Vitrectomy - Proliferative Diabetic Retinopathy | Phase 1 / Phase 2 | Unknown | Southeast Retina Center, Georgia | 24 | 2016-06-01 | 2016-11-29 |
| Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular AMD Ranibizumab, C3F8 Gas, tPA - Exudative Macular Degeneration, Retinal Hemorrhage | Phase 2 / Phase 3 | Completed | King's College Hospital NHS Trust | 55 | 2014-09-01 | 2020-07-14 |
| Aflibercept Injection for Proliferative Diabetic Retinopathy Intravitreal Aflibercept Injection, Standard Vitrectomy - Vitreous Hemorrhage | Phase 2 | Completed | University of Oklahoma | 12 | 2013-03-01 | 2023-12-27 |
| Intravitreal Ozurdex After Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy Intravitreal dexamethasone implant, Vitrectomy - Proliferative Diabetic Retinopathy | Phase 2 | Completed | Anders Kvanta | 100 | 2011-11-01 | 2024-01-30 |
| Intravitreal Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy (N) Ranibizumab, Saline - Vitreous Hemorrhage, Proliferative Diabetic Retinopathy | Phase 2 / Phase 3 | Completed | Jaeb Center for Health Research | 261 | 2010-06-01 | 2016-08-26 |
| Adjuvant Intravitreal Bevacizumab in Pars Plana Vitrectomy for Vitreous Hemorrhage Bevacizumab, bevacizumab - Vitreous Hemorrhage Secondary to PDR | Phase 2 | Unknown | University of Sao Paulo | 1 | 2010-01-01 | 2010-03-24 |
| Ranibizumab for Diabetic Traction Retinal Detachment Ranibizumab, Sham injection - Diabetic Retinopathy, Retinal Detachment | Phase 2 | Completed | University of Sao Paulo | 19 | 2008-12-01 | 2010-09-14 |
| Pars Plana Vitrectomy (PPV) Versus Preoperative Intravitreal Bevacizumab Plus PPV to Treat Diabetic Tractional Retinal Detachment (IBETRA) Bevacizumab, pars plana vitrectomy - Diabetic Retinopathy, Retinal Detachment | Phase 2 | Completed | University of Sao Paulo | 20 | 2008-03-01 | 2008-06-05 |
| Preoperative Bevacizumab for Vitreous Hemorrhage bevacizumab, pars plana vitrectomy - Diabetic Retinopathy, Vitreous Hemorrhage | Phase 1 / Phase 2 | Completed | University of Sao Paulo | 16 | 2007-11-01 | 2008-10-03 |
Vitreous Hemorrhage (9) · Diabetic Retinopathy (3) · Retinal Detachment (2) · Diabetes Mellitus (1) · Hemorrhage (1) · Macular Degeneration (1) · Retinal Diseases (1) · Retinal Hemorrhage (1) · Wet Macular Degeneration (1)
Eye Diseases (10) · Pathologic Processes (10) · Pathological Conditions, Signs and Symptoms (10) · Hemorrhage (9) · Endocrine System Diseases (4) · Retinal Diseases (4) · Cardiovascular Diseases (3) · Diabetes Complications (3) · Diabetes Mellitus (3) · Diabetic Angiopathies (3) · Vascular Diseases (3) · Glucose Metabolism Disorders (1) · Metabolic Diseases (1) · Nutritional and Metabolic Diseases (1)
Bevacizumab (3) · Ranibizumab (3) · aflibercept (3) · Calcium Dobesilate (1) · Dexamethasone (1) · Intravitreal Injections (1) · Sodium Chloride (1) · Tissue Plasminogen Activator (1) · Vitrectomy (1) · perflutren (1) · salicylhydroxamic acid (1)
University of Sao Paulo (4) · Jaeb Center for Health Research (2) · Anders Kvanta (1) · King's College Hospital NHS Trust (1) · Southeast Retina Center, Georgia (1) · University of Oklahoma (1)
Brazil (4) · United States (4) · Canada (1) · Sweden (1) · United Kingdom (1)
Abdhish Bhavsar, MD (1) · Adam R. Glassman, MS (1) · Anders Kvanta, PhD (1) · Andrew Antoszyk, MD (1) · Daniel R Lucena, MD (1) · Dennis M Marcus, MD (1) · Felipe Almeida, MD (1) · Robert E Leonard, MD (1) · Rodrigo Jorge, MD, PhD (1) · Timothy L Jackson, PhD,FRCOpht (1) · Vinay A Shah, MD (1)
PMID 37260074, PMID 19208678, PMID 23370902, PMID 33320223, PMID 33956075, PMID 37972038, PMID 39418015
U10EY014231 (1), U10EY018817 (1)