26 completed, 9 unknown, 6 recruiting, 2 active not recruiting. 12 Phase 4, 11 Not applicable, 9 Phase 3, 6 Phase 1, 6 Phase 2.
Follow this drug Literature Review of Somatostatin trials Research Report on Somatostatin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Terlipressin vs. Somatostatin in Cirrhotic Patients With Acute Variceal Bleeding and Renal Dysfunction 2-4 mg of terlipressin, 3 mg of somatostatin - Liver Cirrhosis | Not applicable | Not yet recruiting | General Hospital of Shenyang Military Region | 64 | 2026-09-25 | 2026-08-27 |
| Effects of Terlipressin and Somatostatin on Portal Pressure in Patients Undergoing Living Donor Liver Transplantation Somatostatin, Terlipressin - Liver Transplantation, Portal Hypertension | Not applicable | Recruiting | Istanbul Medipol University Hospital | 50 | 2025-12-29 | 2026-04-29 |
| Somatostatin Plus Clear Liquid Diet Versus Diverting Stoma in Patients With Rectal Cancer Undergoing Ultra-Low Anterior Resection Somatostatin, Clear Liquid Diet, Prophylactic Diverting Stoma - Rectal Cancer, Anastomotic Leakage | Not applicable | Recruiting | Tongji Hospital | 72 | 2025-11-17 | 2026-05-26 |
| Measuring Amino Acid and Glucose Metabolism in Healthy Volunteers and NAFLD Patients Using Total-body PET 18F-FDG (oral), 18F-FDG (intravenous), 18F-FET (oral) - Glucose Metabolism, NAFLD (Nonalcoholic Fatty Liver Disease) | Not applicable | Active not recruiting | Copenhagen University Hospital, Rigshospitalet | 36 | 2024-11-05 | 2026-02-02 |
| Absorbed Tumor Dose in Peptide Receptor Radionuclide Therapy with Long-acting Somatostatin Analogues - ATSA Trial Somatostatin analog - Neuroendocrine Tumors, Neuroendocrine Tumor Grade 1 | Phase 2 / Phase 3 | Recruiting | The Netherlands Cancer Institute | 39 | 2024-06-25 | 2025-03-03 |
| Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation Somatostatin, Epinephrine - Obesity | Early Phase 1 | Recruiting | Mayo Clinic | 24 | 2024-01-01 | 2026-05-22 |
| Continuing Somatostatin Analogues Upon Progression in Neuroendocrine Tumour pAtients Somatostatin analog - Gastroenteropancreatic Neuroendocrine Tumor | Phase 4 | Recruiting | University Hospital, Antwerp | 270 | 2023-06-28 | 2024-06-14 |
| Direct Measurement of Proinsulin Clearance in Humans Somatostatin - Healthy | Phase 4 | Withdrawn | Mayo Clinic | 2022-11-01 | 2022-12-15 | |
| The Effect of Lifestyle-induced Hepatic Steatosis on Glucagon-stimulated Amino Acid Turnover Glucagon - Non-Alcoholic Fatty Liver Disease, Glucagon Resistance | Not applicable | Completed | Malte Palm Suppli, MD | 20 | 2021-02-08 | 2023-05-11 |
| Somatostatin Analogues With Perioperative Antibiotics Versus Prolonged Antibiotics Somatostatin analog - Pancreatic Diseases | Phase 2 / Phase 3 | Suspended | Mayo Clinic | 103 | 2020-11-17 | 2026-04-03 |
| Rediscovering Biomarkers for the Diagnosis and Early Treatment Response in NEN (REBORN) Somatostatin analog; chemotherapy - Neuroendocrine Tumors, Neuroendocrine Neoplasm | Recruiting | University of Roma La Sapienza | 60 | 2020-09-14 | 2025-04-03 | |
| Fatigue and Quality of Life in Patients With Neuroendocrine Neoplasia Somatostatin analog - Neuroendocrine Tumors (NET) Health Related Qualito of Life (HRQoL) | Unknown | University of Aarhus | 100 | 2020-09-01 | 2020-09-21 | |
| Effect of Fasting Free Fatty Acids and Fasting Glucose on 1st and 2nd Phase Insulin Secretion Somatostatin, Dextrose, Insulin - Healthy | Phase 4 | Withdrawn | Mayo Clinic | 2020-02-01 | 2022-09-09 | |
| Somatostatin in Living Donor Liver Transplantation Somatostatin, Placebo - End Stage Liver DIsease, Portal Hypertension | Phase 4 | Unknown | King Faisal Specialist Hospital & Research Center | 56 | 2019-12-01 | 2019-09-27 |
| The Role of Somatostatin in the Hemodynamics of the Hepatic Circulation in Patients Undergoing Liver Resection Somatostatin, Placebo - Portal Hypertension | Phase 3 | Unknown | Laikο General Hospital, Athens | 40 | 2019-08-01 | 2019-07-08 |
| Terlipressin on Effect of Renal Function in Cirrhotic Patients With Acute Gastrointestinal Hemorrhage Terlipressin, Somatostatin, Octreotide - Variceal Hemorrhage, Cirrhosis, Liver | Completed | General Hospital of Shenyang Military Region | 1682 | 2019-03-01 | 2019-07-05 | |
| Liver Glycogen and Hypoglycemia in Humans Low Fructose, Saline, Somatostatin - Hypoglycemia; Iatrogenic | Phase 1 | Active not recruiting | Jason Winnick | 40 | 2018-08-02 | 2025-07-25 |
| Somatostatin Prevent Post-operation Pancreatic Fistula in Intermediate Risk Patients After Pancreaticoduodenectomy Somatostatin - Pancreatic Fistula | Phase 4 | Completed | Peking Union Medical College Hospital | 205 | 2018-06-22 | 2020-02-13 |
| Terlipression Prevent Developing of Acute Kidney Injury During Upper-gastroentestinal Bleeding Terlipressin, Somatostatin - Cirrhosis, Liver, Upper Gastrointestinal Bleeding | Phase 4 | Completed | Changhai Hospital | 54 | 2018-01-01 | 2020-04-22 |
| Octreotide LAR in the Induction of Immunologic Response in NENs Patients Octreotide Acetate - Neuroendocrine Tumors | Phase 2 | Completed | National Cancer Institute, Naples | 34 | 2017-06-28 | 2020-09-10 |
Showing 20 of 49. Sign in to see all of them.
Neuroendocrine Tumors (6) · Liver Cirrhosis (5) · Hypertension, Portal (4) · Acromegaly (3) · Diabetes Mellitus, Type 1 (3) · Hemorrhage (3) · Acute Kidney Injury (2) · Diabetes Mellitus (2) · Esophageal and Gastric Varices (2) · Fibrosis (2) · Hypoglycemia (2) · Insulin Resistance (2) · Non-alcoholic Fatty Liver Disease (2) · Pancreatic Fistula (2) · Varicose Veins (2)
Mayo Clinic (5) · General Hospital of Shenyang Military Region (3) · University of Aarhus (3) · National Cancer Institute, Naples (2) · University of Minnesota (2) · Assistance Publique - Hôpitaux de Paris (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Changhai Hospital (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dana-Farber Cancer Institute (1) · Erzhen Chen (1) · First Affiliated Hospital, Sun Yat-Sen University (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · Govind Ballabh Pant Hospital (1) · Hadassah Medical Organization (1)
China (11) · United States (10) · Denmark (5) · Italy (4) · Germany (3) · Netherlands (3) · France (2) · South Korea (2) · Spain (2) · Austria (1) · Belgium (1) · Czechia (1) · Hungary (1) · India (1) · Poland (1)
Elizabeth R Seaquist, MD (2) · A Colao, M.D. (1) · A Faggiano, M.D. (1) · Adrian Vella (1) · Adrian Vella, MD (1) · Andrea M Isidori, MD, PhD (1) · C Gallo, MD (1) · Christoph Kapitza, MD (1) · Dieter Broering, MD, PhD (1) · Dong-Sik Kim, Professor (1) · En-Qiang Mao, M.D. & Ph.D. (1) · Er-Zhen Chen, M.D. & Ph.D. (1) · F Fiore, MD (1)
PMID 32860184, PMID 10761474, PMID 1350562, PMID 15743361, PMID 15743362, PMID 23278466, PMID 24977398, PMID 26628838, PMID 28911152, PMID 29548882, PMID 30508958, PMID 30726726, PMID 30733330, PMID 34453212, PMID 37967235, PMID 38161497, PMID 38662619, PMID 39834129, PMID 40615151, PMID 42866259
2008 (1), 2016 (1), R01DK040484 (1), R01DK078645 (1), R01DK078646 (1), U24DK100469 (1)