17 completed. 17 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 17 | Completed 17 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow End-Stage Renal Disease: new trials by email Literature Review of End-Stage Renal Disease trials Research Report on End-Stage Renal Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007) MK-2060, Placebo - End-Stage Renal Disease, End-Stage Kidney Disease | Phase 2 | Completed | Merck Sharp & Dohme LLC | 506 | 2021-09-17 | 2026-02-11 |
| Study to Investigate the Safety of a Drug Called Osocimab at Low and High Doses in Adult Patients With Kidney Failure Requiring Regular Hemodialysis BAY1213790 (Osocimab), Placebo - End-stage Renal Disease, Prevention of Thromboembolic Events | Phase 2 | Completed | Bayer | 704 | 2020-08-28 | 2023-07-21 |
| Anti-Cytokine Therapy for Hemodialysis InflammatION Anakinra, Placebo - End-Stage Renal Disease | Phase 2 | Completed | University of Pennsylvania | 80 | 2017-12-15 | 2023-03-14 |
| Evaluating the Effect of Fumaria Parviflora L. in Uremic Pruritus Wheat, Fumaria - End-Stage Renal Disease, Pruritus | Phase 2 | Completed | Shiraz University of Medical Sciences | 63 | 2015-07-01 | 2016-02-02 |
| Safety and Cardiovascular Efficacy of Spironolactone in Dialysis-Dependent ESRD Trial Spironolactone - End-Stage Renal Disease | Phase 2 | Completed | University of Pennsylvania | 129 | 2014-11-01 | 2019-07-23 |
| Two phosphAte taRGets in End-stage Renal Disease Trial (TARGET) Calcium carbonate ( Intensive phosphate control), Calcium carbonate (Liberalized phosphate control) - End-stage Renal Disease | Phase 2 | Completed | Unity Health Toronto | 104 | 2014-01-01 | 2015-06-23 |
| Eculizumab for Prevention and Treatment of Kidney Graft Reperfusion Injury eculizumab - End-Stage Renal Disease, Kidney Failure | Phase 2 | Completed | Russian Academy of Medical Sciences | 57 | 2012-09-01 | 2018-08-31 |
| Vitamin D3 Supplementation in Dialysis Patients Cholecalciferol, Placebo - End-Stage Renal Disease | Phase 2 | Completed | Regional Hospital Holstebro | 64 | 2011-02-01 | 2013-05-29 |
| Safety Trial of Single Versus Multiple Dose Thymoglobulin Induction in Kidney Transplantation Single-dose rabbit Anti-thymocyte Globulin induction, Divided-dose rabbit Anti-thymocyte Globulin induction - End-Stage Renal Disease, Kidney Failure | Phase 2 | Completed | Wright State University | 99 | 2010-03-01 | 2015-12-07 |
| L-Carnitine as an Osmo-metabolic Agent for Peritoneal Dialysis L-Carnitine - End-Stage Renal Disease | Phase 2 | Completed | Iperboreal Pharma Srl | 5 | 2009-06-01 | 2019-06-25 |
| A Safety and Tolerability Study of Zerenex (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD) ferric citrate - Hyperphosphatemia, End-stage Renal Disease | Phase 2 | Completed | Keryx Biopharmaceuticals | 55 | 2008-03-01 | 2017-04-04 |
| Quality of Life Therapy for Adults With ESRD Awaiting Renal Transplantation Quality of Life Therapy, Supportive Therapy - End-stage Renal Disease | Phase 2 / Phase 3 | Completed | Beth Israel Deaconess Medical Center | 65 | 2007-01-01 | 2012-01-06 |
| Provision of Antioxidant Therapy in Hemodialysis (PATH) Study Alpha, gamma, beta, and delta (mixed) tocopherols, Alpha lipoic acid, Placebo - End-stage Renal Disease | Phase 2 | Completed | Vanderbilt University | 385 | 2006-04-01 | 2012-01-11 |
| Simultaneous Islet-Kidney Transplantation in Patients of Type 1 Diabetes With End-stage Renal Disease simultaneous islet-kidney transplantation - Type 1 Diabetes Mellitus, End-stage Renal Disease | Phase 1 / Phase 2 | Completed | Fuzhou General Hospital | 7 | 2005-06-01 | 2011-09-16 |
| Improving Patient-clinician Communication About End-of-life Care Patient-Centered Advance Care Planning - End-stage Renal Disease | Phase 2 | Completed | University of Pittsburgh | 42 | 2005-01-01 | 2017-05-31 |
| L-Carnitine in Peritoneal Dialysis L-carnitine - End-Stage Renal Disease | Phase 2 | Completed | Iperboreal Pharma Srl | 4 | 2004-06-01 | 2010-02-23 |
| Growth Hormone Treatment in Adult Patients With Chronic Kidney Disease somatropin - Chronic Kidney Disease, End-Stage Renal Disease | Phase 2 | Completed | Novo Nordisk A/S | 140 | 2003-04-01 | 2017-01-24 |
Kidney Failure, Chronic (17) · Renal Insufficiency (3) · Diabetes Mellitus, Type 1 (1) · Hyperphosphatemia (1) · Infections (1) · Pruritus (1) · Rejection, Psychology (1) · Renal Insufficiency, Chronic (1) · Vitamin D Deficiency (1)
Chronic Disease (17) · Disease Attributes (17) · Female Urogenital Diseases (17) · Female Urogenital Diseases and Pregnancy Complications (17) · Kidney Diseases (17) · Male Urogenital Diseases (17) · Pathologic Processes (17) · Pathological Conditions, Signs and Symptoms (17) · Urogenital Diseases (17) · Urologic Diseases (17) · Renal Insufficiency, Chronic (16) · Renal Insufficiency (14) · Nutritional and Metabolic Diseases (3) · Metabolic Diseases (2) · Autoimmune Diseases (1)
Carnitine (2) · Calcium Carbonate (1) · Cholecalciferol (1) · Flour (1) · Fumariae herba (1) · Gamma Rays (1) · Human Growth Hormone (1) · Interleukin 1 Receptor Antagonist Protein (1) · Palliative Care (1) · Spironolactone (1) · Thioctic Acid (1) · Tocopherols (1) · Vitamin E (1) · YY1 Transcription Factor (1) · eculizumab (1)
Iperboreal Pharma Srl (2) · University of Pennsylvania (2) · Bayer (1) · Beth Israel Deaconess Medical Center (1) · Fuzhou General Hospital (1) · Keryx Biopharmaceuticals (1) · Merck Sharp & Dohme LLC (1) · Novo Nordisk A/S (1) · Regional Hospital Holstebro (1) · Russian Academy of Medical Sciences (1) · Shiraz University of Medical Sciences (1) · Unity Health Toronto (1) · University of Pittsburgh (1) · Vanderbilt University (1) · Wright State University (1)
United States (8) · Italy (4) · Russia (3) · Australia (2) · Bulgaria (2) · Canada (2) · Czechia (2) · Denmark (2) · Germany (2) · Greece (2) · Israel (2) · Poland (2) · Portugal (2) · Sweden (2) · Argentina (1)
Alp Ikizler, MD (1) · Arduino Arduini, M.D. (1) · Arduino Arduini, MD (1) · Erling B Pedersen, M.D., M.Sci. (1) · James R. Rodrigue, PhD (1) · Jamshid Roozbeh, MD (1) · Jianming Tan, professor (1) · Jonathan Himmelfarb, MD (1) · Julia B Lewis, MD (1) · Laura Dember, MD (1) · Laura M Dember, MD (1) · Mario Bonomini, M.D. (1) · Mario Bonomini, MD (1)
PMID 17554147, PMID 18633105, PMID 21525850, PMID 24661355, PMID 26696251, PMID 33283264, PMID 33586138, PMID 38365952
2019 (1), R21DK077322 (1), U01DK099919 (1)