172 completed, 37 unknown, 16 terminated, 12 recruiting. 114 Not applicable, 37 Phase 4, 29 Phase 2, 20 Phase 1, 20 Phase 3.
Follow End-Stage Renal Disease: new trials by email Literature Review of End-Stage Renal Disease trials Research Report on End-Stage Renal Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Technology-enabled Social Network Intervention to Increase Live Donor Kidney Transplantation Digital education outreach intervention for kidney transplant access and human guide, Digital education outreach intervention for kidney transplant access only (unguided) - End-Stage Renal Disease, Chronic Kidney Diseases | Not applicable | Not yet recruiting | State University of New York at Buffalo | 550 | 2027-10-01 | 2026-10-20 |
| Ramipril vs. Amlodipine in Pediatric Hemodialysis Patients Ramipril tablet, Amlodipine tablet - Endothelial Dysfunction, End-Stage Renal Disease | Phase 3 | Not yet recruiting | Ain Shams University | 50 | 2026-11-01 | 2026-10-21 |
| Study on the Safety and Efficacy of a Time-of-Day-Based Individualized Tacrolimus Dosing Regimen in Kidney Transplant Recipients Chronotherapy-based individualized low-morning high-evening tacrolimus dosing, conventional dosing regimen - End-Stage Renal Disease | Phase 4 | Not yet recruiting | The First Affiliated Hospital of Guangzhou Medical University | 100 | 2026-10-25 | 2026-10-16 |
| Effects of Horticultural Therapy on Acute Stress and Salivary Cortisol Levels in Hemodialysis Patients Horticultural Therapy - End-Stage Renal Disease, Renal Dialysis | Not applicable | Not yet recruiting | Ataturk University | 80 | 2026-10-15 | 2026-10-28 |
| The Effect of Intradialytic Exercise on Postural Abnormalities Supervised Intradialytic Multimodal Exercise Program - End-Stage Renal Disease, Hemodialysis Complication | Not applicable | Recruiting | Pardis Specialized Wellness Institute | 98 | 2026-08-25 | 2026-09-01 |
| The Microcirculation, Dialysis Modality and Sequestered Salt Hemodialysis (DNa = PNa), Hemodialysis (DNa<PNa), Hemodialysis after isolated ultrafiltration (DNa=PNa) - End-stage Renal Disease | Not applicable | Recruiting | Amsterdam UMC, location VUmc | 23 | 2026-06-02 | 2026-09-11 |
| A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006) MK-2828 - Chronic Kidney Failure, End-Stage Renal Disease | Phase 1 | Completed | Merck Sharp & Dohme LLC | 18 | 2026-03-02 | 2026-09-15 |
| Autogenic Relaxation and Murottal Therapy in Hemodialysis Patients Autogenic Relaxation and Surah Ar-Rahman Murottal Therapy, listening to dangdut music - Chronic Kidney Disease Stage V, End-Stage Renal Disease | Not applicable | Not yet recruiting | Universitas Muhammadiyah Surakarta | 76 | 2026-03-01 | 2026-02-17 |
| Levocarnitine for Reducing ESA Requirements in Hemodialysis Patients With Renal Anemia Levocarnitine Injection, Usual ESA-Based Anemia Care - Anemia, Kidney Failure | Phase 4 | Not yet recruiting | Shaikh Zayed Hospital, Lahore | 94 | 2025-09-15 | 2025-09-12 |
| The Effect of Magnetic Stimulation on Low Back Pain Relief and Muscle Mass Maintenance in Patients With ESRD Effects of applying magnetic stimulation - End-Stage Renal Disease | Not applicable | Recruiting | Bundang CHA Hospital | 18 | 2025-08-06 | 2025-09-19 |
| Effect of Intra-Dialytic Muscle Energy Technique on Restless Leg Syndrome in Hemodialysis Patients Muscle Energy Technique, Routine Medical Treatment and Hemodialysis - Restless Legs Syndrome (RLS), End-Stage Renal Disease | Not applicable | Completed | Cairo University | 60 | 2025-08-01 | 2026-08-05 |
| Cuffless BP Monitoring in Hemodialysis CART BP Pro - End-Stage Renal Disease | Enrolling by invitation | Gangnam Severance Hospital | 240 | 2025-07-01 | 2026-08-24 | |
| Views on Information Resources for Kidney Transplantation Patients Views on Information Resources for Kidney Transplantation Patients - End-Stage Renal Disease | Not applicable | Not yet recruiting | University of Auckland, New Zealand | 60 | 2025-06-01 | 2025-06-15 |
| CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk Ex Vivo CRISPR-Cas9 Gene Editing of Donor Kidney, Kidney Transplantation with Standard Care - End-Stage Renal Disease, End Stage Renal Disease on Dialysis | Phase 1 / Phase 2 | Recruiting | AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC | 90 | 2025-06-01 | 2025-07-08 |
| The Efficacy and Safety of Guilu Erxian Jiao in the Treatment of Intradialytic Hypotension Guilu Erxian Jiao - Intradialytic Hypotension, End-Stage Renal Disease | Phase 2 | Not yet recruiting | Chang Gung Memorial Hospital | 34 | 2025-06-01 | 2025-05-20 |
| The Role of Toll-like Receptor-4 in Periodontitis Patients With End-stage Renal Disease in a Sample of Egyptian Population Periodontitis, End-stage Renal Disease | Recruiting | Ain Shams University | 100 | 2025-04-01 | 2025-07-04 | |
| The Effect of Home-based Exercise on Postural Abnormalities Home-based Tele Exercise - End-Stage Renal Disease, Hemodialysis Complication | Not applicable | Completed | Pardis Specialized Wellness Institute | 30 | 2025-03-15 | 2025-08-12 |
| Continuous Glucose Monitoring in People With Diabetes on Dialysis Diabetes Mellitus, End-Stage Renal Disease | Active not recruiting | University of Nottingham | 40 | 2024-12-31 | 2026-04-29 | |
| Artificial Intelligence-based Techniques to Characterize KIdney Microstructure on Histological ImagEs End-Stage Renal Disease | Active not recruiting | Mario Negri Institute for Pharmacological Research | 100 | 2024-11-08 | 2024-11-15 | |
| Effects of Mindfulness Meditation on Hemodialysis Patients Mindfulness Meditation - End-Stage Renal Disease, Hemodialysis Complication | Not applicable | Completed | University of Jordan | 56 | 2024-09-15 | 2025-04-20 |
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Kidney Failure, Chronic (263) · Renal Insufficiency, Chronic (31) · Renal Insufficiency (19) · Cardiovascular Diseases (11) · Hyperphosphatemia (11) · Kidney Diseases (11) · Inflammation (8) · Diabetes Mellitus (7) · Hypertrophy, Left Ventricular (5) · Anemia (4) · Arteriovenous Fistula (4) · Motor Activity (4) · Diabetes Mellitus, Type 1 (3) · Diabetes Mellitus, Type 2 (3) · Heart Failure (3)
Chronic Disease (263) · Disease Attributes (263) · Female Urogenital Diseases (263) · Female Urogenital Diseases and Pregnancy Complications (263) · Male Urogenital Diseases (263) · Pathologic Processes (263) · Pathological Conditions, Signs and Symptoms (263) · Urogenital Diseases (263) · Urologic Diseases (261) · Kidney Diseases (252) · Renal Insufficiency (244) · Renal Insufficiency, Chronic (232) · Nutritional and Metabolic Diseases (34) · Metabolic Diseases (28) · Cardiovascular Diseases (26)
Tacrolimus (7) · Renal Dialysis (6) · Mycophenolic Acid (5) · Sirolimus (5) · Cholecalciferol (4) · Cyclosporine (4) · Prednisone (4) · ferric citrate (4) · Carnitine (3) · Human Growth Hormone (3) · Methylprednisolone (3) · Ribavirin (3) · thymoglobulin (3) · Acetylcysteine (2) · Antilymphocyte Serum (2)
National Taiwan University Hospital (6) · Emory University (5) · National Institute of Allergy and Infectious Diseases (NIAID) (5) · University of Pennsylvania (5) · Beth Israel Deaconess Medical Center (4) · Chulalongkorn University (4) · Ege University (4) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (4) · Merck Sharp & Dohme LLC (4) · University of Pittsburgh (4) · Ain Shams University (3) · Amsterdam UMC, location VUmc (3) · China Medical University Hospital (3) · Iperboreal Pharma Srl (3) · Keryx Biopharmaceuticals (3)
United States (97) · Canada (18) · Taiwan (16) · China (15) · Germany (14) · France (12) · Italy (10) · South Korea (10) · Egypt (8) · Turkey (Türkiye) (8) · Denmark (7) · Spain (7) · United Kingdom (7) · Brazil (6) · Israel (6)
Ercan Ok, MD (3) · Khajohn Tiranathanagul, MD (3) · Muriel PC Grooteman, MD PhD (3) · Alfonso M. M Cueto-Manzano, MD, MSc, PhD (2) · Andrew T Yan, MD (2) · Ann Eldred, MD (2) · Didier Mandelbrot, MD (2) · Ercan Ok, M.D (2) · James R Rodrigue, Ph.D. (2) · Julia B Lewis, MD (2) · Kirsten L Johansen, MD (2) · Laura Dember, MD (2) · Lisa C. Hudgins, MD (2)
PMID 37651553, PMID 35018639, PMID 36472416, PMID 27203778, PMID 33586138, PMID 35224730, PMID 40576086, PMID 12189242, PMID 15049798, PMID 15213282, PMID 16382014, PMID 16687625, PMID 17554147, PMID 17634080, PMID 18216355, PMID 18416737, PMID 18497677, PMID 18633105, PMID 18643743, PMID 18941347, PMID 18945992, PMID 19515802, PMID 19663893, PMID 19714613, PMID 19846545, PMID 19962805, PMID 19965537, PMID 20007751, PMID 20185606, PMID 20947533, PMID 21030579, PMID 21051503, PMID 21176752, PMID 21194971, PMID 21252253, PMID 21401720, PMID 21525850, PMID 21538345, PMID 21590439, PMID 21793744, PMID 22172590, PMID 22237061, PMID 22510472, PMID 22889943, PMID 23357165, PMID 23369827, PMID 23383316, PMID 23624993, PMID 24030917, PMID 24101420
2014 (2), 2019 (2), U01DK099919 (2), 2005 (1), 2015 (1), 2018 (1), K23AT006965 (1), K23DK123384 (1), K25DK072085 (1), P01DK013083 (1), R01AG065365 (1), R01DK079665 (1), R01DK098727 (1), R01DK098744 (1), R01DK114085 (1)