9 completed, 2 recruiting, 2 unknown, 2 withdrawn. 16 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 16 | Completed 9, Recruiting 2, Unknown 2, Withdrawn 2, Not yet recruiting 1 |
Follow Dystocia: new trials by email Literature Review of Dystocia trials Research Report on Dystocia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial Carbetocin, Oxytocin, Placebo Saline Infusion - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Recruiting | Mansoura University | 332 | 2026-08-08 | 2026-10-09 |
| Oxytocin Bolus Versus Infusion in High-Risk Patients Undergoing Elective Cesarean Section (INBOX-HR) Oxytocin Bolus or Oxytocin Infusion - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Not yet recruiting | Stony Brook University | 180 | 2026-08-01 | 2026-08-03 |
| Calcium Carbonate to Augment Labor Contractions Calcium Carbonate 500 MG, Standard Dose Synthetic Pitocin - Labor Dystocia, Labor Induction | Phase 4 | Recruiting | Weill Medical College of Cornell University | 60 | 2024-11-18 | 2025-10-23 |
| Comparison Between Propess and Cook Double-balloon Catheter for Cervical Priming Cook double-balloon catheter - Delivery Problem | Phase 4 | Unknown | The University of Hong Kong | 28 | 2024-06-01 | 2024-07-24 |
| Multimodal Uterotonics at the Time of Cesarean Section in Laboring Patients Methylergonovine, Normal Saline (placebo) - Uterine Atony With Hemorrhage | Phase 4 | Completed | Cynthia Wong | 160 | 2019-06-08 | 2022-08-01 |
| Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial 15-methyl prostaglandin F2α, Methylergonovine Maleate - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Completed | Brigham and Women's Hospital | 100 | 2019-03-01 | 2025-10-16 |
| Role of Tranexamic Acid Versus Uterine Cooling at Caesarean Section Tranexamic Acid, Intraoperative Uterine Cooling - Hemorrhage of Cesarean Section and/or Perineal Wound, Postpartum Hemorrhage | Phase 4 | Completed | Talkha Central Hospital | 100 | 2016-06-01 | 2016-09-05 |
| An Evidence Based Protocol for Oxytocin Administration in Vaginal Delivery Oxytocin - Uterine Atony, Postpartum Hemorrhage | Phase 4 | Withdrawn | NYU Langone Health | 2015-11-01 | 2017-07-31 | |
| Comparison of Low-dose and High-dose Oxytocin Regimens for Labor Augmentation Oxytocin, Sodium Chloride 0.9% - Dystocia | Phase 4 | Completed | Northwestern University | 1003 | 2015-09-28 | 2022-02-11 |
| Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section Carbetocin - Uterine Atony, Post-partum Hemorrhage | Phase 4 | Completed | Laval University | 72 | 2012-04-01 | 2013-05-29 |
| ED90 Determination of Carbetocin for the Prevention of Uterine Atony in Women Undergoing an Elective Cesarean Delivery Carbetocin - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Unknown | Maisonneuve-Rosemont Hospital | 40 | 2012-03-01 | 2013-02-15 |
| Does Intramyometrial Oxytocin Improve Outcome in Elective Cesarean Delivery? Oxytocin, Saline - Postpartum Hemorrhage, Uterine Atony | Phase 4 | Withdrawn | University of Saskatchewan | 2011-08-01 | 2012-01-11 | |
| Oxytocin And Uterotonic Agent Use For Cesarean Delivery Oxytocin Infusion, Oxytocin Bolus - Uterine Atony, Hypotension | Phase 4 | Completed | Brigham and Women's Hospital | 60 | 2011-04-01 | 2017-06-29 |
| Oxytocin Regimen to Prevent Atony and Postpartum Hemorrhage During Vaginal Delivery: 3-arm RCT Oxytocin - Uterine Atony, Postpartum Hemorrhage | Phase 4 | Completed | University of Alabama at Birmingham | 1798 | 2008-11-01 | 2016-04-08 |
| Up-Down Oxytocin Infusion Oxytocin infusion - Uterine Atony | Phase 4 | Completed | IWK Health Centre | 40 | 2008-06-01 | 2011-11-02 |
| Buccal Misoprostol During Cesarean Section for Preventing Postpartum Hemorrhage Misoprostol, Folic Acid - Postpartum Hemorrhage | Phase 4 | Completed | Hospital Universitario Dr. Jose E. Gonzalez | 123 | 2008-02-01 | 2018-10-11 |
Uterine Inertia (13) · Postpartum Hemorrhage (10) · Blood Loss, Surgical (1) · Hemorrhage (1) · Hypotension (1)
Female Urogenital Diseases and Pregnancy Complications (16) · Obstetric Labor Complications (16) · Pregnancy Complications (16) · Urogenital Diseases (16) · Pathologic Processes (11) · Pathological Conditions, Signs and Symptoms (11) · Hemorrhage (10) · Puerperal Disorders (10) · Uterine Hemorrhage (10) · Cardiovascular Diseases (1) · Intraoperative Complications (1) · Vascular Diseases (1)
Oxytocin (5) · Methylergonovine (3) · Sodium Chloride (3) · carbetocin (3) · Misoprostol (2) · Saline Solution (2) · Calcium Carbonate (1) · Carboprost (1) · Folic Acid (1) · Tranexamic Acid (1) · carboprost tromethamine (1)
Brigham and Women's Hospital (2) · Cynthia Wong (1) · Hospital Universitario Dr. Jose E. Gonzalez (1) · IWK Health Centre (1) · Laval University (1) · Maisonneuve-Rosemont Hospital (1) · Mansoura University (1) · NYU Langone Health (1) · Northwestern University (1) · Stony Brook University (1) · Talkha Central Hospital (1) · The University of Hong Kong (1) · University of Alabama at Birmingham (1) · University of Saskatchewan (1) · Weill Medical College of Cornell University (1)
United States (6) · Canada (4) · Egypt (1) · Hong Kong (1) · Mexico (1) · Saudi Arabia (1)
Alan Peaceman, MD (1) · Alan T Tita, MD, PhD (1) · Amro M Hetta, M.B., Ch.B. (1) · Christian Loubert, MD, FRCPC (1) · David C Campbell, MD, FRCPC (1) · Jade King, BS (1) · Kevin Fitzpatrick, MD (1) · Lawrence C Tsen, MD (1) · Moeun Son, MD (1) · Moeun Son, MD, MSCI (1) · Mohamed A Tolba, MD (1) · Monica K San Vicente, MD (1) · Naida M Cole, MD (1) · Nicole M Masse, MD (1)
PMID 20238255, PMID 22227638, PMID 26534874, PMID 33232518, PMID 33957657, PMID 35852267, PMID 36649339, PMID 39326051
K12HD001258 (1)